Isabella Screpanti | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
NOTCH1 is aberrantly activated in chronic lymphocytic leukemia hematopoietic stem cells	FRONTIERS IN ONCOLOGY	2018
Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagation.	ONCOGENE	2018
The Notch3 receptor and its intracellular signaling-dependent oncogenic mechanisms	Molecular Mechanisms of Notch Signaling	2018
Notch and NF-kB: Coach and Players of Regulatory T-Cell Resposnse in Cancer	FRONTIERS IN IMMUNOLOGY	2018
Notch3 and CXCR4 cross-signaling sustains acute T-cell leukemia progression	ESMO OPEN	2018
Brain Targeting by Liposome-Biomolecular Corona Boosts Anticancer Efficacy of Temozolomide in Glioblastoma Cells	ACS CHEMICAL NEUROSCIENCE	2018
Potential targeted therapy for T-cell acute lymphoblastic leukemia: perturbing ER/UPR signaling via Notch3 down-regulation	Cell communication and signaling: how to turn bad language into positive one	2018
IL-4-dependent Jagged1 expression/processing is associated with survival of chronic lymphocytic leukemia cells but not with Notch activation	CELL DEATH & DISEASE	2018
Manipulation of lipoplex concentration at the cell surface boosts transfection efficiency in hard-to-transfect cells	NANOMEDICINE	2017
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.	SCIENTIFIC REPORTS	2017
Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma	ONCOGENE	2017
PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma	ONCOGENE	2017
The mazy case of Notch and immunoregulatory cells	JOURNAL OF LEUKOCYTE BIOLOGY	2017
Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia	SCIENTIFIC REPORTS	2017
Maml1 acts cooperatively with Gli proteins to regulate Sonic hedgheog signaling pathway	CELL DEATH & DISEASE	2017
Cytotoxic activity of Juglone against Notch3-overexpressing T-cell acute lymphoblastic leukemia: targeting the ER/UPR signaling	Notch meeting X	2017
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells	BMC CANCER	2017
Optimizing the identification of risk-relevant mutations by multigene panel testing in selected hereditary breast/ovarian cancer families	CANCER MEDICINE	2017
Loss of miR-107, miR-181c and miR-29a-3p promote activation of Notch2 signaling in pediatric high-grade gliomas (pHGGs)	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2017
Role of Notch3 in sustaining UPR signaling in Notch3-overexpressing T-cell acute lymphoblastic leukemia.	Atti del SIPMeT "Young Scientist Meeting"	2017

Progetti di Ricerca

From thymocyte egression to T-cell Acute Lymphoblastic Leukemia development: identification of new targets for T-ALL therapy