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dante.rotili@uniroma1.it
Dante Rotili
Professore Associato
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
dante.rotili@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Neuroprotective effects of PARP inhibitors in Drosophila models of Alzheimer’s disease
CELLS
2022
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2022
Sirtuin modulators: past, present, and future perspectives
FUTURE MEDICINAL CHEMISTRY
2022
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni
ACS INFECTIOUS DISEASES
2022
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5
JOURNAL OF MEDICINAL CHEMISTRY
2022
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells
CANCER GENE THERAPY
2022
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduced Viability in Worm Larval and Adult Stages
CHEMMEDCHEM
2022
Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics
MOLECULAR METABOLISM
2022
Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells
CANCER GENE THERAPY
2022
Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1
MICROORGANISMS
2022
Regulatory interplay between mir-181a-5p and estrogen receptor signaling cascade in breast cancer
CANCERS
2021
The two-faced role of sirt6 in cancer
CANCERS
2021
90Y-DOTA-nimotuzumab: Synthesis of a Promising β⁻ radiopharmaceutical
CURRENT RADIOPHARMACEUTICALS
2021
Sirt5 inhibition induces brown fat-like phenotype in 3t3-l1 preadipocytes
CELLS
2021
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2021
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53
JOURNAL OF MEDICINAL CHEMISTRY
2021
JQ1, inibitore delle proteine BET, riduce i fattori di virulenza e la patogenicità di Aspergillus fumigatus.
13° Congresso Nazionale della Società Italiana di Microbiologia Farmaceutica Obiettivi e Sfide della Microbiologia Moderna per la Difesa della Salute
2021
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions
CHEMICAL COMMUNICATIONS
2021
Emerging Therapeutic Potential of SIRT6 Modulators
JOURNAL OF MEDICINAL CHEMISTRY
2021
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression
GASTROENTEROLOGY
2021
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Progetti di Ricerca
Modulators of epigenetic targets for the treatment of parasitic diseases.
Development of novel LSD1 inhibitors as potential new generation anticancer agents.
Development of glucose-based pure beta minus radiotracers potentially suitable for tumor radioguided surgery.
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