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lucia.dimarcotullio@uniroma1.it
Lucia Di Marcotullio
Professore Ordinario
Struttura:
DIPARTIMENTO DI MEDICINA MOLECOLARE
E-mail:
lucia.dimarcotullio@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Potential of a natural compound as Hedgehog pathway inhibitor for the treatment of Intrahepatic Cholangiocarcinoma
30° CONGRESSO NAZIONALE DELLE MALATTIE DIGESTIVE
2024
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation
CANCER LETTERS
2023
KCTD1 is a new modulator of the KCASH family of Hedgehog suppressors
NEOPLASIA
2023
Exploring the potential of anthraquinone-based hybrids for identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour
CHEMISTRY
2023
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma
CELL DEATH AND DIFFERENTIATION
2023
ERAP1 as an emerging therapeutic target for medulloblastoma
TRENDS IN CANCER
2022
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors?
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2022
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma
NEUROPATHOLOGY & APPLIED NEUROBIOLOGY
2022
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma
CANCER LETTERS
2021
Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors
CHEMISTRY-A EUROPEAN JOURNAL
2021
Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis
FRONTIERS IN MOLECULAR NEUROSCIENCE
2021
SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples
ELIFE
2021
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma
FRONTIERS IN CHEMISTRY
2021
A new smoothened antagonist bearing the purine scaffold shows antitumour activity in vitro and in vivo
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module
CELL REPORTS
2020
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i
CANCERS
2020
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present)
EXPERT OPINION ON THERAPEUTIC PATENTS
2020
Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth
MOLECULAR ONCOLOGY
2020
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation
CELL DEATH & DISEASE
2020
Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors
CANCER IMMUNOLOGY RESEARCH
2020
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Progetti di Ricerca
Oncogenic role of the aminopeptidase ERAP1 in Hedgehog-dependent cancer
Laboratori di ricerca
IMAGING FUNZIONALE IN VIVO
LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 202
LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 220 221
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