Maria Carmela Bonaccorsi Di Patti


Titolo Pubblicato in Anno
Experimental-theoretical study of laccase as a detoxifier of aflatoxins SCIENTIFIC REPORTS 2023
Iron saturation drives lactoferrin effects on oxidative stress and neurotoxicity induced by HIV-1 tat INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Membrane transporters involved in iron trafficking: physiological and pathological aspects. BIOMOLECULES 2023
Genetic incorporation of dansylalanine in human ferroportin to probe the alternating access mechanism of iron transport INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Editorial: Understanding membrane transporters: from structure to function FRONTIERS IN MOLECULAR BIOSCIENCES 2023
Lactoferrin, the Moonlighting Protein of Innate Immunity INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Synuclein Analysis in Adult Xenopus laevis INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
New Inhibitors of the Human p300/CBP Acetyltransferase Are Selectively Active against the Arabidopsis HAC Proteins INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Editorial. Nutraceuticals. New perspectives and approaches in human health and disease FRONTIERS IN PHARMACOLOGY 2022
Lactoferrin binding to SARS-CoV-2 Spike glycoprotein blocks pseudoviral entry and relieves iron protein dysregulation in several in vitro models PHARMACEUTICS 2022
Lactoferrin. From the structure to the functional orchestration of iron homeostasis BIOMETALS 2022
Biophysical characterization of the complex between the iron-responsive transcription factor Fep1 and DNA EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 2021
Host - Bacterial Pathogen Communication: The Wily Role of the Multidrug Efflux Pumps of the MFS Family FRONTIERS IN MOLECULAR BIOSCIENCES 2021
Production of recombinant human ceruloplasmin: Improvements and perspectives INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Analysis of role of aromatic residues in extracellular loop 2 of Prokineticin receptor 2 in ligand binding probed with genetically encoded photo-crosslinkers BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 2021
Native and iron-saturated bovine lactoferrin differently hinder migration in a model of human glioblastoma by reverting epithelial-to-mesenchymal transition-like process and inhibiting interleukin-6/STAT3 axis CELLULAR SIGNALLING 2020
Lactoferrin's anti-cancer properties. Safety, selectivity, and wide range of action BIOMOLECULES 2020
Dynamical behavior of the human ferroportin homologue from Bdellovibrio bacteriovorus: Insight into the ligand recognition mechanism INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Isoforms of the DHTKD1-encoded 2-oxoadipate dehydrogenase, identified in animal tissues, are not observed upon the human DHTKD1 expression in bacterial or yeast systems BIOCHEMISTRY 2020
Lactoferrin in the prevention and treatment of intestinal inflammatory pathologies associated with colorectal cancer development CANCERS 2020


  • LS1
  • LS1_2
  • LS1_4


  • Life-science technologies & biotechnologies

Interessi di ricerca

1) Studio strutturale e funzionale di proteine coinvolte nella traslocazione del ferro attraverso le membrane negli eucarioti, con particolare attenzione alle ossidasi blu multinucleari a rame e alle permeasi.

2) Studio strutturale e funzionale del fattore trascrizionale responsivo al ferro Fep1 del lievito metilotrofico Pichia pastoris.

3) Studio dell'azione della lattoferrina nella regolazione dell'omeostasi del ferro, nella neurodegenerazione e nell'infiammazione.


Membrane Proteins
iron metabolism

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