Rosa Molfetta

Pubblicazioni

Titolo Pubblicato in Anno
The Controversial Role of Intestinal Mast Cells in Colon Cancer CELLS 2023
NKG2D engagement on human NK cells leads to DNAM‐1 hypo‐responsiveness through different converging mechanisms EUROPEAN JOURNAL OF IMMUNOLOGY 2023
Impact on NK cell functions of acute versus chronic exposure to extracellular vesicle-associated MICA. Dual role in cancer immunosurveillance JOURNAL OF EXTRACELLULAR VESICLES 2022
NK Cells and Other Cytotoxic Innate Lymphocytes in Colorectal Cancer Progression and Metastasis INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Immunomodulatory effect of NEDD8-activating enzyme inhibition in Multiple Myeloma: upregulation of NKG2D ligands and sensitization to Natural Killer cell recognition CELL DEATH & DISEASE 2021
Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation EUROPEAN JOURNAL OF IMMUNOLOGY 2021
Immune complexes exposed on mast cell-derived nanovesicles amplify allergic inflammation ALLERGY 2020
CD155: a multi-functional molecule in tumor progression INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Bone marrow stromal cell-derived IL-8 upregulates PVR expression on multiple myeloma cells via NF-kB transcription factor CANCERS 2020
FcepsilonRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Samhd1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity PLOS PATHOGENS 2020
The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing. EUROPEAN JOURNAL OF IMMUNOLOGY 2019
The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in multiple myeloma. modulation by bromodomain and Extra-Terminal (BET) protein inhibitors CELL DEATH & DISEASE 2019
Activation of liver X receptor up-regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms THE FASEB JOURNAL 2019
Post-translational mechanisms regulating NK cell activating receptors and their ligands in cancer: Potential targets for therapeutic intervention FRONTIERS IN IMMUNOLOGY 2019
NKG2D and its ligands: one for all, all for one FRONTIERS IN IMMUNOLOGY 2018
Translating the anti-myeloma activity of Natural Killer cells into clinical application CANCER TREATMENT REVIEWS 2018
Abnormal regulation of BCR signalling by c-Cbl in chronic lymphocytic leukaemia ONCOTARGET 2018
p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells ONCOIMMUNOLOGY 2017
Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: role of HSP70/TLR2/NF-kB axis ONCOIMMUNOLOGY 2017

ERC

  • LS1
  • LS1_9

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Ruolo delle cellule dell'immunità innata nella progressione tumorale, in particolare del cancro del colon-retto.

Meccanismi regolazione dell'espressione e della funzione di recettori dell'immunità innata.

Ruolo delle vescicole extracellulari nella comunicazione tra cellule.

Keywords

Immunology
anti-tumor immune response
innate immune cells

Progetti di Ricerca

Laboratori di ricerca

IMMUNOLOGIA MOLECOLARE E IMMUNOPATOLOGIA 3 -317, 322

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