Carmine Mancone


Titolo Pubblicato in Anno
Letter to the editor: Serum thrombospondin-2 as biomarker in liver diseases, a look beyond NASH HEPATOLOGY 2022
Thrombospondin 1 and 2 along with PEDF inhibit angiogenesis and promote lymphangiogenesis in intrahepatic cholangiocarcinoma JOURNAL OF HEPATOLOGY 2021
Persistent biliary hypoxia and lack of regeneration are key mechanisms in the pathogenesis of post-transplant non-anastomotic strictures HEPATOLOGY 2021
Exogenous and endogenous Phosphoethanolamine transferases differently affect Colistin resistance and fitness in Pseudomonas aeruginosa FRONTIERS IN MICROBIOLOGY 2021
The RNA editing enzyme ADAR2 restricts L1 mobility RNA BIOLOGY 2021
Combination of chemotherapy and PD-1 blockade induces T cell responses to tumor non-mutated neoantigens COMMUNICATIONS BIOLOGY 2020
Homocysteinylated alpha 1 antitrypsin as an antigenic target of autoantibodies in seronegative rheumatoid arthritis patients JOURNAL OF AUTOIMMUNITY 2020
A novel colistin adjuvant identified by virtual screening for ArnT inhibitors JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 2020
Effect of lipid A aminoarabinosylation on Pseudomonas aeruginosa colistin resistance and fitness INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 2020
Titanium-based tetrakis-2,3-[5,6-di(substituted)pyrazino]porphyrazine. Synthesis and characterization EUROPEAN JOURNAL OF INORGANIC CHEMISTRY 2020
Matrisome analysis of intrahepatic cholangiocarcinoma unveils a peculiar cancer-associated extracellular matrix structure CLINICAL PROTEOMICS 2019
Genetic basis and physiological effects of lipid a hydroxylation in pseudomonas aeruginosa PAO1 PATHOGENS 2019
Overexpression of the vitronectin v10 subunit in patients with nonalcoholic steatohepatitis: Implications for noninvasive diagnosis of NASH INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018
Pseudomonas aeruginosa LptE is crucial for LptD assembly, cell envelope integrity, antibiotic resistance and virulence VIRULENCE 2018
Non-enzymatic oligomerization of 3',5' cyclic CMP induced by proton- and UV-irradiation hints at a non-fastidious origin of RNA CHEMBIOCHEM 2017
The laminA/NF-Y protein complex reveals an unknown transcriptional mechanism on cell proliferation ONCOTARGET 2017
ADAR1 restricts LINE-1 retrotransposition NUCLEIC ACIDS RESEARCH 2017
Data on the effects of low iron diet on serum lipid profile in HCV transgenic mouse model DATA IN BRIEF 2017
Iron overload down-regulates the expression of the HIV-1 Rev cofactor eIF5A in infected T lymphocytes PROTEOME SCIENCE 2017
Extracellular matrix molecular remodeling in human liver fibrosis evolution PLOS ONE 2016


  • LS3_4
  • LS4_12


  • Life-science technologies & biotechnologies

Interessi di ricerca

Prof. Carmine Mancone is the manager of the Tumor Microenvironment Laboratory at Sapienza University of Rome. The laboratory works on understanding the molecular basis of the interaction between cancer cells and the tumor microenvironment in liver and biliary tract carcinomas. In particular, the studies focus on the identification of proteins responsible for the remodeling of the extracellular matrix, for the regulation of vascular and lymphatic angiogenesis and for the desmoplastic reaction to understand how the microenvironment influences growth, invasiveness, and metastasis of cancer cells and to identify new therapeutic targets.


The professor Mancone collaborates with the anti-mafia magazine “I Siciliani Giovani” writing articles on the Italian university system.


tumor microenvironment

Gruppi di ricerca - Responsabile

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