| Titolo |
Pubblicato in |
Anno |
| Potential of a natural compound as Hedgehog pathway inhibitor for the treatment of Intrahepatic Cholangiocarcinoma |
30° CONGRESSO NAZIONALE DELLE MALATTIE DIGESTIVE |
2024 |
| New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer |
BIOORGANIC CHEMISTRY |
2024 |
| MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation |
ONCOGENE |
2024 |
| Dissecting the hindrance of Hedgehog pathway in Intrahepatic Cholangiocarcinoma: a step towards targeted therapy |
UNITED EUROPEAN GASTROENTEROLOGY JOURNALUNITED EUROPEAN GASTROENTEROLOGY JOURNAL |
2024 |
| SMURF1 and SMURF2 directly target GLI1 for ubiquitination and proteasome-dependent degradation |
CELL DEATH DISCOVERY |
2024 |
| Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation |
CANCER LETTERS |
2023 |
| KCTD1 is a new modulator of the KCASH family of Hedgehog suppressors |
NEOPLASIA |
2023 |
| Exploring the potential of anthraquinone-based hybrids for identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour |
CHEMISTRY |
2023 |
| SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma |
CELL DEATH AND DIFFERENTIATION |
2023 |
| ERAP1 as an emerging therapeutic target for medulloblastoma |
TRENDS IN CANCER |
2022 |
| Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors? |
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY |
2022 |
| A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma |
NEUROPATHOLOGY & APPLIED NEUROBIOLOGY |
2022 |
| Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma |
CANCER LETTERS |
2021 |
| Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors |
CHEMISTRY-A EUROPEAN JOURNAL |
2021 |
| Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis |
FRONTIERS IN MOLECULAR NEUROSCIENCE |
2021 |
| SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples |
ELIFE |
2021 |
| Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma |
FRONTIERS IN CHEMISTRY |
2021 |
| A new smoothened antagonist bearing the purine scaffold shows antitumour activity in vitro and in vivo |
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
2021 |
| Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module |
CELL REPORTS |
2020 |
| The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i |
CANCERS |
2020 |
