Maria Rosaria Ricciardi

Pubblicazioni

Titolo Pubblicato in Anno
Low Cell Bioenergetic Metabolism Characterizes Chronic Lymphocytic Leukemia Patients with Unfavorable Genetic Factors and with a Better Response to BTK Inhibition CURRENT ISSUES IN MOLECULAR BIOLOGY 2024
YY1 knockdown relieves the differentiation block and restores apoptosis in AML cells CANCERS 2023
Doxorubicin-Induced Cardiac Senescence Is Alleviated Following Treatment with Combined Polyphenols and Micronutrients through Enhancement in Mitophagy CELLS 2023
Sirt5 inhibition induces brown fat-like phenotype in 3t3-l1 preadipocytes CELLS 2021
Corrigendum: Metabolic Reprogramming Promotes Myogenesis During Aging (Front. Physiol., (2019), 10, (897), 10.3389/fphys.2019.00897) FRONTIERS IN PHYSIOLOGY 2021
Bone marrow stromal cell-derived IL-8 upregulates PVR expression on multiple myeloma cells via NF-kB transcription factor CANCERS 2020
mTOR regulation of metabolism in hematologic malignancies CELLS 2020
Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma BLOOD ADVANCES 2020
The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in multiple myeloma. modulation by bromodomain and Extra-Terminal (BET) protein inhibitors CELL DEATH & DISEASE 2019
A rare BCR-ABL1 transcript in Philadelphia-positive acute myeloid leukemia. case report and literature review BMC CANCER 2019
Activation of liver X receptor up-regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms THE FASEB JOURNAL 2019
Central nervous system immune reconstitution inflammatory syndrome after autologous stem cell transplantation BONE MARROW TRANSPLANTATION 2019
Metabolic reprogramming promotes myogenesis during aging FRONTIERS IN PHYSIOLOGY 2019
Drug-induced senescent Multiple Myeloma cells elicit NK cell proliferation by direct or exosome-mediated IL-15 trans-presentation CANCER IMMUNOLOGY RESEARCH 2018
MICA-129 dimorphism and soluble MICA are associated with the progression of multiple myeloma FRONTIERS IN IMMUNOLOGY 2018
Differential proteomic profile of leukemic CD34+ progenitor cells from chronic myeloid leukemia patients ONCOTARGET 2018
Biological aspects of mTOR in leukemia INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018
Key role of the CD56lowCD16low Natural Killer cell subset in the recognition and killing of Multiple Myeloma cells CANCERS 2018
p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells ONCOIMMUNOLOGY 2017
Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: role of HSP70/TLR2/NF-kB axis ONCOIMMUNOLOGY 2017

ERC

  • LS1_9
  • LS2_15
  • LS3_1
  • LS3_5
  • LS4_11

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Attività di ricerca clinica traslazionale in patologie ematologiche con lo scopo di stabilire correlazioni prognostiche tra parametri biologici e clinico-diagnostici.

Tra i temi principali della mia attività di ricerca vi è lo studio 1) dei pathway molecolari proliferativi e anti-apoptotici, 2) del profilo di espressione proteica/fosfoproteica e 3) del profilo metabolico di cellule primarie di pazienti leucemici allo scopo di identificare profili peculiari di specifiche alterazioni genomiche e/o proteomiche e di selezionare bersagli molecolari di innovative terapie mirate.

Keywords

Acute leukemia
molecular targeted therapies
metabolic profile
phosphoproteomics
drug resistance

Progetti di Ricerca

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