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sergio.fucile@uniroma1.it
Sergio Fucile
Professore Ordinario
Struttura:
DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER"
E-mail:
sergio.fucile@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Selective Reduction of Ca2+ Entry Through the Human NMDA Receptor: a Quantitative Study by Simultaneous Ca2+ and Na+ Imaging
MOLECULAR NEUROBIOLOGY
2024
Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties
HELIYON
2024
Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase, modulates glycosphingolipid metabolism and results therapeutically effective in experimental models of Huntington's disease
MOLECULAR THERAPY
2023
Natural killer cells and innate lymphoid cells 1 tune anxiety-like behavior and memory in mice via interferon-γ and acetylcholine
NATURE COMMUNICATIONS
2023
α7 Nicotinic Acetylcholine Receptors May Improve Schwann Cell Regenerating Potential via Metabotropic Signaling Pathways
CELLS
2023
Common and Rare Variants in TMEM175 Gene Concur to the Pathogenesis of Parkinson's Disease in Italian Patients
MOLECULAR NEUROBIOLOGY
2023
Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase, modulates glycosphingolipid metabolism and results therapeutically effective in experimental models of Huntington's disease
MOLECULAR THERAPY
2023
Reduction of inflammation and mitochondrial degeneration in mutant SOD1 mice through inhibition of voltage-gated potassium channel Kv1.3
FRONTIERS IN MOLECULAR NEUROSCIENCE
2023
Contribution of CACNA1H Variants in Autism Spectrum Disorder Susceptibility
FRONTIERS IN PSYCHIATRY
2022
Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity
BIOMEDICINES
2022
A Progressive Build-up of Perineuronal Nets in the Somatosensory Cortex Is Associated with the Development of Chronic Pain in Mice
THE JOURNAL OF NEUROSCIENCE
2022
5-HT3 Receptors in Rat Dorsal Root Ganglion Neurons: Ca2+ Entry and Modulation of Neurotransmitter Release
LIFE
2022
ATP-evoked intracellular Ca2+ transients shape the ionic permeability of human microglia from epileptic temporal cortex
JOURNAL OF NEUROINFLAMMATION
2021
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9-nicotinic ligands on glioblastoma cells
PHARMACOLOGICAL RESEARCH
2021
New nutraceutical combination reduces blood pressure and improves exercise capacity in hypertensive patients via a nitric oxide-dependent mechanism
JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE
2020
Co-occurring WARS2 and CHRNA6 mutations in a child with a severe form of infantile parkinsonism
PARKINSONISM & RELATED DISORDERS
2020
Modulation of GABAergic dysfunction due to SCN1A mutation linked to Hippocampal Sclerosis
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
2020
The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia
SCHIZOPHRENIA BULLETIN
2020
Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype
JOURNAL OF MEDICINAL CHEMISTRY
2020
Chronic neural interfacing with cerebral cortex using single-walled carbon nanotube-polymer grids
JOURNAL OF NEURAL ENGINEERING
2020
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Progetti di Ricerca
Il controllo della concentrazione di Ca2+ libero intracellulare per la riduzione del danno cellulare da eccitotossicità
Positive allosteric modulation of human neuronal nicotinic acetylcholine receptors as a new strategy to enhance cortical GABAergic inhibitory neurotransmission and treat epilepsy
Laboratori di ricerca
Laboratorio di elettrofisiologia 2 — calcio (Dipartimento Fisiologia & Farmacologia – CU027)
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