Ricerc@Sapienza

The research in my lab aims to dissect the epigenetic mechanisms governing muscle progenitor cells’ fate determination. We are interested in studying how histone modifying enzymes control stem cells’ alternative transcriptional programs and fates. We aim to reveal how these epigenetic players control skeletal muscle differentiation/regeneration, with the goal to understand how these processes are deregulated in muscle disorders, such as muscular dystrophies and malignancies of muscular origin as rhabdomyosarcomas