Katia De Marco | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH	2024
Clinical and Molecular Characterization of SMAD4 Splicing Variants in Patients with Juvenile Polyposis Syndrome	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2024
In Silico Deciphering of the Potential Impact of Variants of Uncertain Significance in Hereditary Colorectal Cancer Syndromes	CELLS	2024
Exploring the Relationship of rs2802292 with Diabetes and NAFLD in a Southern Italian Cohort-Nutrihep Study	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2024
Methyltransferases in cancer drug resistance: unlocking the potential of targeting SMYD3 to sensitize cancer cells	BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE	2024
Clinical assessment and genetic testing for hereditary polyposis syndromes in an Italian cohort of patients with colorectal polyps	CANCERS	2024
Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models	CELL & BIOSCIENCE	2023
Histone and DNA Methylation as Epigenetic Regulators of DNA Damage Repair in Gastric Cancer and Emerging Therapeutic Opportunities	CANCERS	2023
SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage	CELLS	2023
Tumor Testing and Genetic Analysis to Identify Lynch Syndrome Patients in an Italian Colorectal Cancer Cohort	CANCERS	2023
SMYD3 Modulates the HGF/MET Signaling Pathway in Gastric Cancer	CELLS	2023
Identifying novel SMYD3 interactors on the trail of cancer hallmarks	COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL	2022
Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2022
Identification and Somatic Characterization of the Germline PTEN Promoter Variant rs34149102 in a Family with Gastrointestinal and Breast Tumors	GENES	2022
A novel STK11 gene mutation (c.388dupG, p.Glu130Glyfs∗33) in a Peutz-Jeghers family and evidence of higher gastric cancer susceptibility associated with alterations in STK11 region aa 107-170	GENES & DISEASES	2022
c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer	CANCERS	2022
Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids	CELL DEATH & DISEASE	2021
APC Splicing Mutations Leading to In-Frame Exon 12 or Exon 13 Skipping Are Rare Events in FAP Pathogenesis and Define the Clinical Outcome	GENES	2021
Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality	ISCIENCE	2020