| Titolo |
Pubblicato in |
Anno |
| The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance |
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH |
2024 |
| Clinical and Molecular Characterization of SMAD4 Splicing Variants in Patients with Juvenile Polyposis Syndrome |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
2024 |
| In Silico Deciphering of the Potential Impact of Variants of Uncertain Significance in Hereditary Colorectal Cancer Syndromes |
CELLS |
2024 |
| Exploring the Relationship of rs2802292 with Diabetes and NAFLD in a Southern Italian Cohort-Nutrihep Study |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
2024 |
| Methyltransferases in cancer drug resistance: unlocking the potential of targeting SMYD3 to sensitize cancer cells |
BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE |
2024 |
| Clinical assessment and genetic testing for hereditary polyposis syndromes in an Italian cohort of patients with colorectal polyps |
CANCERS |
2024 |
| Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models |
CELL & BIOSCIENCE |
2023 |
| Histone and DNA Methylation as Epigenetic Regulators of DNA Damage Repair in Gastric Cancer and Emerging Therapeutic Opportunities |
CANCERS |
2023 |
| SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage |
CELLS |
2023 |
| Tumor Testing and Genetic Analysis to Identify Lynch Syndrome Patients in an Italian Colorectal Cancer Cohort |
CANCERS |
2023 |
| SMYD3 Modulates the HGF/MET Signaling Pathway in Gastric Cancer |
CELLS |
2023 |
| Understanding the genetic landscape of pancreatic ductal adenocarcinoma to support personalized medicine: A systematic review |
CANCERS |
2023 |
| Classic galactosemia: clinical and computational characterization of a novel GALT missense variant (p.A303D) and a literature review |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
2023 |
| Identifying novel SMYD3 interactors on the trail of cancer hallmarks |
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL |
2022 |
| Discovery of the 4-aminopiperidine-based compound EM127 for the
site-specific covalent inhibition of SMYD3 |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
2022 |
| Identification and Somatic Characterization of the Germline PTEN Promoter Variant rs34149102 in a Family with Gastrointestinal and Breast Tumors |
GENES |
2022 |
| A novel STK11 gene mutation (c.388dupG, p.Glu130Glyfs∗33) in a Peutz-Jeghers family and evidence of higher gastric cancer susceptibility associated with alterations in STK11 region aa 107-170 |
GENES & DISEASES |
2022 |
| c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer |
CANCERS |
2022 |
| Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids |
CELL DEATH & DISEASE |
2021 |
| APC Splicing Mutations Leading to In-Frame Exon 12 or Exon
13 Skipping Are Rare Events in FAP Pathogenesis and Define
the Clinical Outcome |
GENES |
2021 |
