Roberta Misasi

Pubblicazioni

Titolo Pubblicato in Anno
Proteome data of neuroblastoma cells overexpressing Neuroglobin DATA IN BRIEF 2022
Editorial for special Issue: neuroglobin from brain protection to cancer progression CELLS 2022
The role of cardiolipin as a scaffold mitochondrial phospholipid in autophagosome formation: In vitro evidence BIOMOLECULES 2021
Targeting Lipid Rafts as a Strategy Against Coronavirus FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2021
Protein aggregation landscape in neurodegenerative diseases: clinical relevance and future applications INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Effect of Heparanase inhibitor on Tissue Factor overexpression in platelets and endothelial cells induced by anti-β2-GPI antibodies JOURNAL OF THROMBOSIS AND HAEMOSTASIS 2021
Anti-vimentin/cardiolipin IgA in the antiphospholipid syndrome: a new tool for “seronegative” diagnosis CLINICAL AND EXPERIMENTAL IMMUNOLOGY 2021
Role of erlins in the control of cell fate through lipid rafts CELLS 2021
Overexpression of neuroglobin promotes energy metabolism and autophagy induction in human neuroblastoma SH-SY5Y cells CELLS 2021
Anti-Inflammatory Activity of a CB2 Selective Cannabinoid Receptor Agonist: Signaling and Cytokines Release in Blood Mononuclear Cells MOLECULES 2021
“Non-criteria antiphospholipid antibodies”: bridging the gap between seropositive and seronegative Antiphospholipid Syndrome RHEUMATOLOGY 2021
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) AUTOPHAGY 2021
Editorial: Targeting Lipid Rafts as a Strategy Against Infection and Cancer FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2021
Neuritogenic signal pathway of tPA mediated by the multimolecular complex containing PrPC and LRP1 is dependent on lipid rafts THE FASEB JOURNAL 2020
LRP6 mediated signal transduction pathway triggered by tissue plasminogen activator acts through lipid rafts in neuroblastoma cells JOURNAL OF CELL COMMUNICATION AND SIGNALING 2020
A multimolecular signaling complex including PrPC and LRP1 is strictly dependent on lipid rafts and is essential for the function of tissue plasminogen activator JOURNAL OF NEUROCHEMISTRY 2020
Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs AUTOPHAGY 2020
Molecular mechanisms of “antiphospholipid antibodies” and their paradoxical role in the pathogenesis of “seronegative APS” INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Tissue factor over-expression in platelets of patients with anti-phospholipid syndrome: induction role of anti-β2-GPI antibodies CLINICAL AND EXPERIMENTAL IMMUNOLOGY 2019
Reduction of autophagy and increase in apoptosis correlates with a favorable clinical outcome in patients with rheumatoid arthritis treated with anti-TNF drugs ARTHRITIS RESEARCH & THERAPY 2019

ERC

  • LS1_1
  • LS1_5
  • LS1_9
  • LS3_2
  • LS3_5
  • LS5_11
  • LS6_4

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

  1. Ruolo dei “rafts” lipidici sulle proprietà biochimiche, biofisiche e immunologiche della membrana plasmatica cellulare, inclusa la trasduzione di segnale.
  2. Ciclo vita/morte della cellula: Meccanismi molecolari in Autofagia e Apoptosi.
  3. Neurodegenerazione e fattori neuroprotettivi (Neuroglobina, Prosaposina).
  4. Significato biologico e clinico degli anticorpi anti-fosfolipidi e delle modificazioni post-traduzionali in patologia autoimmunitarie.

Keywords

Lipid rafts
Neuroglobin
autophagy
apoptosis
Seronegative anti-phospholipid syndrome
anti-phospholipid antibodies

Progetti di Ricerca

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