Ilaria Grazia Zizzari

Pubblicazioni

Titolo Pubblicato in Anno
CD137+ and regulatory T cells as independent prognostic factors of survival in advanced non-oncogene addicted NSCLC patients treated with immunotherapy as first-line JOURNAL OF TRANSLATIONAL MEDICINE 2024
Precision oncology targeting FGFRs: A systematic review on pre-clinical activity and clinical outcomes of pemigatinib CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 2024
Immune-related toxicity and soluble profile in patients affected by solid tumors: a network approach CANCER IMMUNOLOGY, IMMUNOTHERAPY 2023
Circulating CD137+ T cell levels are correlated with response to pembrolizumab treatment in advanced head and neck cancer patients INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity JOURNAL OF IMMUNOLOGY RESEARCH 2023
Macrophage galactose-like lectin mediated interactions: investigating immunosuppressive mechanisms in glioblastoma www.siica.it 2023
A network approach to define the predictive role of immune profile on tumor response and toxicity of anti PD-1 single agent immunotherapy in patients with solid tumors FRONTIERS IN IMMUNOLOGY 2023
Targeting FGFRs by pemigatinib induces G1 phase cell cycle arrest, cellular stress and upregulation of tumor suppressor microRNAs JOURNAL OF TRANSLATIONAL MEDICINE 2023
Circulating CD137+ T cell subsets and MDCSs as immune biomarkers for response to anti-PD1 immunotherapy in NSCLC patients AICC INTERNATIONAL MEETING – TRANSLATIONAL AND PRECISION MEDICINE 2023
Circulating CD137 + T cells correlate with improved response to anti-PD1 immunotherapy in cancer patients CLINICAL CANCER RESEARCH 2022
Circulating immune profile can predict survival of metastatic uveal melanoma patients: results of an exploratory study HUMAN VACCINES & IMMUNOTHERAPEUTICS 2022
Immune effects of CDK4/6 inhibitors in patients with HR+/HER2− metastatic breast cancer: relief from immunosuppression is associated with clinical response EBIOMEDICINE 2022
Glycan-Lectin Interactions as Novel Immunosuppression Drivers in Glioblastoma INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential JOURNAL OF HEPATOLOGY 2022
Soluble PD-L1 as a prognostic factor for Immunotherapy treatment in solid tumors: Systematic review and Meta-Analysis INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Genomic and immune approach in platinum refractory HPV-negative head and neck squamous cell carcinoma patients treated with Immunotherapy: a novel combined profile BIOMEDICINES 2022
The role of immune profile in predicting outcomes in cancer patients treated with immunotherapy FRONTIERS IN IMMUNOLOGY 2022
The role of soluble LAG3 and soluble immune checkpoints profile in advanced head and neck cancer: a pilot study JOURNAL OF PERSONALIZED MEDICINE 2021
Anti–PD-1 and Anti–PD-L1 in head and neck cancer: a network meta-analysis FRONTIERS IN IMMUNOLOGY 2021
Immunogenic cell death and immunomodulatory effects of cabozantinib FRONTIERS IN ONCOLOGY 2021

ERC

  • LS6
  • LS6_2
  • LS6_3
  • LS6_11
  • LS7_2

Interessi di ricerca

Studio dei meccanismi di interazione tra tumore e cellule del sistema immunitario.

 

Analisi della fitness immunologica di pazienti con tumori solidi.

 

Vaccinazione anti-tumorale a base peptidica o mediante la somministrazione di cellule dendritiche (DC) autologhe pulsate con proteine ricombinanti o lisato tumorale.

 

Produzione di nuovi immunogeni per la terapia anti-tumore

 

Isolamento ex vivo di immunogeni per la vaccinazione anti-tumore.

 

Monitoraggio Immunologico nei trials clinici di Immunoterapia Sperimentale in Oncologia

Keywords

anticancer immunotherapy
anti-tumor immune response
biomarkers tumor
dendritic cells

Progetti di Ricerca

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