Esterina Pascale | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Exploring miRNAs' based modeling approach for predicting PIRA in multiple sclerosis. A comprehensive analysis	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2024
How can CpG methylations, and pair-to-pair correlations between the main (gene) and the opposite strands, suggest a bending DNA loop. Insights into the 5′-UTR of DAT1	GENES	2023
Methylation Dynamics on 5′-UTR of DAT1 Gene as a Bio-Marker to Recognize Therapy Success in ADHD Children	CHILDREN	2023
DAT1 5′-Un-Translated-Region methylation patterns as bio-markers of ADHD psycho-pathology. Contribution to disease prognosis and to monitoring of a successful therapy	BIOMEDICINES	2023
Cladribine and ocrelizumab induce differential miRNA profiles in peripheral blood mononucleated cells from relapsing-remitting multiple sclerosis patients	FRONTIERS IN IMMUNOLOGY	2023
Disordered eating in early childhood: DRD4 and DAT1 gene polymorphisms and quality of mother–child interaction	EATING AND WEIGHT DISORDERS	2022
Methylation patterns within 5'-UTR of DAT1 gene as a function of allelic 3'-UTR variants and their maternal or paternal origin: may these affect the psychopathological phenotypes in children? An explorative study	NEUROSCIENCE LETTERS	2022
Genetics influences drug consumption in medication overuse headache, not in migraine. Evidence from Wolframin His611Arg polymorphism analysis	FRONTIERS IN NEUROLOGY	2021
Epigenetic regulation of DAT gene promoter modulates the risk of Externalizing and Internalizing behaviors on a normative population: an explorative study	BEHAVIOURAL BRAIN RESEARCH	2021
Interazione gene- ambiente e rischio psicopatologico in età scolare. Il ruolo del genotipo DAT1 del bambino e dell’ambiente affettivo familiare	PSICOLOGIA CLINICA DELLO SVILUPPO	2021
DNA methylation of the 5'-UTR DAT 1 gene in Parkinson's disease patients	ACTA NEUROLOGICA SCANDINAVICA	2020
DAT1 Gene methylation as an epigenetic biomarker in attention deficit hyperactivity disorder. A commentary	FRONTIERS IN GENETICS	2020
Cross-correlations between motifs in the 5′-UTR of DAT1 gene. Findings from Parkinson’s disease	ADVANCES IN BIOLOGICAL REGULATION	2020
Associations Among Internet Addiction, Genetic Polymorphisms, Family Functioning, and Psychopathological Risk: Cross-Sectional Exploratory Study	JMIR. JOURNAL OF MEDICAL INTERNET RESEARCH	2020
Search for an epigenetic biomarker in ADHD diagnosis, based on the DAT1 gene 5’-UTR methylation: a new possible approach	PSYCHIATRY RESEARCH	2020
Involvement of DAT1 gene on internet addiction: Cross-correlations of methylation levels in 5'-utr and 3’-UTR genotypes, interact with impulsivity and attachment-driven quality of relationships	INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH	2020
Beyond the dyad: the role of mother and father in newborns’ global DNA methylation during the first month of life—a pilot study	DEVELOPMENTAL PSYCHOBIOLOGY	2020
DAT gene polymorphisms (rs28363170, rs393795) and levodopa-induced dyskinesias in Parkinson's disease	NEUROSCIENCE LETTERS	2019
On the role of adenosine a2a receptor gene transcriptional regulation in parkinson’s disease	FRONTIERS IN NEUROSCIENCE	2019
Children’s DAT1 polymorphism moderates the relationship between parents’ psychological profiles, children’s DAT methylation, and their emotional/behavioral functioning in a normative sample	INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH	2019

ERC

LS1_3
LS2_1
LS2_3
LS5_8
LS5_11

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Studio di polimorfismi genici in alcune malattie neurodegenerative umane, in particolare nella malattia di Parkinson, come punto di partenza per comprendere i meccanismi molecolari alla base della malattia e per l’identificazione di nuovi target per lo sviluppo di terapie innovative.

Ruolo dei polimorfismi genici di selezionati neurotrasmettitori nella suscettibilità alle dipendenze da alcol, internet gaming e disordini alimentari.

Analisi del profilo di metilazione di selezionati neurotrasmettitori

Keywords

dopamine transporter (DAT

Alcohol addiction

Attention Deficit Disorder with Hyperactivity

gene polymorphis

genetics and molecular biolog

parkinson's diseas

Serotonin Transporte

single nucleotide polymorphis

Gruppi di ricerca

Genetica ed epigenetica della psicopatologia