| Titolo | Pubblicato in | Anno |
|---|---|---|
| Microglia complement signaling promotes neuronal elimination and normal brain functional connectivity | CEREBRAL CORTEX | 2023 |
| Microglia complement signaling promotes neuronal elimination and normal brain functional connectivity | CEREBRAL CORTEX | 2023 |
| Role of HSV-1 in Alzheimer's disease pathogenesis. A challenge for novel preventive/therapeutic strategies | CURRENT OPINION IN PHARMACOLOGY | 2022 |
| Nitrostilbenes. Synthesis and biological evaluation as potential anti-influenza virus agents | PHARMACEUTICALS | 2022 |
CURRENT POSITION
01/02/2024 - 01/02/2025: Postdoc position
Location: Institute of Translational Pharmacology (IFT), National Research Council (CNR), Rome.
Project: "EARLY AND LONG-TERM BRAIN DAMAGE CAUSED BY RECURRENT HSV-1 INFECTION"
Supervisor: Dr. Giovanna De Chiara
EDUCATION AND TRAINING
01/11/2020 - 31/01/2024: PhD in Infectious Diseases, Microbiology, and Public Health (36th cycle)
Location: Sapienza University of Rome, Department of Infectious Diseases and Public Health
Thesis Defense: 22/04/2024
Thesis Title: "HSV-1 INDUCES COMPLEMENT ACTIVATION IN BRAIN CELLS: POSSIBLE TRIGGER OF SYNAPTIC DEFICITS"
Grade: Excellent with Honors
Supervisor: Prof. Anna Teresa Palamara
My PhD research showed evidence of a novel mechanism that may underlie synaptic damage induced by herpes simplex virus-1 (HSV-1) in primary murine neuronal cells. My studies demonstrated how HSV-1 infection in primary neurons triggers the classical complement cascade, which cooperates with microglia to phagocytose virus-damaged synapses.
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