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stefano.gianni@uniroma1.it
Stefano Gianni
Professore Ordinario
Struttura:
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
E-mail:
stefano.gianni@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
The effect of proline cis‐trans isomerization on the folding of the C‐terminal SH2 domain from p85
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
Demonstration of binding induced structural plasticity in a sh2 domain
FRONTIERS IN MOLECULAR BIOSCIENCES
2020
Templated folding of intrinsically disordered proteins
THE JOURNAL OF BIOLOGICAL CHEMISTRY
2020
Understanding the binding induced folding of intrinsically disordered proteins by protein engineering: caveats and pitfalls
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein
PROTEIN SCIENCE
2020
Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2020
Understanding binding-induced folding by temperature jump
Methods in Molecular Biology
2020
Targeting the interaction between the SH3 domain of Grb2 and Gab2
CELLS
2020
Supertertiary protein structure affects an allosteric network
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2020
Investigating the molecular basis of the aggregation propensity of the pathological d76n mutant of beta-2 microglobulin: role of the denatured state
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019
Drug design and synthesis of first in class PDZ1 targeting NHERF1 inhibitors as anticancer agents
ACS MEDICINAL CHEMISTRY LETTERS
2019
The kinetics of folding of the NSH2 domain from p85
SCIENTIFIC REPORTS
2019
Characterization of human frataxin missense variants in cancer tissues
HUMAN MUTATION
2019
Mapping the allosteric network within a SH3 domain
SCIENTIFIC REPORTS
2019
Structural characterization of an on-pathway intermediate and transition state in the folding of the N-terminal SH2 domain from SHP2
THE FEBS JOURNAL
2019
Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
2019
A structurally heterogeneous transition state underlies coupled binding and folding of disordered proteins
THE JOURNAL OF BIOLOGICAL CHEMISTRY
2019
Seeking allosteric networks in PDZ domains
PROTEIN ENGINEERING, DESIGN & SELECTION
2019
Understanding intramolecular crosstalk in an intrinsically disordered protein
ACS CHEMICAL BIOLOGY
2019
β-catenin knockdown promotes nherf1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy
ONCOGENE
2018
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Progetti di Ricerca
Understanding and hijacking intrinsically disordered proteins in viral infection and cancer
Targeting the oncogenic signalling adaptor proteins CRKL, GAB2 and FRS2
Understanding the mechanism of recognition between Gab2 and its physiological partners
Investigating the role of protein disorder
Targeting SHP2 and Sos1 to block Noonan Syndrome
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