Pubblicazioni

Adjuvant vemurafenib in resected, BRAF V600 mutation-positive melanoma (BRIM8): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial

2018 - THE LANCET ONCOLOGY

Maio, M.; Lewis, K.; Demidov, L.; Mandala, M.; Bondarenko, I.; Ascierto, P. A.; Herbert, C.; Mackiewicz, A.; Rutkowski, P.; Guminski, A.; Goodman, G. R.; Simmons, B.; Ye, C.; Yan, Y.; Schadendorf, D.; Cinat, G.; Fein, L. E.; Brown, M.; Guminski, A.; Haydon, A.; Khattak, A.; McNeil, C.; Parente, P.; Power, J.; Roberts-Thomson, R.; Sandhu, S.; Underhill, C.; Varma, S.; Berger, T.; Awada, A.; Blockx, N.; Buyse, V.; Mebis, J.; Franke, F. A.; Jobim de Azevedo, S.; Silva Lazaretti, N.; Jamal, R.; Mihalcioiu, C.; Petrella, T.; Savage, K.; Song, X.; Wong, R.; Dabelic, N.; Plestina, S.; Vojnovic, Z.; Arenberger, P.; Kocak, I.; Krajsova, I.; Kubala, E.; Melichar, B.; Vantuchova, Y.; Putnik, K.; Dreno, B.; Dutriaux, C.; Grob, J. -J.; Joly, P.; Lacour, J. -P.; Meyer, N.; Mortier, L.; Thomas, L.; Fluck, M.; Gambichler, T.; Hassel, J.; Hauschild, A.; Schadendorf, D.; Donnellan, P.; McCaffrey, J.; Power, D.; Ariad, S.; Bar-Sela, G.; Hendler, D.; Ron, I.; Schachter, J.; Ascierto, P.; Berruti, A.; Bianchi, L.; Chiarion Sileni, V.; Cognetti, F.; Danielli, R.; Di Giacomo, A. M.; Gianni, L.; Goldhirsch, A.; Guida, M.; Maio, M.; Mandala, M.; Marchetti, P.; Queirolo, P.; Santoro, A.; Kapiteijn, E.; Mackiewicz, A.; Rutkowski, P.; Ferreira, P.; Demidov, L.; Gafton, G.; Makarova, Y.; Andric, Z.; Babovic, N.; Jovanovic, D.; Kandolf Sekulovic, L.; Cohen, G.; Dreosti, L.; Vorobiof, D.; Curiel Garcia, M. T.; Diaz Beveridge, R.; Majem Tarruella, M.; Marquez Rodas, I.; Puliats Rodriguez, J. -M.; Rueda Dominguez, A.; Maroti, M.; Papworth, K.; Michielin, O.; Bondarenko, I.; Brown, E.; Corrie, P.; Harries, M.; Herbert, C.; Kumar, S.; Martin-Clavijo, A.; Middleton, M.; Patel, P.; Talbot, T.; Agarwala, S.; Chapman, P.; Conry, R.; Doolittle, G.; Gangadhar, T.; Hallmeyer, S.; Hamid, O.; Hernandez-Aya, L.; Johnson, D.; Kass, F.; Kolevska, T.; Lewis, K.; Lunin, S.; Salama, A.; Sikic, B.; Somer, B.; Spigel, D.; Whitman, E.

Tailoring adjuvant treatment in patients with uterine cancer

2018 - THE LANCET ONCOLOGY

Bogani, G; Chiappa, V; Lorusso, D; Raspagliesi, F.

Another treatment option for relapsed or refractory chronic lymphocytic leukaemia.

2017 - THE LANCET ONCOLOGY

Mauro, Francesca Romana

Rituximab-dose-dense chemotherapy with or without high-dose chemotherapy plus autologous stem-cell transplantation in high-risk diffuse large B-cell lymphoma (DLCL04): Final results of a multicentre, open-label, randomised, controlled, phase 3 study

2017 - THE LANCET ONCOLOGY

Chiappella, Annalisa; Martelli, Maurizio; Angelucci, Emanuele; Brusamolino, Ercole; Evangelista, Andrea; Carella, Angelo Michele; Stelitano, Caterina; Rossi, Giuseppe; Balzarotti, Monica; Merli, Francesco; Gaidano, Gianluca; Pavone, Vincenzo; Rigacci, Luigi; Zaja, Francesco; D'Arco, Alfonso; Cascavilla, Nicola; Russo, Eleonora; Castellino, Alessia; Gotti, Manuel; Congiu, Angela Giovanna; Cabras, Maria Giuseppina; Tucci, Alessandra; Agostinelli, Claudio; Ciccone, Giovannino; Pileri, Stefano A; Vitolo, Umberto

Rituximab and autologous stem-cell transplantation for high-risk diffuse large B-cell lymphoma - Authors' reply

2017 - THE LANCET ONCOLOGY

Chiappella, Annalisa; Martelli, Maurizio; Evangelista, Andrea; Vitolo, Umberto

Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET). 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial

2017 - THE LANCET ONCOLOGY

Martin, M.; Holmes, F. A.; Ejlertsen, B.; Delaloge, S.; Moy, B.; Iwata, H.; von Minckwitz, G.; Chia, S. K. L.; Mansi, J.; Barrios, C. H.; Gnant, M.; Tomasevic, Z.; Denduluri, N.; Separovic, R.; Gokmen, E.; Bashford, A.; Ruiz Borrego, M.; Kim, S. -B.; Jakobsen, E. H.; Ciceniene, A.; Inoue, K.; Overkamp, F.; Heijns, J. B.; Armstrong, A. C.; Link, J. S.; Joy, A. A.; Bryce, R.; Wong, A.; Moran, S.; Yao, B.; Xu, F.; Auerbach, A.; Buyse, M.; Chan, A.; Harvey, V.; Tomek, R.; Robert, N. J.; Gore, I.; Smith, J. W.; Masuda, N.; Di Sean Kendall, S.; Harker, W. G.; Petrakova, K.; Guerrero Zotano, A.; Simon, A. R.; Konstantinovic, Z. N.; Iannotti, N. O.; Tassone, P.; Rodriguez, G. I.; Janez Martinez, N.; Crespo Massieu, C.; Smickoska, S.; Somali, I.; Yilmaz, U.; Alonso, M. G.; Rosales, A. M.; Cold, S.; Knoop, A. S.; Patt, D.; Hellerstedt, B. A.; Morales Murillo, S.; Mayer, I. A.; Means-Powell, J. A.; Hui, R.; Senecal, F. M.; De Boer, R. H.; Shen, Z.; Luczak, A. A.; Chui, J. W. Y.; Tsang, J. W. -H.; Lang, I.; Rai, Y.; Hozumi, Y.; Ten Tije, A. J.; Bhandari, M.; Osborne, C. R. C.; Ohtani, S.; Higaki, K.; Watanabe, K.; Taguchi, K.; Takahashi, M.; Filipovic, S.; Hansen, V. L.; Rao, V. P.; Gupta, M.; Petrov, P.; Coudert, B.; Vojnovic, Z.; Polya, Z.; Miyaki, T.; Yamamoto, N.; Brincat, S.; Lesniewski-Kmak, K.; Chmielowska, E.; Birhiray, R. E.; Citron, M. L.; Papish, S. W.; Berry, W. R.; Langkjer, S. T.; Garcia Saenz, J. A.; Arance, A. M.; Efrat, N.; Sarosiek, T.; Grzeda, L.; Manalo, Y.; Smith, J. C.; Vaziri, I.; Healey, T.; Rahim, Y.; Luk, C.; Dingle, B.; Franco, S.; Sorensen, P. G.; Anand, A.; Khan, S.; Fountzilas, G.; Aogi, K.; Shimizu, S.; Mikulova, M.; Spanik, S.; Somer, R. A.; Flynn, P. J.; Coward, J.; Mainwaring, P.; Jerusalem, G.; Segura-Ojezzar, C.; Levy, C.; Delozier, T.; Khayat, D.; Coleman, R. E.; Rolles, M. J.; Maisano, R.; Nardi, M.; Ito, Y.; Yumuk, P. F.; Basaran, G.; Serdar Turhal, N.; Wilkinson, M. J.; Green, N. B.; Sidrys, A. P.; Hallmeyer, S.; Testori, D. J.; Sridhar, S.; Chang, J.; Sun, Q.; Jara-Sanchez, C.; Rubio, X.; Garrido, M. L.; De La Haba Rodriguez, J. R.; Perello Martorell, A.; Avelia Mestre, A.; Rifa Ferrer, J.; del Barco Berron, S.; Nagy, Z.; Tanaka, M.; Y. -H., Im; Carroll, R. R.; Dickerson, L. C.; Mace, J. R.; Rivera, R.; Klein, L. M.; Ruxer, R.; Wilks, S. T.; Kotasek, D.; Popov, V.; Taskova, V.; Marinova-Venkova, V.; Timcheva, C.; Desbiens, C.; Ayoub, J. -P.; Grenier, D.; Marschner, N.; Tesch, H.; Lueck, H. -J.; Janssen, J.; Schwaner, I.; Wahlstrom, S.; Brix, E. H.; Vallentin, S.; Kristensen, D.; Andreeva, A.; Glavicic, V.; Calvo Plaza, I.; Anton Torres, A.; Veyret, C.; Bergerat, J. -P.; Bourbouloux, E.; Ella, W. A.; Algurafi, H.; Robinson, A.; Kim, S. J.; Taguchi, T.; Juozaityte, E.; Madretsma, S.; Radema, S.; Czerniawska-Meier, M.; Rogowski, W.; Wagnerova, M.; Richards, D. A.; Tan-Chiu, E.; Vasileios, A.; Henderson, C. A.; Holden, V. R.; Wang, X.; Tong, Z.; Yang, J.; Gonzalez, M. E.; Rezai, M.; Hackmann, J.; de Duenas, E. M.; de las Heras, B. B.; Dourthe, L. M.; Chocteau-Bouju, D.; Bougnoux, P.; Kakolyris, S.; Kalofonos, H.; Pectasidis, D.; T. Y., Ng; Pajkos, G.; Somogyine, E. E.; Tonini, G.; Giuffrida, D.; Takao, S.; Ishitobi, M.; Inaji, H.; Tokuda, Y.; Wozniak, K.; Lungulescu, D.; Y. -S., Lu; Chang, K. -J.; Hill, J.; Croot, C. C.; Dekker, A.; Belman, N. D.; Conde, M.; Michaelson, R. A.; Kemmer, K.; Chui, S.; Luoh, S. -W.; Nahum, K.; Greenspan, A. R.; Nichols, J. C.; Encarnacion, C. A.; Niederman, T. M. J.; Lee, T.; Alexander, R.; Gordon, R.; Tomova, A.; Rauch, D.; Popescu, R. A.; Rojas, G. A.; Vanasek, J.; Neunhoeffer, T.; Barinoff, J.; Graffunder, G.; Wolfgang, A.; Bojko, P.; Heinrich, B.; von der Assen, A.; Antonovic, B. J.; Adrian, L.; Ramos Vazquez, M.; Gonzalez Santiago, S.; Dieras, V.; Bishop, J. M.; Perren, T. J.; Varthalitis, I.; Mavroudis, D.; Georgoulias, V.; Chow, L. W. C.; Yau, C. C. T.; Liang, R. H. -S.; Piko, B.; Weber, A.; Kaufman, B.; Drumea, K.; Nuzzo, F.; De Matteis, A.; Nuzzo, F.; Carteni, G.;

Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21). a double-blind, randomised, placebo-controlled, phase 3 trial

2017 - THE LANCET ONCOLOGY

Pujade-Lauraine, E.; Ledermann, J. A.; Selle, F.; Gebski, V.; Penson, R. T.; Oza, A. M.; Korach, J.; Huzarski, T.; Poveda, A.; Pignata, S.; Friedlander, M.; Colombo, N.; Harter, P.; Fujiwara, K.; Ray-Coquard, I.; Banerjee, S.; Liu, J.; Lowe, E. S.; Bloomfield, R.; Pautier, P.; Korach, J.; Huzarski, T.; Byrski, T.; Pautier, P.; Harter, P.; Colombo, N.; Scambia, G.; Nicoletto, M.; Nussey, F.; Clamp, A.; Penson, R.; Oza, A.; Poveda Velasco, A.; Rodrigues, M.; Lotz, J. -P.; Selle, F.; Ray-Coquard, I.; Provencher, D.; Prat Aparicio, A.; Vidal Boixader, L.; Scott, C.; Tamura, K.; Yunokawa, M.; Lisyanskaya, A.; Medioni, J.; Pecuchet, N.; Dubot, C.; de la Motte Rouge, T.; Kaminsky, M. -C.; Weber, B.; Lortholary, A.; Parkinson, C.; Ledermann, J.; Williams, S.; Banerjee, S.; Cosin, J.; Hoffman, J.; Penson, R.; Plante, M.; Covens, A.; Sonke, G.; Joly, F.; Floquet, A.; Banerjee, S.; Hirte, H.; Amit, A.; Park-Simon, T. -W.; Matsumoto, K.; Tjulandin, S.; Kim, J. H.; Gladieff, L.; Sabbatini, R.; O'Malley, D.; Timmins, P.; Kredentser, D.; Lainez Milagro, N.; Barretina Ginesta, M. P.; Tibau Martorell, A.; Gomez de Liano Lista, A.; Ojeda Gonzalez, B.; Mileshkin, L.; Mandai, M.; Boere, I.; Ottevanger, P.; Nam, J. -H.; Filho, E.; Hamizi, S.; Cognetti, F.; Warshal, D.; Dickson-Michelson, E.; Kamelle, S.; Mckenzie, N.; Rodriguez, G.; Armstrong, D.; Chalas, E.; Celano, P.; Behbakht, K.; Davidson, S.; Welch, S.; Helpman, L.; Fishman, A.; Bruchim, I.; Sikorska, M.; Slowinska, A.; Rogowski, W.; Bidzinski, M.; Spiewankiewicz, B.; Casado Herraez, A.; Mendiola Fernandez, C.; Gropp-Meier, M.; Saito, T.; Takehara, K.; Enomoto, T.; Watari, H.; Choi, C. H.; Kim, B. -G.; Kim, J. W.; Hegg, R.; Vergote, I.

Efficacy of two different doses of rabbit anti-t-lymphocyte globulin to prevent graft-versus-host disease in children with haematological malignancies transplanted from an unrelated donor: a multicentre, randomised, open-label, phase 3 trial

2017 - THE LANCET ONCOLOGY

Locatelli, F.; Bernardo, M. E.; Bertaina, A.; Rognoni, C.; Comoli, P.; Rovelli, A.; Pession, A.; Fagioli, F.; Favre, C.; Lanino, E.; Giorgiani, G.; Merli, P.; Pagliara, D.; Prete, A.; Zecca, M.

Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial

2017 - THE LANCET ONCOLOGY

Gronchi, Alessandro; Ferrari, Stefano; Quagliuolo, Vittorio; Broto, Javier Martin; Pousa, Antonio Lopez; Grignani, Giovanni; Basso, Umberto; Blay, Jean-Yves; Tendero, Oscar; Beveridge, Robert Diaz; Ferraresi, Virginia; Lugowska, Iwona; Merlo, Domenico Franco; Fontana, Valeria; Marchesi, Emanuela; Donati, Davide Maria; Palassini, Elena; Palmerini, Emanuela; De Sanctis, Rita; Morosi, Carlo; Stacchiotti, Silvia; BaguÃ£Â©, Silvia; Coindre, Jean Michelle; Dei Tos, Angelo Paolo; Picci, Piero; Bruzzi, Paolo; Casali, Paolo Giovanni

Sentinel-lymph-node mapping in endometrial cancer

2017 - THE LANCET ONCOLOGY

Bogani, G; Ditto, A; Leone Roberti Maggiore, U; Lorusso, D; Raspagliesi, F.

Risk-stratified staging in paediatric hepatoblastoma. A unified analysis from the children's hepatic tumors international collaboration

2017 - THE LANCET ONCOLOGY

Rebecka L, Meyers; Rudolf, Maibach; Eiso, Hiyama; Beate, HÃ¤berle; Mark, Krailo; Arun, Rangaswami; Daniel C, Aronson; Marcio H, Malogolowkin; Perilongo, Giorgio; Dietrich, von Schweinitz; Marc, Ansari; Dolores, Lopez Terrada; Yukichi, Tanaka; Alaggio, Rita; Ivo, Leuschner; Tomoro, Hishiki; Irene, Schmid; Kenichiro, Watanabe; Kenichi, Yoshimura; Yurong, Feng; Eugenia, Rinaldi; Davide, Saraceno; Marisa, Derosa; Piotr, Czauderna

Targeting cancer cachexia: we're on the way

2016 - THE LANCET ONCOLOGY

Muscaritoli, Maurizio

Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): And randomised, phase 3, open-label, multicentre study

2016 - THE LANCET ONCOLOGY

Dimopoulos, Meletios A; Moreau, Philippe; Palumbo, Antonio; Joshua, Douglas; Pour, Ludek; HÃ¡jek, Roman; Facon, Thierry; Ludwig, Heinz; Oriol, Albert; Goldschmidt, Hartmut; RosiÃ±ol, Laura; Straub, Jan; Suvorov, Aleksandr; Araujo, Carla; Rimashevskaya, Elena; Pika, Tomas; Gaidano, Gianluca; Weisel, Katja; Goranova Marinova, Vesselina; Schwarer, Anthony; Minuk, Leonard; Masszi, TamÃ¡s; Karamanesht, Ievgenii; Offidani, Massimo; Hungria, Vania; Spencer, Andrew; Orlowski, Robert Z; Gillenwater, Heidi H; Mohamed, Nehal; Feng, Shibao; Chng, Wee Joo; Endeavor, Investigators; Foa, Roberto

Palbociclib. efficacious but predictive biomarkers still needed

2016 - THE LANCET ONCOLOGY

Cognetti, F.; Malaguti, P.; Alesini, D.

EANO guidelines for the diagnosis and treatment of meningiomas

2016 - THE LANCET ONCOLOGY

Goldbrunner, R.; Minniti, G.; Preusser, M.; Jenkinson, M. D.; Sallabanda, K.; Houdart, E.; von Deimling, A.; Stavrinou, P.; Lefranc, F.; Lund-Johansen, M.; Moyal, E. C. -J.; Brandsma, D.; Henriksson, R.; Soffietti, R.; Weller, M.

FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study

2015 - THE LANCET ONCOLOGY

Cremolini, C; Loupakis, F; Antoniotti, C; Lupi, C; Sensi, E; Lonardi, S; Mezi, Silvia; Tomasello, G; Ronzoni, M; Zaniboni, A; Tonini, G; Carlomagno, C; Allegrini, G; Chiara, S; D'Amico, M; Granetto, C; Cazzaniga, M; Boni, L; Fontanini, G; Falcone, A. 1. 6.

Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study.

2015 - THE LANCET ONCOLOGY

Topp, Ms; GÃ¶kbuget, N; Stein, As; Zugmaier, G; O'Brien, S; Bargou, Rc; Dombret, H; Fielding, Ak; Heffner, L; Larson, Ra; Neumann, S; Foa, Roberto; Litzow, M; Ribera, Jm; Rambaldi, A; Schiller, G; BrÃ¼ggemann, M; Horst, Ha; Holland, C; Jia, C; Maniar, T; Huber, B; Nagorsen, D; Forman, Sj; Kantarjian, H. M.

Prognostic value of self-reported fatigue on overall survival in patients with myelodysplastic syndromes: a multicentre, prospective, observational, cohort study

2015 - THE LANCET ONCOLOGY

Efficace, F; Gaidano, G; Breccia, M; Voso, Mt; Cottone, F; Angelucci, E; Caocci, G; Stauder, R; Selleslag, D; Sprangers, M; Platzbecker, U; Ricco, A; Sanpaolo, G; Beyne-Rauzy, O; Buccisano, F; Palumbo, Ga; Bowen, D; Nguyen, K; Niscola, P; Vignetti, M; Mandelli, F.

Orteronel plus prednisone in patients with chemotherapy-naive metastatic castration-resistant prostate cancer (ELM-PC 4). A double-blind, multicentre, phase 3, randomised, placebo-controlled trial

2015 - THE LANCET ONCOLOGY

Saad, Fred; Fizazi, Karim; Jinga, Viorel; Efstathiou, Eleni; Fong, Peter C; Hart, Lowell L; Jones, Robert; Mcdermott, Raymond; Wirth, Manfred; Suzuki, Kazuhiro; Maclean, David B; Wang, Ling; Akaza, Hideyuki; Nelson, Joel; Scher, Howard I; Dreicer, Robert; Webb, Iain J; de Wit, Ronald; Collaborators, ; Tubaro, Andrea