Ricerc@Sapienza

Our research group is interested in the regulation of VitaminB6 metabolism in bacteria and humans, and in diseases caused by Vitamin B6 malfunctioning.

Specifically, our studies focus on:

i) Transcriptional regulation of Vitamin $\text{B}_6$ metabolism in bacteria;

ii) Allosteric properties of proteins involved in Vitamin $\text{B}_6$ metabolism in bacteria and humans;

iii) Molecular basis of neurological diseases caused by defects in Vitamin $\text{B}_6$ metabolism;

iv) Targeted inhibition of Vitamin $\text{B}_6$ metabolism as an anti-cancer strategy."