Deborah Quaglio | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma	EXPERT OPINION ON THERAPEUTIC TARGETS	2020
Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells	CELL DEATH DISCOVERY	2020
Alvaxanthone, a thymidylate synthase inhibitor with nematocidal and tumoricidal activities	MOLECULES	2020
Chalcones and chalcone-mimetic derivatives as Notch inhibitors in a model of T-cell Acute Lymphoblastic Leukemia	ACS MEDICINAL CHEMISTRY LETTERS	2019
IR ion spectroscopy in a combined approach with MS/MS and IM-MS to discriminate epimeric anthocyanin glycosides (cyanidin 3-O-glucoside and -galactoside)	INTERNATIONAL JOURNAL OF MASS SPECTROMETRY	2019
Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells	SCIENTIFIC REPORTS	2019
Nigritanine as a new potential antimicrobial alkaloid for the treatment of staphylococcus aureus-induced infections	TOXINS	2019
A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth	CANCERS	2019
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma	CELL COMMUNICATION AND SIGNALING	2019
NMR for sample quality assessment in metabolomics	NEW BIOTECHNOLOGY	2019
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61	JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY	2018
Synthesis of bromoundecyl resorc[4]arenes and applications of the cone stereoisomer as selector for liquid chromatography	JOURNAL OF ORGANIC CHEMISTRY	2018
Olefin metathesis reaction as a locking tool for macrocycle and mechanomolecule construction	ORGANIC CHEMISTRY FRONTIERS	2018
Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia	SCIENTIFIC REPORTS	2017
First Detection of a Ruthenium-Carbene-Resorc[4]arene Complex During the Progress of a Metathesis Reaction	EUROPEAN JOURNAL OF ORGANIC CHEMISTRY	2017
Occurrence of enantioselectivity in nature: The case of (S)-norcoclaurine	CHIRALITY	2016
The Pictet-Spengler Reaction Still On Stage	CURRENT PHARMACEUTICAL DESIGN	2016
Molecular recognition of natural products by resorc[4]arene receptors	CURRENT PHARMACEUTICAL DESIGN	2016
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype	CELL DEATH & DISEASE	2016
Resorc[4]arenes as preorganized synthons for surface recognition and host-guest chemistry	Calixarenes and Beyond	2016

ERC

PE5_17
PE5_23

KET

Advanced materials
Life-science technologies & biotechnologies

Interessi di ricerca

Preparazione di recettori artificiali a struttura resorc[4]arenica per lo sviluppo di immunosensori;
Sintesi di composti naturali ad attività antitumorale;
Sintesi di linker poliamminici per il delivery attivo di farmaci ad attività antitumorale.

Gruppi di ricerca

SYNLAB