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francesca.megiorni@uniroma1.it
Francesca Megiorni
Professore Associato
Struttura:
DIPARTIMENTO DI MEDICINA SPERIMENTALE
E-mail:
francesca.megiorni@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks
CELL DEATH DISCOVERY
2024
Antitumour effects of SFX-01 molecule in combination with ionizing radiation in preclinical and in vivo models of rhabdomyosarcoma
BMC CANCER
2024
Polyethylene micro/nanoplastics exposure induces epithelial-mesenchymal transition in human bronchial and alveolar epithelial cells
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024
Assessing the Impact of Polyethylene Nano/Microplastic Exposure on Human Vaginal Keratinocytes
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023
Targeting FGFRs by pemigatinib induces G1 phase cell cycle arrest, cellular stress and upregulation of tumor suppressor microRNAs
JOURNAL OF TRANSLATIONAL MEDICINE
2023
Sex-related factors in cardiovascular complications associated to COVID-19
BIOMOLECULES
2022
Anti‑oncogenic and pro‑myogenic action of the MKK6/p38/AKT axis induced by targeting MEK/ERK in embryonal rhabdomyosarcoma
ONCOLOGY REPORTS
2022
Radioresistance in rhabdomyosarcomas: much more than a question of dose
FRONTIERS IN ONCOLOGY
2022
Translational implications for radiosensitizing strategies in rhabdomyosarcoma
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo
FRONTIERS IN PHARMACOLOGY
2022
Inhibiting DNA methylation as a strategy to enhance adipose-derived stem cells differentiation. Focus on the role of Akt/mTOR and Wnt/β-catenin pathways on adipogenesis
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2022
Testosterone-to-estradiol ratio and platelet thromboxane release in ischemic heart disease: the EVA project
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
2022
Protein–protein interaction network analysis applied to DNA copy number profiling suggests new perspectives on the aetiology of Mayer–Rokitansky–Küster–Hauser syndrome
SCIENTIFIC REPORTS
2021
MiR-200c-3p contrasts PD-L1 induction by combinatorial therapies and slows proliferation of epithelial ovarian cancer through downregulation of β-Catenin and c-Myc
CELLS
2021
OTX015 epi‐drug exerts antitumor effects in ovarian cancer cells by blocking GNL3‐mediated radioresistance mechanisms: Cellular, molecular and computational evidence
CANCERS
2021
Altered expression of candidate genes in Mayer–Rokitansky–Küster–Hauser syndrome may influence vaginal keratinocytes biologya. A focus on Protein Kinase X
BIOLOGY
2021
Calcineurin gamma catalytic subunit ppp3cc inhibition by mir-200c-3p affects apoptosis in epithelial ovarian cancer
GENES
2021
MiR-200c-3p maintains stemness and proliferative potential in adipose-derived stem cells by counteracting senescence mechanisms
PLOS ONE
2021
Dnmt3a and dnmt3b targeting as an effective radiosensitizing strategy in embryonal rhabdomyosarcoma
CELLS
2021
MS−275 (Entinostat) promotes radio-sensitivity in PAX3-FOXO1 rhabdomyosarcoma cells
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
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Progetti di Ricerca
Epigenetic dynamics for enhancing therapeutic efficacy and immunomodulatory activity of adipose-derived stem cells in regenerative medicine: a biological, molecular and computational approach.
Non-coding RNAs and epigenetic drivers in ovarian cancer development and drug resistance: cues to new biomarkers and efficient targeted therapies.
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