Angelo Toto

Pubblicazioni

Titolo Pubblicato in Anno
Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains THE JOURNAL OF BIOLOGICAL CHEMISTRY 2023
Different electrostatic forces drive the binding kinetics of SARS-CoV, SARS-CoV-2 and MERS-CoV Envelope proteins with the PDZ2 domain of ZO1 SCIENTIFIC REPORTS 2023
Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators BIOORGANIC CHEMISTRY 2023
Monomeric and dimeric states of human ZO1-PDZ2 are functional partners of the SARS-CoV-2 E protein COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL 2023
Biophysical Characterization of the Binding Mechanism between the MATH Domain of SPOP and Its Physiological Partners INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
An intramolecular energetic network regulates ligand recognition in a SH2 domain PROTEIN SCIENCE 2023
Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 2023
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor CANCERS 2022
On the effects of disordered tails, supertertiary structure and quinary interactions on the folding and function of protein domains BIOMOLECULES 2022
Characterization of early and late transition states of the folding pathway of a SH2 domain PROTEIN SCIENCE 2022
Folding and binding mechanisms of the SH2 domain from Crkl BIOMOLECULES 2022
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat PROTEIN SCIENCE 2022
Exploring the effect of tethered domains on the folding of Grb2 protein ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 2022
The cooperative folding of annexin A2 relies on a transient nonnative intermediate BIOPHYSICAL JOURNAL 2022
SH2 Domains: Folding, Binding and Therapeutical Approaches INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Double mutant cycles as a tool to address folding, binding, and allostery INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Folding and misfolding of a PDZ tandem repeat JOURNAL OF MOLECULAR BIOLOGY 2021
Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL 2021
Probing the effects of local frustration in the folding of a multidomain protein JOURNAL OF MOLECULAR BIOLOGY 2021
Determining folding and binding properties of the C-terminal SH2 domain of SHP2 PROTEIN SCIENCE 2021

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