Michela Puxeddu

Pubblicazioni

Titolo Pubblicato in Anno
Metabolic Rewiring in Cancer: Small Molecule Inhibitors in Colorectal Cancer Therapy MOLECULES 2024
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2023
A Novel Validated UHPLC Method for the Estimation of Rosuvastatin and Its Complete Impurity Profile in Tablet Formulations MOLECULES 2023
Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators BIOORGANIC CHEMISTRY 2023
Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE 2023
Recent Advances in Drug Discovery for Triple-Negative Breast Cancer Treatment MOLECULES 2023
4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells JOURNAL OF MEDICINAL CHEMISTRY 2023
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor CANCERS 2022
Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor JOURNAL OF MEDICINAL CHEMISTRY 2022
Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2021
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme EUROPEAN JOURNAL OF PHARMACOLOGY 2021
Discovery of a novel class of norovirus inhibitors with high barrier of resistance PHARMACEUTICALS 2021
Emerging therapeutic agents for colorectal cancer MOLECULES 2021
Discovery of new 1,1'-biphenyl-4-sulfonamides as selective subnanomolar human carbonic anhydrase II inhibitors ACS MEDICINAL CHEMISTRY LETTERS 2020
Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2020
Discovery of Zika virus NS2B/NS3 inhibitors that prevent mice from fife-threatening infection and brain damage ACS MEDICINAL CHEMISTRY LETTERS 2020
Sulfonamide inhibitors of beta-Catenin signaling as anticancerAgents with different output on c-Myc CHEMMEDCHEM 2020
Targeting the interaction between the SH3 domain of Grb2 and Gab2 CELLS 2020

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