Lucia Di Marcotullio

Pubblicazioni

Titolo Pubblicato in Anno
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation CANCER LETTERS 2023
ERAP1 as an emerging therapeutic target for medulloblastoma TRENDS IN CANCER 2022
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors? FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2022
A gene dosage‐dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH‐medulloblastoma NEUROPATHOLOGY & APPLIED NEUROBIOLOGY 2022
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma CANCER LETTERS 2021
Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors CHEMISTRY-A EUROPEAN JOURNAL 2021
Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis FRONTIERS IN MOLECULAR NEUROSCIENCE 2021
SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples ELIFE 2021
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma FRONTIERS IN CHEMISTRY 2021
A new smoothened antagonist bearing the purine scaffold shows antitumour activity in vitro and in vivo INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module CELL REPORTS 2020
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i CANCERS 2020
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present) EXPERT OPINION ON THERAPEUTIC PATENTS 2020
Downregulation of miR-326 and its host gene β-arrestin1 induces pro survival activity of E2F1 and promotes medulloblastoma growth MOLECULAR ONCOLOGY 2020
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation CELL DEATH & DISEASE 2020
Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors CANCER IMMUNOLOGY RESEARCH 2020
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma EXPERT OPINION ON THERAPEUTIC TARGETS 2020
Dual smo/braf inhibition by flavonolignans from silybum marianum† ANTIOXIDANTS 2020
Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer CANCERS 2020
Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation INTERNATIONAL JOURNAL OF ONCOLOGY 2019

Progetti di Ricerca

Laboratori di ricerca

IMAGING FUNZIONALE IN VIVO
LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 202
LABORATORIO BIOCHIMICO BIOLOGICO LIV BIOSICUREZZA 1 220 221

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