Giuseppe Giannini | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
IFN-α neutralizing antibodies distinguish LADA from early-onset type 1 diabetes	THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM	2025
Circulating Cancer-Associated Macrophage-like Cells as a Blood-Based Biomarker of Response to Immune Checkpoint Inhibitors	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2024
Prenatal Alcohol Exposure and Metabolic Disorders in Pediatrics: The Role of the Oxidative Stress—A Review of the Literature	CHILDREN	2024
MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation	ONCOGENE	2024
SMURF1 and SMURF2 directly target GLI1 for ubiquitination and proteasome-dependent degradation	CELL DEATH DISCOVERY	2024
Molecular profiling of male breast cancer by multigene panel testing: Implications for precision oncology	FRONTIERS IN ONCOLOGY	2023
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation	CANCER LETTERS	2023
Genomic landscape and survival analysis of ctDNA “neo-RAS wild-type” patients with originally RAS mutant metastatic colorectal cancer	FRONTIERS IN ONCOLOGY	2023
Male breast cancer risk associated with pathogenic variants in genes other than BRCA1/2: an Italian case-control study	EUROPEAN JOURNAL OF CANCER	2023
The Multiple Faces of the MRN Complex: Roles in Medulloblastoma and Beyond	CANCERS	2023
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma	CELL DEATH AND DIFFERENTIATION	2023
Impact of SARS-CoV-2 vaccination on FcγRIIIA/CD16 dynamics in Natural Killer cells: relevance for antibody-dependent functions	FRONTIERS IN IMMUNOLOGY	2023
FACILITATE: A real-world, multicenter, prospective study investigating the utility of a rapid, fully automated real-time PCR assay versus local reference methods for detecting epidermal growth factor receptor variants in NSCLC	PATHOLOGY ONCOLOGY RESEARCH	2023
A single-cell transcriptomic analysis of Neuroblastomas revealed a selective cGAS-STING pathway suppression in malignant cells	PROCEEDINGS IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE	2023
RAS mutation conversion in bevacizumab-treated metastatic colorectal cancer patients: a liquid biopsy based study	CANCERS	2022
An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy	BIOLOGY DIRECT	2022
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma	NEUROPATHOLOGY & APPLIED NEUROBIOLOGY	2022
5FU/Oxaliplatin-induced Jagged1 cleavage counteracts apoptosis induction in colorectal cancer: a novel mechanism of intrinsic drug resistance	FRONTIERS IN ONCOLOGY	2022
True conversions from RAS mutant to RAS wild-type in circulating tumor DNA from metastatic colorectal cancer patients as assessed by methylation and mutational signature	CANCER LETTERS	2021
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors	ONCOGENE	2021

Progetti di Ricerca

Dissecting the role of the Nijmegen breakage syndrome protein in SHH-dependent tumorigenesis
Repressing or enhancing replication stress: the two sides of the coin to understand and tackle MYCN-dependent tumors.

Laboratori di ricerca

LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 224 225

LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 208