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angelo.toto@uniroma1.it
Angelo Toto
Ricercatore
Struttura:
DIPARTIMENTO DI SCIENZE BIOCHIMICHE "ALESSANDRO ROSSI FANELLI"
E-mail:
angelo.toto@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains
THE JOURNAL OF BIOLOGICAL CHEMISTRY
2023
Different electrostatic forces drive the binding kinetics of SARS-CoV, SARS-CoV-2 and MERS-CoV Envelope proteins with the PDZ2 domain of ZO1
SCIENTIFIC REPORTS
2023
Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators
BIOORGANIC CHEMISTRY
2023
Monomeric and dimeric states of human ZO1-PDZ2 are functional partners of the SARS-CoV-2 E protein
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
2023
Biophysical Characterization of the Binding Mechanism between the MATH Domain of SPOP and Its Physiological Partners
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023
An intramolecular energetic network regulates ligand recognition in a SH2 domain
PROTEIN SCIENCE
2023
Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
2023
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor
CANCERS
2022
On the effects of disordered tails, supertertiary structure and quinary interactions on the folding and function of protein domains
BIOMOLECULES
2022
Characterization of early and late transition states of the folding pathway of a SH2 domain
PROTEIN SCIENCE
2022
Folding and binding mechanisms of the SH2 domain from Crkl
BIOMOLECULES
2022
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat
PROTEIN SCIENCE
2022
Exploring the effect of tethered domains on the folding of Grb2 protein
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
2022
The cooperative folding of annexin A2 relies on a transient nonnative intermediate
BIOPHYSICAL JOURNAL
2022
SH2 Domains: Folding, Binding and Therapeutical Approaches
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
Double mutant cycles as a tool to address folding, binding, and allostery
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
Folding and misfolding of a PDZ tandem repeat
JOURNAL OF MOLECULAR BIOLOGY
2021
Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
2021
Probing the effects of local frustration in the folding of a multidomain protein
JOURNAL OF MOLECULAR BIOLOGY
2021
Determining folding and binding properties of the C-terminal SH2 domain of SHP2
PROTEIN SCIENCE
2021
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