Risultati ricerca pubblicazioni

An innovative method for quantification of basic sites linked on solid matrices

pubblicato su: Book of abstracts Merck Young Chemists’ Symposium XIX edition - 2019

Buonsenso Fabio, Manzi Giuliana, Ismail Omar H., Ciogli Alessia, Siani Gabriella, Pierini Marco

Synthesis of pyrano[2,3-: F] chromen-2-ones vs. pyrano[3,2-g] chromen-2-ones through site controlled gold-catalyzed annulations

pubblicato su: ORGANIC & BIOMOLECULAR CHEMISTRY - 2019

Arcadi A., Ciogli A., Fabrizi G., Fochetti A., Franzini R., Ghirga F., Goggiamani A., Iazzetti A.

Enantioselective ultra high performance liquid and supercritical fluid chromatography: the race to the shortest chromatogram

pubblicato su: JOURNAL OF SEPARATION SCIENCE - 2018

Ciogli Alessia, Ismail Omar H., Mazzoccanti Giulia, Villani Claudio, Gasparrini Francesco

Recognition mechanism of aromatic derivatives resolved by argentation chromatography: The driving role played by substituent groups

pubblicato su: ANALYTICA CHIMICA ACTA - 2018

Menta Sergio, Ciogli Alessia, Villani Claudio, Gasparrini Francesco, Pierini Marco

Stepwise “bridge-to-bridge” reduction of monoclonal antibodies and light chain detection: case studies of tenatumomab and trastuzumab

pubblicato su: SEPARATION SCIENCE PLUS - 2018

Mazzoccanti Giulia, Pierri Giuseppe, Ciogli Alessia, Ismail Omar H., Giorgi Fabrizio, De Santis Rita, Villani Claudio, Gasparrini Francesco

Synthesis of bromoundecyl resorc[4]arenes and applications of the cone stereoisomer as selector for liquid chromatography

pubblicato su: JOURNAL OF ORGANIC CHEMISTRY - 2018

Corradi Silvia, Mazzoccanti Giulia, Ghirga Francesca, Quaglio Deborah, Nevola Laura, Massera Chiara, Ugozzoli Franco, Giannini Giuseppe, Ciogli Alessia, D'Acquarica Ilaria

Recent developments in chiral separations by supercritical fluid chromatography

pubblicato su: Chiral Analysis (Second Edition) - 2018

Franzini Roberta, Ciogli Alessia, Gasparrini Francesco, Ismail Omar H., Villani Claudio

Aggregation behaviour of triphenylphosphonium bolaamphiphiles

pubblicato su: JOURNAL OF COLLOID AND INTERFACE SCIENCE - 2018

Ceccacci Francesca, Sennato Simona, Rossi Edoardo, Proroga Raffaele, Sarti Stefano, Diociaiuti Marco, Casciardi Stefano, Mussi Valentina, Ciogli Alessia, Bordi Federico, Mancini Giovanna, Bombelli Cecilia

Unmatched kinetic performance in enantioselective supercritical fluid chromatography by combining latest generation whelk-O1 chiral stationary phases with a low-dispersion in-house modified equipment

pubblicato su: ANALYTICAL CHEMISTRY - 2018

Ismail Omar H., Losacco Gioacchino L., Mazzoccanti Giulia, Ciogli Alessia, Villani Claudio, Catani Martina, Pasti Luisa, Anderson Scott, Cavazzini Alberto, Gasparrini Francesco

Copper-catalyzed C-N bond formation via C-H functionalization: facile synthesis of multisubstituted imidazo[1,2- a ]pyridines from N -(2-pyridinyl)enaminones

pubblicato su: SYNTHESIS - 2018

Cacchi Sandro, Ciogli Alessia, Demitri Nicola, Fabrizi Giancarlo, Ghirga Francesca, Goggiamani Antonella, Iazzetti Antonia, Lamba Doriano

Direct analysis of chiral active pharmaceutical ingredients and their counterions by ultra high performance liquid chromatography with macrocyclic glycopeptide-based chiral stationary phases

pubblicato su: JOURNAL OF CHROMATOGRAPHY A - 2018

Ismail Omar H., Antonelli Michela, Ciogli Alessia, De Martino Michela, Catani Martina, Villani Claudio, Cavazzini Alberto, Ye Michael, Bell David S., Gasparrini Francesco

Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2020

Puxeddu M., Shen H., Bai R., Coluccia A., Nalli M., Mazzoccoli C., Da Pozzo E., Cavallini C., Martini C., Orlando V., Biagioni S., Mazzoni C., Coluccia A. M. L., Hamel E., Liu T., Silvestri R., La Regina G.

Discovery of Zika virus NS2B/NS3 inhibitors that prevent mice from fife-threatening infection and brain damage

pubblicato su: ACS MEDICINAL CHEMISTRY LETTERS - 2020

Coluccia A., Puxeddu M., Nalli M., Wei C. K., Wu Y. H., Mastrangelo E., Elamin T., Tarantino D., Bugert J. J., Schreiner B., Nolte J., Schwarze F., La Regina G., Lee J. C., Silvestri R.

New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2020

Nalli M., Armijos Rivera J. I., Masci D., Coluccia A., Badia R., Riveira-Muñoz E., Brambilla A., Cinquina E., Turriziani O., Falasca F., Catalano M., Limatola C., Esté J. A., Maga G., Silvestri R., Crespan E., La Regina G.

Enzymatic kinetic resolution of desmethylphosphinothricin indicates that phosphinic group is a bioisostere of carboxyl group

pubblicato su: COMMUNICATIONS CHEMISTRY - 2020

De Biase Daniela, Cappadocio Francesca, Pennacchietti Eugenia, Giovannercole Fabio, Coluccia Antonio, Vepsäläinen Jouko, Khomutov Alex

Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics

pubblicato su: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN - 2020

Bufano M., Laudette M., Blondeau J. -P., Lezoualc'h F., Nalli M., Silvestri R., Brancale A., Coluccia A.

Towards modern anticancer agents that interact with tubulin

pubblicato su: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES - 2019

La Regina G., Coluccia A., Naccarato V., Silvestri R.

Nox2-mediated platelet activation by glycoprotein (GP) VI: Effect of rivaroxaban alone and in combination with aspirin

pubblicato su: BIOCHEMICAL PHARMACOLOGY - 2019

Cammisotto Vittoria, Carnevale Roberto, Nocella Cristina, Stefanini Lucia, Bartimoccia Simona, Coluccia Antonio, Silvestri Romano, Pignatelli Pasquale, Pastori Daniele, Violi Francesco

Small molecule inhibitors of KDM5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing Jarid1b

pubblicato su: MOLECULES - 2019

Pippa S, Mannironi C, Licursi V, BOMBARDI LUCA, Colotti G, Cundari E, Mollica A, Coluccia A, Naccarato V, La Regina G, Silvestri R, Negri R

Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: structure-activity relationships and mode of action studies

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2019

Masci D., Hind C., Islam M. K., Toscani A., Clifford M., Coluccia A., Conforti Irene, Touitou M., Memdouh S., Wei X., La Regina G., Silvestri R., Sutton J. M., Castagnolo D.

Identification of a pharmacological inhibitor of Epac1 that protects the heart against acute and chronic models of cardiac stress

pubblicato su: CARDIOVASCULAR RESEARCH - 2019

Laudette Marion, Coluccia Antonio, Sainte-Marie Yannis, Solari Andrea, Fazal Loubina, Sicard Pierre, Silvestri Romano, Mialet-Perez Jeanne, Pons Sandrine, Ghaleh Bijan, Blondeau Jean-Paul, Frank Lezoualc’h And

β-catenin knockdown promotes nherf1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy

pubblicato su: ONCOGENE - 2018

Saponaro Concetta, Sergio Sara, Coluccia Antonio, De Luca Maria, LA REGINA Giuseppe, Mologni Luca, Famiglini Valeria, Naccarato Valentina, Bonetti Daniela, Gautier CANDICE NATACHA ANNA, Gianni Stefano, Vergara Daniele, Salzet Michel, Fournier Isabelle, Bucci Cecilia, Silvestri Romano, Gambacorti Passerini Carlo, Maffia Michele, Maria Luce Coluccia Addolorata

New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors

pubblicato su: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - 2018

La Regina Giuseppe, Bai Ruoli, Coluccia Antonio, Naccarato Valentina, Famiglini Valeria, Nalli Marianna, Masci Domiziana, Verrico Annalisa, Rovella Paola, Mazzoccoli Carmela, Da Pozzo Eleonora, Cavallini Chiara, Martini Claudia, Vultaggio Stefania, Dondio Giulio, Varasi Mario, Mercurio Ciro, Hamel Ernest, Lavia Patrizia, Silvestri Romano

Treating chronic myeloid leukemia by inhibition of tubulin polymerization

pubblicato su: Book of Abstracts - 2018

LA REGINA Giuseppe, Coluccia Antonio, Naccarato Valentina, Maria Luce Coluccia Addolorata, Hamel Ernest, Novellino Ettore, Silvestri Romano

Structure-based drug design of potent pyrazole derivatives against Rhinovirus replication

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2018

Da Costa L., Scheers E., Coluccia A., Casulli A., Roche M., Di Giorgio C., Neyts J., Terme T., Cirilli R., La Regina G., Silvestri R., Mirabelli C., Vanelle P.

Indolylarylsulfones as novel potent anti-HIV-1 agents

pubblicato su: Book of Abstract - 2018

Masci Domiziana, LA REGINA Giuseppe, Coluccia Antonio, Brancale Andrea, Esté José A., Silvestri Romano

Discovery of a pyrimidine compound endowed with antitumor activity

pubblicato su: INVESTIGATIONAL NEW DRUGS - 2020

Taglieri Ludovica, Saccoliti Francesco, Nicolai Alice, Peruzzi Giovanna, Madia Valentina Noemi, Tudino Valeria, Messore Antonella, Di Santo Roberto, Artico Marco, Taurone Samanta, Salvati Maurizio, Costi Roberta, Scarpa Susanna

Influence of oral administration mode on the efficacy of commercial bovine Lactoferrin against iron and inflammatory homeostasis disorders

pubblicato su: BIOMETALS - 2020

Rosa L., Lepanto M. S., Cutone A., Siciliano R. A., Paesano R., Costi R., Musci G., Valenti P.

In vitro antiviral activity of new oxazoline derivatives as potent poliovirus inhibitors

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2019

Madia Valentina Noemi, Messore Antonella, Pescatori Luca, Saccoliti Francesco, Tudino Valeria, De Leo Alessandro, Scipione Luigi, Fiore Lucia, Rhoden Eric, Manetti Fabrizio, Oberste M Steven, Di Santo Roberto, Costi Roberta

Inhibition of Polycomb Repressive Complex2 activity reduces trimethylation of H3K27 and affects development in Arabidopsis seedlings

pubblicato su: BMC PLANT BIOLOGY - 2019

Ruta Veronica, Longo Chiara, Boccaccini Alessandra, Madia VALENTINA NOEMI, Saccoliti Francesco, Tudino Valeria, DI SANTO Roberto, Lorrai Riccardo, DELLO IOIO Raffaele, Sabatini Sabrina, Costi Roberta, Costantino Paolo, Vittorioso Paola

Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism

pubblicato su: AMINO ACIDS - 2019

Colotti G., Saccoliti F., Gramiccia M., Di Muccio T., Prakash J., Yadav S., Dubey V. K., Vistoli G., Battista T., Mocci S., Fiorillo A., Bibi A., Madia V. N., Messore A., Costi R., Di Santo R., Ilari A.

Structure-guided approach identifies a novel class of HIV-1 ribonuclease H inhibitors: binding mode insights through magnesium complexation and site-directed mutagenesis studies

pubblicato su: MEDCHEMCOMM - 2018

Poongavanam Vasanthanathan, Corona Angela, Steinmann Casper, Scipione Luigi, Grandi Nicole, Pandolfi Fabiana, Di Santo Roberto, Costi Roberta, Esposito Francesca, Tramontano Enzo, Kongsted Jacob

Novel benzazole derivatives endowed with potent antiheparanase activity

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2018

Madia VALENTINA NOEMI, Messore Antonella, Pescatori Luca, Saccoliti Francesco, Tudino Valeria, DE LEO Alessandro, Bortolami Martina, Scipione Luigi, Costi Roberta, Rivara Silvia, Scalvini Laura, Mor Marco, Fosca Ferrara Fabiana, Pavoni Emiliano, Roscilli Giuseppe, Cassinelli Giuliana, M Milazzo Ferdinando, Battistuzzi Gianfranco, DI SANTO Roberto, Giannin Giuseppe

Glycerol as a green solvent for enhancing the formulation of dextran methacrylate and gellan-based semi-interpenetrating polymer networks

pubblicato su: JOURNAL OF MATERIALS SCIENCE - 2020

Zoratto Nicole, Matassa Roberto, Montanari Elita, Familiari Giuseppe, Petralito Stefania, Coviello Tommasina, Di Meo Chiara, Matricardi Pietro

Halting hyaluronidase activity with hyaluronan-based nanohydrogels: development of versatile injectable formulations

pubblicato su: CARBOHYDRATE POLYMERS - 2019

Montanari E., Zoratto N., Mosca L., Cervoni L., Lallana E., Angelini R., Matassa R., Coviello T., Di Meo C., Matricardi P.

Intracellular delivery of natural antioxidants via hyaluronan nanohydrogels

pubblicato su: PHARMACEUTICS - 2019

Montanari E., Di Meo C., Coviello T., Gueguen V., Pavon-Djavid G., Matricardi P.

Hyaluronan-Based Nanohydrogels for Targeting Intracellular S. Aureus in Human Keratinocytes

pubblicato su: ADVANCED HEALTHCARE MATERIALS - 2018

Montanari Elita, Oates Angela, Di Meo Chiara, Meade Josephine, Cerrone Rugiada, Francioso Antonio, Devine Deirdre, Coviello Tommasina, Mancini Patrizia, Mosca Luciana, Matricardi Pietro

Pursuing intracellular pathogens with hyaluronan. From a 'pro-infection' polymer to a biomaterial for 'trojan horse' systems

pubblicato su: MOLECULES - 2018

Montanari Elita, Di Meo Chiara, Oates Angela, Coviello Tommasina, Matricardi Pietro

Long-circulating hyaluronan-based nanohydrogels as carriers of hydrophobic drugs

pubblicato su: PHARMACEUTICS - 2018

Di Meo C., Martinez-Martinez M., Coviello T., Bermejo M., Merino V., Gonzalez-Alvarez I., Gonzalez-Alvarez M., Matricardi P.

A multi-methodological inquiry of the behavior of cisplatin-based Pt(IV) derivatives in the presence of bioreductants with a focus on the isolated encounter complexes

pubblicato su: JBIC - 2020

Corinti D., Crestoni M. E., Fornarini S., Dabbish E., Sicilia E., Gabano E., Perin E., Osella D.

Satureja montana L. essential oil and its antimicrobial activity alone or in combination with gentamicin

pubblicato su: MICROBIAL PATHOGENESIS - 2019

Vitanza Luca, Maccelli Alessandro, Marazzato Massimiliano, Scazzocchio Francesca, Comanducci Antonella, Fornarini Simonetta, Crestoni Maria Elisa, Filippi Antonello, Fraschetti Caterina, Rinaldi Federica, Aleandri Marta, Goldoni Paola, Conte Maria Pia, Ammendolia Maria Grazia, Longhi Catia

The dramatic effect of N-methylimidazole on trans axial ligand binding to ferric heme: experiment and theory

pubblicato su: PHYSICAL CHEMISTRY CHEMICAL PHYSICS - 2019

Aarabi Mohammad, Omidyan Reza, Soorkia Satchin, Grégoire Gilles, Broquier Michel, Crestoni Maria-Elisa, de la Lande Aurélien, Soep Benoît, Shafizadeh Niloufar

An integrated approach to study novel properties of a MALDI matrix (4-maleicanhydridoproton sponge) for MS imaging analyses

pubblicato su: ANALYTICAL AND BIOANALYTICAL CHEMISTRY - 2019

Corinti Davide, Crestoni Maria Elisa, Fornarini Simonetta, Pieper Maren, Niehaus Karsten, Giampà Marco

L-Cysteine modified by S-Sulfation: consequence on fragmentation processes elucidated by tandem mass spectrometry and chemical dynamics simulations

pubblicato su: JOURNAL OF PHYSICAL CHEMISTRY. A, MOLECULES, SPECTROSCOPY, KINETICS, ENVIRONMENT, & GENERAL THEORY - 2019

Macaluso Veronica, Scuderi Debora, Crestoni Maria Elisa, Fornarini Simonetta, Corinti Davide, Dalloz Enzo, Martinez-Nunez Emilio, Hase William L., Spezia Riccardo