Pubblicazioni

Expanded Phase 1 Study of ABL001, a Potent, Allosteric Inhibitor of BCR-ABL, Reveals Significant and Durable Responses in Patients with CML-Chronic Phase with Failure of Prior TKI Therapy

2016 - BLOOD

Hughes, Tp; Goh, Yt; Ottmann, Og; Minami, H; Rea, D; Lang, F; Mauro, Mj; Deangelo, Dj; Talpaz, M; Hochhaus, A; Breccia, M; Cortes, Je; Heinrich, Mc; Janssen, J; Steegmann, Jl; Mahon, Fx; Duan, R; Iyer, V; Hynds, D; Vanasse, Gj; Kim, Dw

Obesity As a Risk Factor for Acute Promyelocytic Leukemia. Results from Population and Case-Control Studies Across Western Countries and Correlation with Gene Expression in the TCGA

2016 - BLOOD

Mazzarella, L; Botteri, E; Matthews, A; Disalvatore, D; Bagnardi, V; Breccia, M; Montesinos, P; Bernal, T; Gil, C; Ley, Tj; Sanz, Ma; Bhaskaran, K; Lo Coco, F; Pelicci, Pg

Predictors for Response to Ruxolitinib in Real-Life: An Observational Independent Study on 408 Patients with Myelofibrosis

2016 - BLOOD

Palandri, F; Palumbo, Ga; Bonifacio, M; Tiribelli, M; Benevolo, G; Martino, B; Abruzzese, E; D'Adda, M; Polverelli, N; Bergamaschi, M; Tieghi, A; Cavazzini, F; Ibatici, A; Crugnola, M; Bosi, C; Latagliata, R; Di Veroli, A; Scaffidi, L; De Marchi, F; Cerqui, E; Anaclerico, B; Di Raimondo, F; Vitolo, U; Lemoli, Rm; Fanin, R; Merli, F; Russo, D; Cuneo, A; Cavo, M; Vianelli, N; Breccia, M

The 'Next-in-Cml' Study: A Prospective Multicenter Study of Deep Sequencing of the BCR-ABL1 Kinase Domain in Philadelphia Chromosome-Positive Patients with Non-Optimal Responses to Tyrosine Kinase Inhibitor Therapy

2016 - BLOOD

Soverini, S; De Benedittis, C; Stella, S; Serra, A; Carnuccio, F; Errichiello, S; Bavaro, L; Castagnetti, F; Iurlo, A; Orofino, N; Sora, F; Sica, S; Galimberti, S; Barate, C; Mottadelli, F; Martelli, M; Novella, E; Di Bona, E; Specchia, G; Albano, F; Abruzzese, E; Ciceri, F; Lunghi, F; Fava, C; Cambrin, Gr; Luciano, L; Breccia, M; Caracciolo, C; Santoro, M; Di Raimondo, F; Gugliotta, G; Papayannidis, C; Cazzaniga, G; Mancini, M; Sancetta, R; Bassan, R; Musolino, C; Spinosa, G; Capalbo, Sf; Annunziata, M; Cavo, M; Rosti, G; Baccarani, M; Vigneri, P; Saglio, G; Pane, F; Martinelli, G

Prognostic Value of BCR-ABL1 Transcript Type in Chronic Myeloid Leukemia Patients Treated Frontline with Nilotinib

2016 - BLOOD

Castagnetti, F; Gugliotta, G; Breccia, M; Stagno, F; D'Adda, M; Levato, L; Carella, Am; Martino, B; Tiribelli, M; Fava, C; Binotto, G; Avanzini, P; Bocchia, M; Bergamaschi, M; Rossi, Ar; Cavazzini, F; Abruzzese, E; Soverini, S; Alimena, G; Cavo, M; Martinelli, G; Pane, F; Saglio, G; Baccarani, M; Rosti, G

Inclusion of Patient's Self-Reported Fatigue into a Standard Laboratory Risk Classification Enhances Survival Prediction in Patients with Advanced Myelodysplastic Syndromes

2016 - BLOOD

Efficace, F; Niscola, P; Cottone, F; Gaidano, G; Anota, A; Bonnetain, F; Caocci, G; Fianchi, L; Breccia, M; Stauder, R; Platzbecker, U; Palumbo, Ga; Luppi, M; Invernizzi, R; Bergamaschi, M; Fedele, M; Di Tucci, Aa; Zhang, Hy; Vignetti, M; Mandelli, F

Impact of Age on Efficacy, Safety, and Long-Term Outcome of Chronic Myeloid Leukemia (CML) Patients Treated in First-Line with Nilotinib: An Analysis of the Gimema CML Working Party

2016 - BLOOD

Gugliotta, G; Castagnetti, F; Breccia, M; D'Adda, M; Stagno, F; Levato, L; Carella, Am; Martino, B; Tiribelli, M; Cambrin, Gr; Gozzini, A; Salvucci, M; Cedrone, M; Trabacchi, E; Usala, E; Scortechini, Ar; Luciano, L; Soverini, S; Alimena, G; Cavo, M; Martinelli, G; Pane, F; Saglio, G; Baccarani, M; Rosti, G

Potentiation of Anti-Myeloma Activity of Daratumumab with Combination of Cyclophosphamide, Lenalidomide or Bortezomib Via a Tumor Secretory Response That Greatly Augments Macrophage-Induced ADCP

2016 - BLOOD

Rigalou, A; Ryan, A; Natoni, A; Chiu, C; Sasser, K; O'Dwyer, Me

A 13-Glycosylation Gene Signature in Multiple Myeloma Can Predicts Survival and Identifies Candidates for Targeted Therapy (GiMM13)

2016 - BLOOD

Connolly, C; Jha, A; Natoni, A; O'Dwyer, Me

Neonatal bone marrow transplantation prevents bone pathology in a mouse model of mucopolysaccharidosis type I

2015 - BLOOD

A., Pievani; I., Azario; L., Antolini; T., Shimada; P., Patel; Remoli, Cristina; B., Rambaldi; Valsecchi, M. G.; Riminucci, Mara; A., Biondi; S., Tomatsu; M., Serafini

Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders

2015 - BLOOD

A., Balakumaran; Mishra, P. J.; E., Pawelczyk; S., Yoshizawa; Bj, Swoder; N., Cherman; Sa, Kuznetsov; Bianco, Paolo; N., Giri; Sa, Savage; G., Merlino; B., Dumitriu; Dunbar, C. E.; Ns, Young; Alter, B. P.; Pg, Robey

Targeting the leukemia cell metabolism by the CPT1a inhibition. functional pre-clinical effects in leukemias

2015 - BLOOD

Ricciardi, Maria Rosaria; Mirabilii, Simone; Allegretti, Matteo; Licchetta, Roberto; Calarco, A; Torrisi, Maria Rosaria; Foa, Roberto; Nicolai, R; Peluso, G; Tafuri, Agostino

Utility of baseline 18FDG-PET/CT functional parameters in defining prognosis of primary mediastinal (thymic) large B-cell lymphoma

2015 - BLOOD

Ceriani, Luca; Martelli, Maurizio; Zinzani, Pier Luigi; Ferreri, AndrÃ©s J. M.; Botto, Barbara; Stelitano, Caterina; Gotti, Manuel; Cabras, Maria Giuseppina; Rigacci, Luigi; Gargantini, Livio; Merli, Francesco; Pinotti, Graziella; Mannina, Donato; Luminari, Stefano; Stathis, Anastasios; Russo, Eleonora; Cavalli, Franco; Giovanella, Luca; Johnson, Peter W. M.; Zucca, Emanuele

Are ET and PV Patients Two Similar Populations As Concern Thrombotic Risk Factors?

2015 - BLOOD

Andriani, A; Latagliata, R; Cedrone, M; Di Veroli, A; Santoro, Cristina; Spirito, F; Ruscio, C; Crescenzi Leonetti, S; Porrini, R; Di Giandomenico, J; Villiva, N; Spadea, A; Rago, A; De Gregoris, C; Cercola, P; Anaclerico, B; De Muro, M; Felici, S; Breccia, M; Montefusco, E; Bagnato, A; Cimino, Giuseppe; Majolino, I; Mazzucconi, Maria Gabriella; Alimena, C; Montanaro, M.

Application of the International Prognostic Score of Thrombosis for Essential Thrombocytemia(ET) (IPSET-Thrombosis) in a Cohort of ET Patients: Experience from Gruppo Laziale for Myeloproliferative Ph Negative Neoplasms

2015 - BLOOD

Cedrone, M; Anaclerico, B; Paoloni, F; Latagliata, R; Montanaro, M; Spirito, F; Crescenzi, Sl; Spadea, A; Porrini, R; Rago, A; Breccia, M; De Gregoris, C; Cimino, Giuseppe; Montefusco, E; Tafuri, A; Avvisati, G; Majolino, I; Lo Coco, F; Santoro, Cristina; Mazzucconi, Maria Gabriella; Ruscio, C; De Muro, M; Alimena, G; Andriani, A; Bagnato, A; Annino, L.

Health-Related Quality of Life in Patients with Primary Immune Thrombocytopenia (pITP): Investigating Differences Amongst Newly Diagnosed, Persistent and Chronic Pitp Patients

2015 - BLOOD

Efficace, Fabio; Fazi, P; Santoro, Cristina; Gaidano, G; Cottone, F; Borchiellini, A; Carpenedo, M; Simula, Mp; Di Giacomo, V; Pierri, I; Nobile, F; Rodeghiero, F; Scaramucci, L; Rambaldi, A; Cascavilla, N; Forghieri, F; Petrungaro, A; Ditonno, P; La Nasa, G; Cirrincione, S; Mandelli, Franco; Mazzucconi, Maria Gabriella

Clinical and Biological Features in Patients with Ph-Negative Chronic Myeloproliferative Neoplasm Showing Different Molecular Pattern. Comparative Study in 596 Patients of the Registro Italiano Trombocitemie (RIT)

2015 - BLOOD

Gugliotta, L; Iurlo, A; Gugliotta, G; Tieghi, A; Specchia, G; Gaidano, G; Candoni, A; Randi, Ml; Scalzulli, Pr; Dragani, A; Martinelli, V; Tagariello, G; Antonioli, E; Liberati, Am; Palmieri, R; Langella, M; Rago, A; Cacciola, Rr; Pierri, I; Ricco, A; Cattaneo, D; Santoro, U; Rupoli, S; Santoro, Cristina; Mastrullo, L; Martino, B; Mazzucconi, Maria Gabriella; Vianelli, N; De Stefano, V; Passamonti, F; Vannucchi, Am

The Platelet COUNT at Diagnosis of Essential Thrombocythemia Is a Prognostic Factor for Thrombosis-Free Survival: Retrospective Analysis on 1201 Patients

2015 - BLOOD

Montanaro, M; Latagliata, R; Cedrone, M; Di Veroli, A; Santoro, Cristina; Spirito, F; Ruscio, C; Leonetti Crescenzi, S; Porrini, R; Di Giandomenico, J; Villiva, N; Spadea, A; Rago, A; De Gregoris, C; Cercola, P; Anaclerico, B; De Muro, M; Felici, S; Breccia, M; Montefusco, E; Bagnato, A; Cimino, Giuseppe; Majolino, I; Mazzucconi, Maria Gabriella; Alimena, C; Andriani, A.

Early Response Does Not Impact on the Long-Term Outcome of Children and Adolescents with Chronic Myeloid Leukemia Treated with High-Dose Imatinib. The Italian Experience.

2015 - BLOOD

Giona, F; Saglio, G; Santopietro, M; Menna, G; Iaria, G; Putti, Mc; Micalizzi, C; Santoro, N; Ladogana, S; Mura, Rosamaria; Burnelli, R; Consarino, C; Cosmi, C; Moleti, Ml; Varotto, S; Tucci, F; Nanni, M; Diverio, D; Biondi, A; Locatelli, F; FoÃ , R.

Î³Î´ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-Î±Î²+/CD19+ lymphocytes

2015 - BLOOD

Airoldi, I.; Bertaina, A.; Prigione, I.; Zorzoli, A.; Pagliara, D.; Cocco, C.; Meazza, R.; Loiacono, F.; Lucarelli, B.; Bernardo, M. E.; Barbarito, G.; Pende, D.; Moretta, A.; Pistoia, V.; Moretta, L.; Locatelli, F.

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study

2015 - BLOOD

Inaba, H.; Zhou, Y.; Abla, O.; Adachi, S.; Auvrignon, A.; Beverloo, H. B.; De Bont, E.; Chang, T. -T.; Creutzig, U.; Dworzak, M.; Elitzur, S.; Fynn, A.; Forestier, E.; Hasle, H.; Liang, D. -C.; Lee, V.; Locatelli, F.; Masetti, R.; De Moerloose, B.; Reinhardt, D.; Rodriguez, L.; Van Roy, N.; Shen, S.; Taga, T.; Tomizawa, D.; Yeoh, A. E. J.; Zimmermann, M.; Raimondi, S. C.

Molecular prediction of durable remission after first-line fludarabinecyclophosphamide-rituximab in chronic lymphocytic leukemia

2015 - BLOOD

Rossi, Davide; Terzi Di Bergamo, Lodovico; De Paoli, Lorenzo; Cerri, Michaela; Ghilardi, Guido; Chiarenza, Annalisa; Bulian, Pietro; Visco, Carlo; Mauro, Francesca Romana; Morabito, Fortunato; Cortelezzi, Agostino; Zaja, Francesco; Forconi, Francesco; Laurenti, Luca; DEL GIUDICE, Ilaria; Gentile, Massimo; Vincelli, Iolanda; Motta, Marina; Coscia, Marta; Rigolin, Gian Matteo; Tedeschi, Alessandra; Neri, Antonino; Marasca, Roberto; Perbellini, Omar; Moreno, Carol; Del Poeta, Giovanni; Massaia, Massimo; Zinzani, Pier Luigi; Montillo, Marco; Cuneo, Antonio; Gattei, Valter; Foa, Roberto; Gaidano, Gianluca

Allogeneic cell transplant expands bone marrow distribution by colonizing previously abandoned areas: An FDG PET/CT analysis

2015 - BLOOD

Fiz, Francesco; Marini, Cecilia; Campi, Cristina; Massone, Anna Maria; PodestÃ , Marina; Bottoni, Gianluca; Piva, Roberta; Bongioanni, Francesca; Bacigalupo, Andrea; Piana, Michele; Sambuceti, Gianmario; Frassoni, Francesco

Different Levels of Alkaline Phospatase (ALP) in Multiple Myeloma (MM) and SOLID Tumors with BONE Lesions

2015 - BLOOD

Annibali, Ombretta; Petrucci, Maria Teresa; Santini, Daniele; Lisi, Elisabetta; Mariani, Marco; Pisani, Francesco; Bongarzoni, Velia; Venditti, Olga; Rago, Angela; Cerchiara, Elisabetta; Fiorini, Alessia; Franceschini, Luca; Felici, Stefano; Russano, Marco; Pantano, Francesco; Avvisati, Giuseppe

Very Elderly Patients with Chronic Phase-Chronic Myeloid Leukemia on Imatinib: No Impact of Concomitant Drugs on Complete Cytogenetic Response

2015 - BLOOD

Iurlo, A; Latagliata, R; Bucelli, C; Ferrero, D; Castagnetti, F; Breccia, M; Abruzzese, E; Cattaneo, D; Fava, C; Gozzini, A; Annunziata, M; Tiribelli, M; Pregno, P; Stagno, F; Vigneri, P; Cavazzini, F; Binotto, G; Mansueto, G; Russo, S; Falzetti, F; Montefusco, E; Gugliotta, G; Gasbarrino, C; D'Addosio, A; Cortesi, L; Cedrone, M; Rossi, Ar; Avanzini, P; Endri, M; Spadea, A; Celesti, F; Giglio, G; Isidori, A; Crugnola, M; Calistri, E; Sora, F; Rege-Cambrin, G; Sica, S; Luciano, L; Orlandi, Em; Bocchia, M; Tettamanti, M; Alimena, G; Saglio, G; Rosti, G; Nobili, A; Mannucci, Pm; Cortelezzi, A