Daniela Secci

Pubblicazioni

Titolo Pubblicato in Anno
Suppression capacity and environmental impact of three extinguishing agents for lithium-ion battery fires CASE STUDIES IN CHEMICAL AND ENVIRONMENTAL ENGINEERING 2024
Chiral Hydroxy Metabolite of Mebendazole: Analytical and Semi-Preparative High-Performance Liquid Chromatography Resolution and Chiroptical Properties PHARMACEUTICALS 2024
Scalable microfluidic method for tunable liposomal production by a design of experiment approach INTERNATIONAL JOURNAL OF PHARMACEUTICS 2024
Inhibition of intestinal inflammation and fibrosis by Scutellaria Baicalensis georgi and Boswellia serrata in human epithelial cells and fibroblasts IMMUNITY, INFLAMMATION AND DISEASE 2024
Carbon Monoxide Release from Aryl-Propargyl Dicobalt(0)Hexacarbonyl Derivatives: A Computational and Experimental Study INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2024
Novel Insights on CAI–CORM Hybrids: Evaluation of the CO Releasing Properties and Pain-Relieving Activity of Differently Substituted Coumarins for the Treatment of Rheumatoid Arthritis JOURNAL OF MEDICINAL CHEMISTRY 2023
Indoleamine 2,3-dioxygenase Metalloenzymes: from bench to bedside 2023
Kinetic Study on the Base-Catalyzed Imine-Enamine Tautomerism of a Chiral Biologically Active Isoxazoline Derivative by HPLC on Amylose Tris(3,5-dimethylphenylcarbamate) Chiral Stationary Phase MOLECULES 2023
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration ANTIOXIDANTS 2023
Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Metal-organic frameworks (MOFs) as biomolecules drug delivery systems for anticancer purposes EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2022
Treatment of Toxoplasmosis: An Insight on Epigenetic Drugs Topics in Medicinal Chemistry 2022
A comparative study on the suppression capacity and the environmental impact of different extinguishing agents of lithium-ion battery fires Proceedings of the Tenth International Seminar on Fire and Explosion Hazards, 22-27 May 2022, Oslo, Norway 2022
Synthesis and Evaluation of Thymol-Based Synthetic Derivatives as Dual-Action Inhibitors against Different Strains of H. pylori and AGS Cell Line MOLECULES 2021
An innovative spectroscopic approach for qualitative and quantitative evaluation of Mb-CO from myoglobin carbonylation reaction through chemometrics methods SPECTROCHIMICA ACTA. PART A, MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 2021
High-performance liquid chromatography enantioseparation of chiral 2-(benzylsulfinyl)benzamide derivatives on cellulose tris(3,5-dichlorophenylcarbamate) chiral stationary phase JOURNAL OF CHROMATOGRAPHY A 2020
1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors JOURNAL OF MEDICINAL CHEMISTRY 2020
Metabolic profiling of different wild and cultivated Allium species based on high-resolution mass spectrometry, high-performance liquid chromatography-photodiode array detector, and color analysis JOURNAL OF MASS SPECTROMETRY 2020
Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 2020
Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2020

ERC

  • LS1_13
  • PE5_17
  • PE5_18

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

  1. Progettazione, sintesi e valutazione biologica di nuovi inibitori selettivi sulle mono ammino ossidasi, MAO-A e MAO-B,
  2. Progettazione, sintesi e valutazione biologica di nuovi modulatori epigenetici con particolare riferimento agli inibitori dell’acetiltransferasi (HATs) ad attività apoptotica e citodifferenziante
  3. Progettazione, sintesi e valutazione biologica di nuovi inibitori selettivi delle isoforme IX e XII dell’anidrasi carbonica per il trattamento di patologie tumorali
  4. Sviluppo e la caratterizzazione di anticorpi monoclonali biosimilari per uso terapeutico isolati da piante transgeniche
  5. Sviluppo e sintesi di metal-organic frameworks (MOFs) per applicazioni biomediche.

Keywords

drug design and discovery
Anticancer agents
neuroprotective agents
Anti-Infective Agents

Laboratori di ricerca

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma