high resolution mass spectrometry

Bioinorganic chemistry and mass spectrometry

Bioinorganic chemistry and mass spectrometry

Processi chimici e biochimici di fondamentale importanza che avvengono in soluzione frequentemente procedono tramite specie ioniche che agiscono come intermedi elusivi. La spettrometria di massa (MS) offre uno strumento potente per intercettare e manipolare queste specie, permettendo così di ottenere informazioni sul loro ruolo. Informazioni strutturali possono essere ottenute tramite esperimenti di dissociazione indotta da collisione (CID), reazioni ione-molecola e spettroscopia vibrazionale delle specie ioniche gassose campionate, tramite spettroscopia ionica IR.

Cutting-Edge Molecular Approaches for Cultural Heritage - From Paleoproteomics to Advanced SERS Sensors, the Next-Gen Analytical Technologies

Cutting-Edge Molecular Approaches for Cultural Heritage - From Paleoproteomics to Advanced SERS Sensors, the Next-Gen Analytical Technologies

Professor Favero’s group is dedicated to pioneering advanced technologies at the intersection of science and cultural heritage. Their research spans the creation of cutting-edge active SERS substrates for ultra-sensitive detection and identification of pollutants in museum environments, development of innovative nanomaterials up to new advanced methodology in paleoproteomics and study of ancient organic residues using integrated omics approaches.

HRMS-Omics Lab

HRMS-Omics Lab

The HRMS-Omics Lab is a state-of-the-art analytical facility specializing in metabolomics, lipidomics, and peptidomics across biological and food matrices. Equipped with high-resolution Orbitrap platforms (Q-Exactive and Orbitrap Elite), the laboratory delivers comprehensive molecular profiling with exceptional mass accuracy, sensitivity, and structural elucidation capability.

Envi-Food lab: Qualità e sicurezza in ambito alimentare e ambientale

Envi-Food lab: Qualità e sicurezza in ambito alimentare e ambientale

Il gruppo ha una consolidata esperienza nello sviluppo e nell’ottimizzazione di metodi analitici avanzati basati sulla cromatografia liquida accoppiata alla spettrometria di massa tandem (UHPLC-MS/MS), sia a bassa sia ad alta risoluzione.

Green Lab

Green Lab

Il gruppo di ricerca si concentra sullo sviluppo di metodi analitici sostenibili in linea con i principi della Green Analytical Chemistry (GAC), con particolare attenzione alla valorizzazione di fonti di riciclo e alla riduzione dell’impatto ambientale dei processi analitici.

Italian Centre for Native Mass Spectrometry - INCENTIVE MS

Italiano

Native MS is a non-denaturing technique which allows to preserve noncovalent interactions and quaternary protein structure in the gas phase. Unlike conventional denaturing MS, which often includes organic solvents and low pH, native MS uses volatile, aqueous buffers at near physiological pH and gentler temperatures and voltages. This enables the study of protein-protein interactions, protein-ligand interactions, subunit architecture, and complex stoichiometry.

Multi-residue Ultra Performance Liquid Chromatography-High resolution mass spectrometric method for the analysis of 21 cyanotoxins in surface water for human consumption

The presence of cyanobacteria and their toxins in water used as drinking water or for recreational purposes may represent a risk for human health. This work describes the development of an advanced analytical method for simultaneous determination of 21 cyanotoxins (including Microcystins, Cyanopeptolins, Anabaenopeptins and Microginins) in drinking water based on Ultra Performance Liquid Chromatography coupled with a Q-TOF mass spectrometer.

Nanoemulsions of Satureja montana essential oil. Antimicrobial and antibiofilm activity against avian Escherichia coli strains

Satureja montana essential oil (SEO) presents a wide range of biological activities due to its high content of active phytochemicals. In order to improve the essential oil’s (EO) properties, oil in water nanoemulsions (NEs) composed of SEO and Tween-80 were prepared, characterized, and their antimicrobial and antibiofilm properties assayed against Escherichia coli strains isolated from healthy chicken.

An ultra performance liquid chromatography coupled with high resolution mass spectrometry method for the screening of cianotoxins content in drinking water samples

The incidence of cyanobacterial harmful algal blooms (CHABs) and their potentially toxic secondary metabolites is increasing in Italy and worldwide and several studies demonstrated that the climate change may be playing a role. The method described in this work allows to detect simultaneously 21 cyanotoxins of different classes (including 12 Microcystins, 5 Microginins, 2 Cyanopeptolins, and 2 Anabaenopeptins) in water samples for human consumption by an Ultra Performance Liquid Chromatography coupled with a Q-TOF mass spectrometer.

Peptidomic strategy for purification and identification of potential ACE-inhibitory and antioxidant peptides in tetradesmus obliquus microalgae

Microalgae are unicellular marine organisms that have promoted complex biochemical pathways to survive in greatly competitive marine environments. They could contain significant amounts of high-quality proteins which, because of their structural diversity, contain a range of yet undiscovered novel bioactive peptides. In this work, a peptidomic platform was developed for the separation and identification of bioactive peptides in protein hydrolysates.

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