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loretta.tuosto@uniroma1.it
Loretta Tuosto
Professore Associato
Struttura:
DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "CHARLES DARWIN"
E-mail:
loretta.tuosto@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
A non-conserved amino acid variant regulates differential signalling between human and mouse CD28
NATURE COMMUNICATIONS
2018
CD28 between tolerance and autoimmunity: The side effects of animal models [version 1; referees: 2 approved]
F1000RESEARCH
2018
Editorial: Membrane lipids in T cell functions
FRONTIERS IN IMMUNOLOGY
2018
ISA-2011B, a phosphatidylinositol 4-phosphate 5-kinase a inhibitor, impairs CD28-dependent costimulatory and pro-inflammatory signals in human T lymphocytes
FRONTIERS IN IMMUNOLOGY
2017
CD28 costimulatory signals in T lymphocyte activation: Emerging functions beyond a qualitative and quantitative support to TCR signalling
CYTOKINE & GROWTH FACTOR REVIEWS
2016
Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation
FRONTIERS IN IMMUNOLOGY
2016
Phosphatidylinositol 4-phosphate 5-kinase β controls recruitment of lipid rafts into the immunological synapse
JOURNAL OF IMMUNOLOGY
2016
Phosphatidylinositol 4-phosphate 5-kinase α and Vav1 mutual cooperation in CD28-mediated actin remodeling and signaling functions
JOURNAL OF IMMUNOLOGY
2015
Targeting Inflammatory T Cells in Multiple Sclerosis: Current Therapies and Future Challenges
AUSTIN JOURNAL OF MULTIPLE SCLEROSIS & NEUROIMMUNOLOGY
2015
The multifaceted role of PIP2 in leukocyte biology
CELLULAR AND MOLECULAR LIFE SCIENCES
2015
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Progetti di Ricerca
Bacterial superantigens in inflammatory autoimmune diseases: therapeutic targeting of CD28 costimulatory pathway to modulate excessive T cell inflammatory responses
Characterization of the signalling motifs of human CD28 involved in the lethal inflammatory responses to bacterial superantigen toxins
Role of CD28 and associated class 1A PI3K in the regulation of the cellular metabolic programs associated to pro-inflammatory T cell responses
Role of IL-6 and NF-kB signalling mediators in CD28-induced IL-17A gene expression and Th17 cell subset expansion
Role of CD28 and associated class 1A PI3K in the regulation of IL-22 production and IL-22-producing T cell amplification
Gruppi di ricerca - Responsabile
Immunologia Cellulare e Mlecolare
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