| Titolo |
Pubblicato in |
Anno |
| Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity |
JOURNAL OF MEDICINAL CHEMISTRY |
2024 |
| Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer |
CANCER CELL INTERNATIONAL |
2024 |
| Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells |
CHEMMEDCHEM |
2024 |
| A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection |
PLOS BIOLOGY |
2024 |
| The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases |
CELLULAR AND MOLECULAR LIFE SCIENCES |
2024 |
| (Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling |
ACS INFECTIOUS DISEASES |
2024 |
| M6A reduction relieves FUS-associated ALS granules |
NATURE COMMUNICATIONS |
2024 |
| STRUCTURE-BASED MECHANISM OF RIBOREGULATION OF THE METABOLIC ENZYME SHMT1 |
MOLECULAR CELL |
2024 |
| Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development |
PHARMACEUTICALS |
2024 |
| Off-target inhibition of human dihydroorotate dehydrogenase (hDHODH) highlights challenges in the development of fat mass and obesity-associated protein (FTO) inhibitors |
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE |
2024 |
| Activation and inhibition of sirtuins: From bench to bedside |
MEDICINAL RESEARCH REVIEWS |
2024 |
| Successes and challenges in the development of BD1-selective BET inhibitors: a patent review |
EXPERT OPINION ON THERAPEUTIC PATENTS |
2024 |
| GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis |
BRAIN, BEHAVIOR, AND IMMUNITY |
2024 |
| Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
2023 |
| Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence |
JOURNAL OF MEDICINAL CHEMISTRY |
2023 |
| METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey |
JOURNAL OF MEDICINAL CHEMISTRY |
2023 |
| Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells |
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
2023 |
| GreenMedChem- the challenge in the next decade toward eco-friendly compounds and processes in drug design |
GREEN CHEMISTRY |
2023 |
| Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery |
CELLS |
2023 |
| Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII |
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
2023 |
