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giuseppe.giannini@uniroma1.it
Giuseppe Giannini
Professore Ordinario
Struttura:
DIPARTIMENTO DI MEDICINA MOLECOLARE
E-mail:
giuseppe.giannini@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Molecular profiling of male breast cancer by multigene panel testing: Implications for precision oncology
FRONTIERS IN ONCOLOGY
2023
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation
CANCER LETTERS
2023
RAS mutation conversion in bevacizumab-treated metastatic colorectal cancer patients: a liquid biopsy based study
CANCERS
2022
An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy
BIOLOGY DIRECT
2022
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma
NEUROPATHOLOGY & APPLIED NEUROBIOLOGY
2022
5FU/Oxaliplatin-induced Jagged1 cleavage counteracts apoptosis induction in colorectal cancer: a novel mechanism of intrinsic drug resistance
FRONTIERS IN ONCOLOGY
2022
True conversions from RAS mutant to RAS wild-type in circulating tumor DNA from metastatic colorectal cancer patients as assessed by methylation and mutational signature
CANCER LETTERS
2021
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors
ONCOGENE
2021
A multidisciplinary approach for the differential diagnosis between multiple primary lung adenocarcinomas and intrapulmonary metastases
PATHOLOGY RESEARCH AND PRACTICE
2021
Comparison of two blood-based genotyping tests to investigate the KRAS G12C mutation in patients with non-small-cell lung cancer at failure of first-line treatments
DIAGNOSTICS
2021
Transcriptome of male breast cancer matched with germline profiling reveals novel molecular subtypes with possible clinical relevance
CANCERS
2021
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module
CELL REPORTS
2020
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer
FRONTIERS IN ONCOLOGY
2020
PIK3CA somatic mutation in sinonasal teratocarcinosarcoma.
AURIS, NASUS, LARYNX
2020
Matched germline and tumor profiling in male breast cancer for the discovery of molecular subtypes with clinical relevance
Cancer ResearchCANCER RESEARCH
2020
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation
CELL DEATH & DISEASE
2020
A novel BRCA2 splice variant identified in a young woman
MOLECULAR GENETICS & GENOMIC MEDICINE
2020
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer
CANCERS
2019
Transient disappearance of RAS mutant clones in plasma: A counterintuitive clinical use of EGFR inhibitors in RAS mutant metastatic colorectal cancer
CANCERS
2019
Next-generation sequencing of BRCA1 and BRCA2 genes for rapid detection of germline mutations in hereditary breast/ovarian cancer
PEERJ
2019
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Progetti di Ricerca
Dissecting the role of the Nijmegen breakage syndrome protein in SHH-dependent tumorigenesis
Repressing or enhancing replication stress: the two sides of the coin to understand and tackle MYCN-dependent tumors.
Laboratori di ricerca
LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 224 225
LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 208
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