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Alessandro.Rosa@uniroma1.it
Alessandro Rosa
Professore Associato
Struttura:
DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "CHARLES DARWIN"
E-mail:
Alessandro.Rosa@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Publications
Title
Published on
Year
Direct conversion of human pluripotent stem cells into cranial motor neurons using a piggyBac vector
STEM CELL RESEARCH
2018
Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS
COMMUNICATIONS BIOLOGY
2018
FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons
NATURE COMMUNICATIONS
2017
Role of microRNAs in zygotic genome activation: modulation of mRNA during embryogenesis
Methods in Molecular Biology
2017
Importin-beta and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function
JOURNAL OF CELL SCIENCE
2017
FUS mutant human motoneurons display altered transcriptome and microRNA pathways with implications for ALS pathogenesis
STEM CELL REPORTS
2017
Loss of miR-107, miR-181c and miR-29a-3p promote activation of Notch2 signaling in pediatric high-grade gliomas (pHGGs)
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2017
Long Noncoding RNA Regulation of Pluripotency
STEM CELLS INTERNATIONAL
2016
Mapping the amide I absorption in single bacteria and mammalian cells with resonant infrared nanospectroscopy
NANOTECHNOLOGY
2016
Differentiation of control and ALS mutant human iPSCs into functional skeletal muscle cells, a tool for the study of neuromuscolar diseases
STEM CELL RESEARCH
2016
Divergent lncRNAs take the lead on pluripotent cell differentiation
STEM CELL INVESTIGATION
2016
Protein clustering in chemically stressed HeLa cells studied by infrared nanospectroscopy
NANOSCALE
2016
Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice
Nature CommunicationsNATURE COMMUNICATIONS
2015
N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore-microtubule dynamics
ONCOGENE
2015
ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cells- derived motoneurons
DISEASE MODELS & MECHANISMS
2015
Pur-alpha functionally interacts with FUS carrying ALS-associated mutations
CELL DEATH & DISEASE
2015
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KET
Life-science technologies & biotechnologies
Interessi di ricerca
Keywords
human induced pluripotent stem cells (hiPSC)
microRNA
RNA-binding proteins
motoneuron
amyotrophic lateral sclerosis (ALS)
brain organoid
Progetti di Ricerca
Generation and Coherent Antistokes Raman Scattering (CARS) characterization of a neuromuscular junction for Amyotrophic Lateral Sclerosis in vitro disease modeling
Identification and characterization of RNA binding proteins and non-coding RNAs with a role in human neural specification and neurodegenerative diseases
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