Agostino Tafuri | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Prednisone vs high-dose dexamethasone in newly diagnosed adult primary immune thrombocytopenia: a randomised trial	BLOOD ADVANCES	2024
Venetoclax and Cobimetinib in Relapsed/Refractory AML: A Phase 1b Trial	CLINICAL LYMPHOMA MYELOMA & LEUKEMIA	2024
Low Cell Bioenergetic Metabolism Characterizes Chronic Lymphocytic Leukemia Patients with Unfavorable Genetic Factors and with a Better Response to BTK Inhibition	CURRENT ISSUES IN MOLECULAR BIOLOGY	2024
BASELINE QUALITY OF LIFE DATA MAY PREDICT ACHIEVEMENT OF EMR IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA TREATED WITH TKIS: RESULTS FROM THE GIMEMA-SUSTRENIM TRIAL	HEMASPHERE	2024
HYPEREOSINOPHILIC DISORDERS: PRELIMINARY REAL-WORLD ANALYSIS BY PH-NEGATIVE MPN LATIAL GROUP	HEMASPHERE	2024
Efficacy of Residual Site Radiation Therapy (ISRT) in Patients with Primary Mediastinal Lymphoma with Deauville Score 4 Following R-CHT: Results of a Retrospective Mono Institutional Study	JOURNAL OF CLINICAL MEDICINE	2023
Effects of ABVD chemotherapy on ovarian function: epidemiology, hormonal dosages and ultrasound morphologic analyses in 270 patients with Hodgkin's disease	FRONTIERS IN ONCOLOGY	2023
YY1 knockdown relieves the differentiation block and restores apoptosis in AML cells	CANCERS	2023
Doxorubicin-Induced Cardiac Senescence Is Alleviated Following Treatment with Combined Polyphenols and Micronutrients through Enhancement in Mitophagy	CELLS	2023
Correspondence in reference to the previously published manuscript: Reduction of cycles of bendamustine plus rituximab therapy in the cases with good response for indolent B-cell lymphomas	HEMATOLOGICAL ONCOLOGY	2023
The elderly prognostic index predicts early mortality in older patients with diffuse large B-cell lymphoma. An ad hoc analysis of the elderly project by the Fondazione Italiana Linfomi	HEMATOLOGICAL ONCOLOGY	2023
Venetoclax and idasanutlin in relapsed/refractory AML: a nonrandomized, open-label phase 1b trial	BLOOD	2023
The application of a multidisciplinary approach in the diagnosis of Castleman disease and Castleman-like lymphadenopathies: A 20-year retrospective analysis of clinical and pathological features	BRITISH JOURNAL OF HAEMATOLOGY	2023
Clinical impact of TP53 disruption in chronic lymphocytic leukemia patients treated with ibrutinib: a campus CLL study	LEUKEMIA	2023
Treatment discontinuation following low-dose TKIs in 248 chronic myeloid leukemia patients: Updated results from a campus CML real-life study	FRONTIERS IN PHARMACOLOGY	2023
Diffuse large B-cell lymphoma in octogenarians aged 85 and older can benefit from treatment with curative intent: a report on 129 patients prospectively registered in the Elderly Project of the Fondazione Italiana Linfomi (FIL)	HAEMATOLOGICA	2023
XPO1 mutations identify early-stage CLL characterized by shorter time to first treatment and enhanced BCR signalling	BRITISH JOURNAL OF HAEMATOLOGY	2023
Correction: Bocci et al. Remarkable Remission Rate and Long-Term Efficacy of Upfront Metronomic Chemotherapy in Elderly and Frail Patients, with Diffuse Large B-Cell Lymphoma. J. Clin. Med. 2022, 11, 7162	JOURNAL OF CLINICAL MEDICINE	2023
Successful Treatment of a Patient With Breast Implant-Associated Anaplastic Large Cell Lymphoma With Local Residual Disease. A Case Report	ANNALS OF PLASTIC SURGERY	2022
Daratumumab combined with dexamethasone and lenalidomide or bortezomib in relapsed/refractory multiple myeloma (RRMM) patients: report from the Multiple Myeloma Gimema Lazio Group	EUROPEAN JOURNAL OF HAEMATOLOGY	2022

ERC

LS1_9
LS2_15
LS3_1
LS3_5
LS4_11

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Studio dei meccanismi di resistenza della cellula leucemica ed identificazione del ruolo patogenetico e prognostico di profili aberranti proteomici e metabolomici implicati nei meccanismi proliferativi ed apoptotici. Sviluppo preclinico di molecole sperimentali con potenziale ruolo terapeutico target-specifico nelle onco-emopatie. Studio dei profili proteomici e metabolomici in cellule staminali emopoietiche umane normali e nella controparte leucemica.

Keywords

Acute leukemia

molecular targeted therapies

drug resistance

cell signaling

cell metabolism

Progetti di Ricerca

Laboratori di ricerca

laboratorio di cinetica cellulare, signaling e metabolismo in ematologia