| Titolo |
Pubblicato in |
Anno |
| Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma. |
SCIENTIFIC REPORTS |
2017 |
| Development of 1,2,4-oxadiazoles as potent and selective inhibitors of the human deacetylase sirtuin 2: structure-activity relationship, X-ray crystal structure, and anticancer activity |
JOURNAL OF MEDICINAL CHEMISTRY |
2017 |
| Y3+ embedded in polymeric nanoparticles: Morphology, dimension and stability of composite colloidal system |
COLLOIDS AND SURFACES. A, PHYSICOCHEMICAL AND ENGINEERING ASPECTS |
2017 |
| Feasibility of beta-particle radioguided surgery for a variety of “nuclear medicine” radionuclides |
PHYSICA MEDICA |
2017 |
| The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor. |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
2017 |
| Lysine deacetylase inhibitors in parasites: past, present, and future perspectives. |
JOURNAL OF MEDICINAL CHEMISTRY |
2017 |
| Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features. |
NATURE COMMUNICATIONS |
2017 |
| Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma |
SCIENTIFIC REPORTS |
2017 |
| c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition |
JOURNAL OF TRANSLATIONAL MEDICINE |
2016 |
| Sirtuin functions and modulation: from chemistry to the clinic |
CLINICAL EPIGENETICS |
2016 |
| Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells |
AMERICAN JOURNAL OF CANCER RESEARCH |
2016 |
| Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells |
ONCOTARGET |
2016 |
| The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases |
BIOCHEMICAL PHARMACOLOGY |
2016 |
| At long last potent and selective KDM5 inhibitors |
CELL CHEMICAL BIOLOGY |
2016 |
| Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features |
SCIENCE ADVANCES |
2016 |
| Synthesis and structure-activity relationship of new cytotoxic agents targeting human glutathione-S-transferases. |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
2015 |
| Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells. |
MEDCHEMCOMM |
2015 |
| Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells |
JOURNAL OF MEDICINAL CHEMISTRY |
2015 |
| SIRT5 regulation of ammonia-induced autophagy and mitophagy |
AUTOPHAGY |
2015 |
| Enzyme kinetics and inhibition of histone acetyltransferase KAT8 |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
2015 |
