Marzia Perluigi

Pubblicazioni

Titolo Pubblicato in Anno
Redox imbalance and metabolic defects in the context of Alzheimer disease FEBS LETTERS 2024
Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease PHYSIOLOGICAL REVIEWS 2024
Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model NEUROBIOLOGY OF DISEASE 2024
Biliverdin reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β REDOX BIOLOGY 2024
Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer’s Disease ANTIOXIDANTS 2024
Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome AGING 2024
Intranasal administration of KYCCSRK peptide rescues brain insulin signaling activation and reduces Alzheimer’s disease-like neuropathology in a mouse model for Down syndrome ANTIOXIDANTS 2023
Chronic treatment with the anti-diabetic drug metformin rescues impaired brain mitochondrial activity and selectively ameliorates defective cognitive flexibility in a female mouse model of Rett syndrome NEUROPHARMACOLOGY 2023
GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control study EBIOMEDICINE 2023
Physical activity and neurotrophic factors as potential drivers of neuroplasticity in Parkinson's Disease: A systematic review and meta-analysis AGEING RESEARCH REVIEWS 2023
Aberrant protein networks in Alzheimer disease NATURE REVIEWS. NEUROLOGY 2022
CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down syndrome FREE RADICAL BIOLOGY & MEDICINE 2022
Role of Biliverdin Reductase A in the Regulation of Insulin Signaling in Metabolic and Neurodegenerative Diseases: An Update INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: a harmful synergistic path in down syndrome FREE RADICAL BIOLOGY & MEDICINE 2021
High-fat diet leads to reduced protein o-glcnacylation and mitochondrial defects promoting the development of alzheimer’s disease signatures INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles ALZHEIMER'S & DEMENTIA 2021
The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease FREE RADICAL BIOLOGY & MEDICINE 2021
mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder FREE RADICAL BIOLOGY & MEDICINE 2021
Building the future therapies for down syndrome: the third international conference of the T21 research society MOLECULAR SYNDROMOLOGY 2021
Oxidative stress and mTOR in Down syndrome brain: Link to Alzheimer’s dysmetabolism, neuropathology, and possible therapies FREE RADICAL BIOLOGY & MEDICINE 2021

Progetti di Ricerca

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