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rosamaria.orlando@uniroma1.it
Rosamaria Orlando
Ricercatore
Struttura:
DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER"
E-mail:
rosamaria.orlando@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Preclinical and clinical study on type 3 metabotropic glutamate receptors in Parkinson's disease
NPJ PARKINSON'S DISEASE
2025
Metabotropic Glutamate Receptors Type 3 and 5 Feature the “NeuroTransmitter-type” of Glioblastoma: A Bioinformatic Approach
CURRENT NEUROPHARMACOLOGY
2024
GPCR interactions involving metabotropic glutamate receptors and their relevance to the pathophysiology and treatment of CNS disorders
NEUROPHARMACOLOGY
2023
Blunted type-5 metabotropic glutamate receptor-mediated polyphosphoinositide hydrolysis in two mouse models of monogenic autism
NEUROPHARMACOLOGY
2023
Changes in mGlu5 Receptor Signaling Are Associated with Associative Learning and Memory Extinction in Mice
LIFE
2022
Synergic action of L-acetylcarnitine and L-methylfolate in Mouse Models of Stress-Related Disorders and Human iPSC-Derived Dopaminergic Neurons
FRONTIERS IN PHARMACOLOGY
2022
mGlu3 receptor regulates microglial cell reactivity in neonatal rats
JOURNAL OF NEUROINFLAMMATION
2021
The bacterial quorum sensing molecule, 2-heptyl-3-hydroxy-4-quinolone (PQS), inhibits signal transduction mechanisms in brain tissue and is behaviorally active in mice
PHARMACOLOGICAL RESEARCH
2021
MGlu3 receptor regulates microglial cell reactivity in neonatal rats.
JOURNAL OF NEUROINFLAMMATION
2021
Targeting mGlu receptors for optimization of antipsychotic activity and disease-modifying effect in schizophrenia
FRONTIERS IN PSYCHIATRY
2019
Targeting mGlu Receptors for Optimization of Antipsychotic Activity and Disease-Modifying Effect in Schizophrenia
FRONTIERS IN PSYCHIATRY
2019
Targeting metabotropic glutamate receptors in the treatment of primary brain tumors
CURRENT OPINION IN PHARMACOLOGY
2018
Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system
NEUROPHARMACOLOGY
2018
Targeting mGlu5 metabotropic glutamate receptors in the treatment of cognitive dysfunction in a mouse model of phenylketonuria
FRONTIERS IN NEUROSCIENCE
2018
Stress as risk factor for Alzheimer's disease
PHARMACOLOGICAL RESEARCH
2018
In vivo non-radioactive assessment of mGlu5 receptor-activated polyphosphoinositide hydrolysis in response to systemic administration of a positive allosteric modulator.
FRONTIERS IN PHARMACOLOGY
2018
Targeting metabotropic glutamate receptors in the treatment of primary brain tumors
CURRENT OPINION IN PHARMACOLOGY
2018
Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus
PHARMACOLOGICAL RESEARCH
2017
Type-7 metabotropic glutamate receptors negatively regulate α1-adrenergic receptor signalling
NEUROPHARMACOLOGY
2017
Type-7 metabotropic glutamate receptors negatively regulate α1-adrenergic receptor signalling
NEUROPHARMACOLOGY
2017
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Progetti di Ricerca
Ruolo dei recettori metabotropici per il glutammato mGlu3 e mGlu5 nel processo di maturazione e differenziamento funzionale degli oligodendrociti e nel danno alla mielina durante le fasi precoci dello sviluppo postnatale
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