Aurelia Rughetti | Ricerc@Sapienza

Publications

Title	Published on	Year
An ecofriendly iron MOF-based immunosensor for sensitive detection of vascular endothelium growth factor in serum of cancer patients	NANOSCALE	2025
Functional reprogramming of neutrophils within the brain tumor microenvironment by hypoxia-driven histone lactylation	CANCER DISCOVERY	2025
Immunological network signature of naïve non-oncogene-addicted non-small cell lung cancer patients treated with anti-PD1 therapy. A pilot study	CANCERS	2025
Assuring Primary Healthcare Services to Vulnerable Children in a Disadvantaged Suburb of Rome Metropolitan City During the Pandemic: Responses to the Crisis	CHILDREN	2025
MiR-326: Role and significance in brain cancers	NON-CODING RNA RESEARCH	2025
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches	JOURNAL OF EXTRACELLULAR VESICLES	2024
CD137+ and regulatory T cells as independent prognostic factors of survival in advanced non-oncogene addicted NSCLC patients treated with immunotherapy as first-line	JOURNAL OF TRANSLATIONAL MEDICINE	2024
Frequency of brain ventricular enlargement among patients with diabetes mellitus	DIABETES RESEARCH AND CLINICAL PRACTICE	2024
Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma	IMMUNITY	2024
Precision oncology targeting FGFRs: A systematic review on pre-clinical activity and clinical outcomes of pemigatinib	CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY	2024
Imperative role of adaptor proteins in macrophage toll-like receptor signaling pathways	FUTURE SCIENCE OA	2024
Exploring Genomic Biomarkers for Pembrolizumab Response: A Real-World Approach and Patient Similarity Network Analysis Reveal DNA Response and Repair Gene Mutations as a Signature	CANCERS	2024
Anti-PD1 therapies induce an early expansion of Ki67+CD8+ T cells in metastatic non-oncogene addicted NSCLC patients	FRONTIERS IN IMMUNOLOGY	2024
Immune-related toxicity and soluble profile in patients affected by solid tumors: a network approach	CANCER IMMUNOLOGY, IMMUNOTHERAPY	2023
Circulating CD137+ T cell levels are correlated with response to pembrolizumab treatment in advanced head and neck cancer patients	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2023
Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity	JOURNAL OF IMMUNOLOGY RESEARCH	2023
Proteomic characterization of extracellular vesicles released by third stage larvae of the zoonotic parasite Anisakis pegreffii (Nematoda: Anisakidae)	FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY	2023
Macrophage galactose-like lectin mediated interactions: investigating immunosuppressive mechanisms in glioblastoma	www.siica.it	2023
Molecular mechanisms of the tyrosine kinase inhibitor pralsetinib activity in in-vitro models of medullary thyroid carcinoma: Aberrant activation of the HH-Gli signaling pathway in acquired resistance	BIOMÉDECINE & PHARMACOTHÉRAPIE	2023
Sarcopenic obesity research perspectives outlined by the sarcopenic obesity global leadership initiative (SOGLI) - Proceedings from the SOGLI consortium meeting in rome November 2022	CLINICAL NUTRITION	2023

ERC

LS1_6
LS2_10
LS2_15
LS4_12
LS6
LS6_3
LS6_10
LS7_14

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Keywords

dendritic cells

antigen processing and presentation

Cancer vaccines

lectins

tumor antigen

Extracellular Vesicles

anti-tumor immune response

tumor microenvironment

Network medicine

glioblastoma (GBM)

breast cancer

immunogenic cell death (ICD)

ovarian cancer

Progetti di Ricerca

Impact of aberrant O-glycosylation in antigen immune recognition: glycoepitope identification for T cell based anti-cancer immunotherapy
Glioblastoma Multiforme (GBM): investigating the mechanisms by which the tumor glyco-code modulates anti-tumor immunity