Pubblicazioni

N6-methyladenosine (m6A) RNA modification in chronic myeloid leukemia: unveiling a novel therapeutic target

2024 - CELLULAR AND MOLECULAR LIFE SCIENCES

Fernandez Rodriguez, Guillermo; Tarullo, Marco; Fatica, Alessandro

Determinants of frontline tyrosine kinase inhibitor choice for patients with chronic-phase chronic myeloid leukemia: A study from the Registro Italiano LMC and Campus CML

2023 - CANCER

Tiribelli, Mario; Latagliata, Roberto; Breccia, Massimo; Capodanno, Isabella; Miggiano, Maria Cristina; Cavazzini, Francesco; Bucelli, Cristina; Attolico, Immacolata; Crescenzi, Sabrina Leonetti; Russo, Sabina; Annunziata, Mario; Sora, Federica; Bonifacio, Massimiliano; Mulas, Olga; Loglisci, Giuseppina; Maggi, Alessandro; Binotto, Gianni; Crisa, Elena; Scortechini, Anna Rita; Leporace, Anna Paola; Sancetta, Rosaria; Murgano, Pamela; Abruzzese, Elisabetta; Stagno, Fabio; Rapezzi, Davide; Luzi, Debora; Vincelli, Iolanda; Bocchia, Monica; Fava, Carmen; Malato, Alessandra; Crugnola, Monica; Pizzuti, Michele; Lunghi, Francesca; Galimberti, Sara; Dalmazzo, Matteo; Fanin, Renato; Scalzulli, Emilia; Foa, Robin; Iurlo, Alessandra; Saglio, Giuseppe; Specchia, Giorgina

Real-World Analysis of the Therapeutic Management and Disease Burden in Chronic Myeloid Leukemia Patients with Later Lines in Italy

2022 - JOURNAL OF CLINICAL MEDICINE

Breccia, Massimo; Chiodi, Francesca; Nardozza, Aurelio Pio; Valsecchi, Diletta; Perrone, Valentina; Sangiorgi, Diego; Giacomini, Elisa; Rendace, Maria Chiara; Coco, Paola; Premoli, Eleonora; Degli Esposti, Luca

Dihydroorotate Dehydrogenase Inhibition Reveals Metabolic Vulnerability in Chronic Myeloid Leukemia

2022 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Houshmand, Mohammad; Vitale, Nicoletta; Orso, Francesca; Cignetti, Alessandra; Molineris, Ivan; Gaidano, Valentina; Sainas, Stefano; Giorgis, Marta; Boschi, Donatella; Fava, Carmen; Iurlo, Alessandra; Abruzzese, Elisabetta; Breccia, Massimo; Mulas, Olga; Caocci, Giovanni; Castagnetti, Fausto; Taverna, Daniela; Pane, Fabrizio; Lolli, Marco; Circosta, Paola; Saglio, Giuseppe

Asciminib Provides Durable Molecular Responses in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With the T315I Mutation: Updated Efficacy and Safety Data From a Phase I Trial

2022 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Hughes, Timothy P.; Cortes, Jorge E.; Rea, Delphine; Mauro, Michael J.; Hochhaus, Andreas; Kim, Dong-Wook; Sasaki, Koji; Lang, Fabian; Heinrich, Michael C.; Breccia, Massimo; Deininger, Michael; Goh, Yeow-Tee; Janssen, ; Jeroen, J. W. M.; Talpaz, Moshe; le Coutre, Philipp; Kapoor, Shruti; Cacciatore, Silvia; Polydoros, Fotis; Agrawal, Nithya; Mahon, Francois-Xavier

CML-164 Dihydroorotate Dehydrogenase Inhibition Reveals Metabolic Vulnerability in Chronic Myeloid Leukemia

2022 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Houshmand, Mohammad; Vitale, Nicoletta; Orso, Francesca; Cignetti, Alessandro; Molineris, Ivan; Gaidano, Valentina; Sainas, Stefano; Giorgis, Marta; Boschi, Donatella; Fava, Carmen; Iurlo, Alessandra; Abruzzese, Elisabetta; Breccia, Massimo; Mulas, Olga; Caocci, Giovanni; Castagnetti, Fausto; Taverna, Daniela; Pane, Fabrizio; Lolli, Marco; Circosta, Paola; Saglio, Giuseppe

CML-466 Asciminib Provides Durable Molecular Responses in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With the T315I Mutation: Updated Efficacy and Safety Data From a Phase I Trial

2022 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Hughes, Timothy P.; Cortes, Jorge E.; RÃ©a, Delphine; Mauro, Michael J.; Hochhaus, Andreas; Kim, Dong-Wook; Sasaki, Koji; Lang, Fabian; Heinrich, Michael C.; Breccia, Massimo; Deininger, Michael; Goh, Yeow-Tee; Janssen, Jeroen J. W. M; Talpaz, Moshe; Coutre, Philipp le; Kapoor, Shruti; Cacciatore, Silvia; Polydoros, Fotis; Agrawal, Nithya; Mahon, Francois-Xavier

Digital droplet PCR as a predictive tool for successful discontinuation outcome in chronic myeloid leukemia: Is it time to introduce it in the clinical practice?

2021 - CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Colafigli, Gioia; Scalzulli, Emilia; Di Prima, Alessio; Pepe, Sara; Loglisci, Maria Giovanna; Diverio, Daniela; Martelli, Maurizio; FoÃ , Robin; Breccia, Massimo

Asciminib Provides Durable Responses and a Favorable Safety Profile in Patients with Chronic Myeloid Leukemia (CML) in Chronic Phase (CP) with the T315I Mutation in a Phase 1 Study

2021 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Cortes, Jorge E.; Hughes, Timothy P.; Mauro, Michael J.; Hochhaus, Andreas; Rea, Delphine; Goh, Yeow-Tee; Janssen, J. J. W. M.; Heinrich, Michael C.; Talpaz, Moshe; Etienne, Gabriel; Breccia, Massimo; Deininger, Michael; Le Coutre, Philipp; Lang, Fabian; Polydoros, Fotis; Cacciatore, Silvia; Stenson, Laura; Kim, Dong-Wook

Digital droplet PCR as a predictive tool for successful discontinuation outcome in chronic myeloid leukemia: Is it time to introduce it in the clinical practice?

2020 - CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Colafigli, G.; Scalzulli, E.; Di Prima, A.; Pepe, S.; Loglisci, M. G.; Diverio, D.; Martelli, M.; Foa, R.; Breccia, M.

Health-related quality of life of newly diagnosed chronic myeloid leukemia patients treated with first-line dasatinib versus imatinib therapy

2020 - LEUKEMIA

Efficace, Fabio; Stagno, Fabio; Iurlo, Alessandra; Breccia, Massimo; Cottone, Francesco; Bonifacio, Massimiliano; Abruzzese, Elisabetta; Castagnetti, Fausto; Caocci, Giovanni; Crugnola, Monica; Capodanno, Isabella; Martino, Bruno; Tiribelli, Mario; Patriarca, Andrea; Gozzini, Antonella; Pregno, Patrizia; Saussele, Susanne; Cascavilla, Nicola; Fozza, Claudio; Bergamaschi, Micaela; Binotto, Gianni; Vignetti, Marco; Rosti, Gianantonio

Relationship Between High Body Mass Index (BMI) and Treatment Outcomes in Patients with Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Treated with Dasatinib or Imatinib: Retrospective Analysis of the Phase 3 DASISION Trial

2020 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Breccia, Massimo; Cortes Jorge, E.; Shah Neil, P.; Saglio, Giuseppe; Jimenez-Velasco, Antonio; Le Coutre, Philipp; Brun, Alexander; Degutis, Irene; Bathena, Sai; Sy, Oumar; Jabbour, Elias

Efficacy and Safety of Asciminib in Heavily Pretreated Patients with Philadelphia Chromosome-Positive (Ph plus ) Chronic Myeloid Leukemia in Chronic Phase (CML-CP) with Sensitivity to Tyrosine Kinase Inhibitors (TKIs)

2020 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Hughes, Timothy; Mauro, Michael; Kim, Dong-Wook; Cortes, Jorge; Rea, Delphine; Minami, Hironobu; Breccia, Massimo; Deangelo, Daniel; Hochhaus, Andreas; Goh, Yeow-Tee; le Coutre, Philipp; Lang, Fabian; Cacciatore, Silvia; Aimone, Paola; Stenson, Laura; Polydoros, Fotis; Talpaz, Moshe

Atypical chronic myeloid leukemia in a patient with aplastic anemia

2019 - ACTA HAEMATOLOGICA

Santopietro, Michelina; Miano, Maurizio; Palumbo, Giovanna; Zhang, Kejian; Cardarelli, Luisa; Chiaretti, Sabina; Peragine, Nadia; Nanni, Mauro; Diverio, Daniela; Mancini, Francesca; Testi, Anna Maria; Moleti, Maria Luisa; FoÃ , Robin; Giona, Fiorina

Combination of Asciminib plus Nilotinib or Asciminib plus Dasatinib in Previously Treated Chronic Myeloid Leukemia (CML) Patients: Phase 1 Study Results

2019 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Deangelo, Daniel J.; Mauro, Michael J.; Kim, Dong-Wook; Cortes, Jorge; RÃ©a, Delphine; Hughes, Timothy P.; Minami, Hironobu; Breccia, Massimo; Talpaz, Moshe; Hochhaus, Andreas; Tee Goh, Yeow; Le Coutre, Philipp D.; Sondhi, Manu; Mishra, Kaushal; Hourcade-Potelleret, Florence; Vanasse, Gary; Aimone, Paola; Lang, Fabian

Efficacy and Safety of Asciminib, a Specific Allosteric BCR-ABL1 Inhibitor Targeting the Myristoyl-Binding Site, in Patients with Chronic Myeloid Leukemia (CML) Carrying the T315I Mutation

2019 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Deininger, Michael W.; RÃ©a, Delphine; Lang, Fabian; Kim, Dong-Wook; Cortes, Jorge E.; Hughes, Timothy P.; Minami, Hironobu; Breccia, Massimo; Deangelo, Daniel J.; Hochhaus, Andreas; Talpaz, Moshe; Tee Goh, Yeow; Le Coutre, Philipp D.; Etienne, Gabriel; Sondhi, Manu; Mishra, Kaushal; Aimone, Paola; Mauro, Michael J.

Combination of Asciminib, a Novel and Specific BCR-ABL1 Inhibitor, Plus Imatinib in Previously Treated Chronic Myeloid Leukemia (CML) Patients: Phase 1 Study Results

2019 - CLINICAL LYMPHOMA MYELOMA & LEUKEMIA

Talpaz, Moshe; Cortes, Jorge; Lang, Fabian; Kim, Dong-Wook; RÃ©a, Delphine; Mauro, Michael J.; Minami, Hironobu; Breccia, Massimo; Deangelo, Daniel J.; Hochhaus, Andreas; Tee Goh, Yeow; Le Coutre, Philipp D.; Sondhi, Manu; Mishra, Kaushal; Hourcade-Potelleret, Florence; Vanasse, Gary; Aimone, Paola; Hughes, Timothy P.

Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure

2019 - THE NEW ENGLAND JOURNAL OF MEDICINE

Hughes, T. P.; Mauro, M. J.; Cortes, J. E.; Minami, H.; Rea, D.; Deangelo, D. J.; Breccia, M.; Goh, Y. -T.; Talpaz, M.; Hochhaus, A.; le Coutre, P.; Ottmann, O.; Heinrich, M. C.; Steegmann, J. L.; Deininger, M. W. N.; Janssen, J. J. W. M.; Mahon, F. -X.; Minami, Y.; Yeung, D.; Ross, D. M.; Tallman, M. S.; Park, J. H.; Druker, B. J.; Hynds, D.; Duan, Y.; Meille, C.; Hourcade-Potelleret, F.; Vanasse, K. G.; Lang, F.; Kim, D. -W.

Early response does not predict outcome in children and adolescents with chronic myeloid leukaemia treated with high-dose imatinib

2018 - BRITISH JOURNAL OF HAEMATOLOGY

Giona, Fiorina; Saglio, Giuseppe; Santopietro, Michelina; Menna, Giuseppe; Putti, Maria Caterina; Micalizzi, Concetta; Iaria, Grazia; Santoro, Nicola; Ladogana, Saverio; Mura, Rosamaria; Burnelli, Roberta; Consarino, Caterina; Cosmi, Carlo; Moleti, Maria Luisa; Leszl, Anna; Tucci, Francesca; Nanni, Mauro; Diverio, Daniela; Biondi, Andrea; Locatelli, Franco; Foa, Roberto

Intermittent Imatinib mesylate in children with chronic myeloid leukemia: results and outcome

2018 - BLOOD

Malaspina, Francesco; Caterina Putti, Maria; Santopietro, Michelina; Ladogana, Saverio; Mura, Rosamaria; Burnelli, Roberta; Vacca, Nadia; Rizzo, Lorenzo; Moleti, MARIA LUISA; Testi, Anna Maria; Biondi, Andrea; Locatelli, Franco; Saglio, Giuseppe; Robin, FoÃ ; Giona, Fiorina

HLA-G molecules and clinical outcome in chronic myeloid leukemia

2017 - LEUKEMIA RESEARCH

Caocci, G; Greco, M; Arras, M; Cusano, R; Orru, S; Martino, B; Abruzzese, E; Galimberti, S; Mulas, O; Trucas, M; Littera, R; Lai, S; Carcassi, C; La Nasa, G.

Can chronic myeloid leukaemia in children and adolescents be successfully treated without haematopoietic stem cell transplant? A single centre experience

2016 - BRITISH JOURNAL OF HAEMATOLOGY

Giona, Fiorina; Moleti, Maria Luisa; De Benedittis, Daniela; Santopietro, Michelina; Nanni, Mauro; Testi, Anna Maria; Orlando, Sonia; Iori, Anna Paola; Piciocchi, Alfonso; Gottardi, Enrico; Barberi, Walter; Diverio, Daniela; Saglio, Giuseppe; Foa, Roberto

Management of Chronic Myeloid Leukemia in children and adolescents according to local guidelines the Italian experience

2016 - BLOOD

Giona, F; Santopietro, M; Menna, G; Putti, Mc; Micalizzi, C; Santoro, N; Ziino, O; Mura, R; Ladogana, S; Iaria, G; Sau, A; Burnelli, R; Vacca, N; Nardi, M; Consarino, C; Moleti, Ml; Nanni, M; Diverio, D; Leszl, A; Biondi, A; Locatelli, F; Saglio, G and FoÃ R