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Dante.Rotili@uniroma1.it
Dante Rotili
Professore Associato
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
Dante.Rotili@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Effect of α-methoxy substitution on the anti-HIV activity of dihydropyrimidin-4(3 H)-ones
JOURNAL OF MEDICINAL CHEMISTRY
2019
Sirtuins as drug targets
Epigenetic Drug Discovery
2019
Gold nanoparticles and nanorods in nuclear medicine: a mini review
APPLIED SCIENCES
2019
Enzymatic and biological characterization of novel sirtuin modulators against cancer
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019
Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2)
JOURNAL OF MEDICINAL CHEMISTRY
2019
Epigenetic polypharmacology: a new frontier for epi-drug discovery
MEDICINAL RESEARCH REVIEWS
2019
α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors
ACS MEDICINAL CHEMISTRY LETTERS
2019
DNA Methylation: Biological Implications and Modulation of Its Aberrant Dysregulation
The DNA, RNA, and Histone Methylomes
2019
Inhibition of histone demethylases LSD1 and UTX regulates ERα signaling in breast cancer
CANCERS
2019
Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
CLINICAL EPIGENETICS
2019
Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells
EUROPEAN JOURNAL OF PHARMACOLOGY
2019
Effects of glutathione transferase-targeting nitrobenzoxadiazole compounds in relation to PD-L1 status in human melanoma cells
CHEMOTHERAPY
2019
H19-dependent transcriptional regulation of β3 and β4 integrins upon estrogen and hypoxia favors metastatic potential in prostate cancer
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019
Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2019
Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors
Topics in Medicinal Chemistry
2019
Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
2018
RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer
CLINICAL CANCER RESEARCH
2018
Mass spectrometry characterization of DOTA-Nimotuzumab conjugate as precursor of an innovative β − tracer suitable in radio-guided surgery
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2018
KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2
CLINICAL EPIGENETICS
2018
Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications
FUTURE MEDICINAL CHEMISTRY
2018
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Progetti di Ricerca
Modulators of epigenetic targets for the treatment of parasitic diseases.
Development of novel LSD1 inhibitors as potential new generation anticancer agents.
Development of glucose-based pure beta minus radiotracers potentially suitable for tumor radioguided surgery.
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