Stefano Pascarella | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Evidence for mutations in SARS-CoV-2 Italian isolates potentially affecting virus transmission	JOURNAL OF MEDICAL VIROLOGY	2020
Structural analysis of merkel cell polyomavirus (MCPyV) viral capsid protein 1 (VP1) in HIV-1 infected individuals	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2020
Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy	JOURNAL OF INFECTION	2020
Computational classification of MocR transcriptional regulators into subgroups as a support for experimental and functional characterization	BIOINFORMATION	2019
Phylogeny of culex theileri virus flavivirus in Spain, Myanmar, Portugal and Turkey	ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE	2019
Atomistic simulations of GabR transcription factor at microsecond scale	Biophysics@Rome2019 Poster program	2019
In silico identification of structural signatures in Arabidopsis thaliana pectin methylesterases	SIBV - Abstract Book	2019
Conformational transitions induced by γ-amino butyrate binding in GabR, a bacterial transcriptional regulator	SCIENTIFIC REPORTS	2019
A comprehensive computational analysis of Mycobacterium genomes pinpoints the genes co-occurring with ycze, a membrane protein coding gene under the putative control of a mocr, and predicts its function	INTERDISCIPLINARY SCIENCES: COMPUTATIONAL LIFE SCIENCES	2018
Mayaro virus infection, the next epidemic wave after Zika? Evolutionary and structural analysis	ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE	2018
Multi-drug resistant Pseudomonas aeruginosa nosocomial strains: Molecular epidemiology and evolution	MICROBIAL PATHOGENESIS	2018
The MocR-like transcription factors: pyridoxal 5'-phosphate-dependent regulators of bacterial metabolism	THE FEBS JOURNAL	2018
Study of DNA binding and bending by Bacillus subtilis GabR, a PLP-dependent transcription factor	BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS	2017
Salmonella typhimurium PtsJ is a novel MocR-like transcriptional repressor involved in regulating the vitamin B6 salvage pathway	THE FEBS JOURNAL	2017
Hepatitis C virus genotype 3A in a population of injecting drug users in Montenegro: Bayesian and evolutionary analysis	ARCHIVES OF VIROLOGY	2017
Molecular dynamics simulation unveils the conformational flexibility of the interdomain linker in the bacterial transcriptional regulator GabR from Bacillus subtilis bound to pyridoxal 5'-phosphate	PLOS ONE	2017
Zika Virus spreading in South America: evolutionary analysis of emerging neutralizing resistant Phe279Ser strains	ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE	2016
A bioinformatics analysis reveals a group of MocR bacterial transcriptional regulators linked to a family of genes coding for membrane proteins	BIOCHEMISTRY RESEARCH INTERNATIONAL	2016
Structural properties of the linkers connecting the n- and c- terminal domains in the mocr bacterial transcriptional regulators	BIOCHIMIE OPEN	2016
Data from computational analysis of the peptide linkers in the mocr bacterial transcriptional regulators	DATA IN BRIEF	2016

ERC

LS1_8
LS2_11

KET

Big data & computing
Life-science technologies & biotechnologies

Progetti di Ricerca

Sviluppo di un protocollo per l'analisi della distribuzione delle mutazioni più frequenti del virus SARS-CoV-2 e sulla modalità di interazione tra la proteina Spike e anticorpi monoclonali neutralizzanti.
Analisi della mutabilità del proteoma di SarS-CoV-2
Molecular mechanism and evolution of MocRs, a novel family of bacterial transcriptional regulators
Docking-based inverse virtual screening: application to the identification of molecular targets of natural compounds in the recurrent medulloblastoma.

Gruppi di ricerca - Responsabile

Structural bioinformatics and molecular modelling