Risultati ricerca pubblicazioni

Epigenetic Pharmacology in Regenerative Medicine (Epi-Drugs)

pubblicato su: Epigenetics and Regeneration - 2019

STAZI Giulia, ZWERGEL CLEMENS, VALENTE Sergio, MAI Antonello

Amphetamine and the Smart Drug 3,4-Methylenedioxypyrovalerone (MDPV) Induce Generalization of Fear Memory in Rats

pubblicato su: FRONTIERS IN MOLECULAR NEUROSCIENCE - 2019

Colucci Paola, Mancini Giulia Federica, Santori Alessia, Zwergel Clemens, Mai Antonello, Trezza Viviana, Roozendaal Benno, Campolongo Patrizia

Structure-reactivity relationships on substrates and inhibitors of the lysine deacylase sirtuin 2 from schistosoma mansoni (SmSirt2)

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2019

Monaldi Daria, ROTILI Dante, Julien Lancelot ‡, Martin Marek §, Nathalie Wössner ∥, Lucidi Alessia, TOMASELLI DANIELA, Elizabeth Ramos-Morales ‡, Christophe Romier ∥, Pierce ∥ Raymond J., MAI Antonello, and Manfred Jung ‡

Epigenetic polypharmacology: a new frontier for epi-drug discovery

pubblicato su: MEDICINAL RESEARCH REVIEWS - 2019

TOMASELLI DANIELA, Lucidi Alessia, ROTILI Dante, MAI Antonello

α,γ-Diketocarboxylic acids and their esters act as carbonic anhydrase IX and XII selective inhibitors

pubblicato su: ACS MEDICINAL CHEMISTRY LETTERS - 2019

Nocentini Alessio, Lucidi Alessia, Perut Francesca, Massa Annamaria, TOMASELLI DANIELA, Gratteri Paola, Baldini Nicola, ROTILI Dante, MAI Antonello, Supuran Claudiu T.

DNA Methylation: Biological Implications and Modulation of Its Aberrant Dysregulation

pubblicato su: The DNA, RNA, and Histone Methylomes - 2019

Lucidi Alessia, TOMASELLI DANIELA, ROTILI Dante, MAI Antonello

Inhibition of histone demethylases LSD1 and UTX regulates ERα signaling in breast cancer

pubblicato su: CANCERS - 2019

Benedetti R., Dell'Aversana C., De Marchi T., Rotili D., Liu N. Q., Novakovic B., Boccella S., Di Maro S., Cosconati S., Baldi A., Nimeus E., Schultz J., Hoglund U., Maione S., Papulino C., Chianese U., Iovino F., Federico A., Mai A., Stunnenberg H. G., Nebbioso A., Altucci L.

Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

pubblicato su: CLINICAL EPIGENETICS - 2019

Was H., Krol S. K., Rotili D., Mai A., Wojtas B., Kaminska B., Maleszewska M.

Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells

pubblicato su: EUROPEAN JOURNAL OF PHARMACOLOGY - 2019

Sirotkin A. V., Adamcova E., Rotili D., Mai A., Mlyncek M., Mansour L., Alwasel S., Harrath A. H.

H19-dependent transcriptional regulation of β3 and β4 integrins upon estrogen and hypoxia favors metastatic potential in prostate cancer

pubblicato su: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2019

Bacci L., Aiello A., Ripoli C., Loria R., Pugliese D., Pierconti F., Rotili D., Strigari L., Pinto F., Bassi P. F., Mai A., Grassi C., Pontecorvi A., Falcioni R., Farsetti A., Nanni S.

The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells

pubblicato su: SCIENTIFIC REPORTS - 2019

Favia A., Salvatori L., Nanni S., Iwamoto-Stohl L. K., Valente S., Mai A., Scagnoli F., Fontanella R. A., Totta P., Nasi S., Illi B.

Statins and histone deacetylase inhibitors affect lamin A/C - histone deacetylase 2 interaction in human cells

pubblicato su: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY - 2019

Mattioli Elisabetta, Andrenacci Davide, Mai Antonello, Valente Sergio, Robijns Joke, De Vos Winnok H, Capanni Cristina, Lattanzi Giovanna

Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches

pubblicato su: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN - 2018

Sabatino Manuela, Rotili Dante, Patsilinakos Alexandros, Forgione Mariantonietta, Tomaselli Daniela, Alby Fréderic, Arimondo Paola B., Mai Antonello, Ragno Rino

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

pubblicato su: NATURE COMMUNICATIONS - 2018

Kalin Jay H., Wu Muzhou, Gomez Andrea V., Song Yun, Das Jayanta, Hayward Dawn, Adejola Nkosi, Wu Mingxuan, Panova Izabela, Chung Hye Jin, Kim Edward, Roberts Holly J., Roberts Justin M., Prusevich Polina, Jeliazkov Jeliazko R., Roy Burman Shourya S., Fairall Louise, Milano Charles, Eroglu Abdulkerim, Proby Charlotte M., Dinkova-Kostova Albena T., Hancock Wayne W., Gray Jeffrey J., Bradner James E., Valente Sergio, Mai Antonello, Anders Nicole M., Rudek Michelle A., Hu Yong, Ryu Byungwoo, Schwabe John W. R., Mattevi Andrea, Alani Rhoda M., Cole Philip A.

RIP1-HAT1-SirT complex identification and targeting in treatment and prevention of cancer

pubblicato su: CLINICAL CANCER RESEARCH - 2018

Carafa Vincenzo, Nebbioso Angela, Cuomo Francesca, Rotili Dante, Cobellis Gilda, Bontempo Paola, Baldi Alfonso, Spugnini Enrico P., Citro ALFONSO GENNARO, Chambery Angela, Russo Rosita, Ciana Paolo, Maravigna Luca, Shaik Jani, Radaelli Enrico, De Antonellis Pasquale, Tarantino Domenico, Pirolli Adele, Ragno Rino, Massimo Zollo ., Stunnenberg Hendrik G., Mai Antonello, Altucci Lucia

KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2

pubblicato su: CLINICAL EPIGENETICS - 2018

Cocco Elisa, Leo Manuela, Canzonetta Claudia, Di Vito Serena, Mai Antonello, Rotili Dante, Di Napoli Arianna, Vecchione Andrea, De Nunzio Cosimo, Filetici Patrizia, Stoppacciaro Antonella

Effects of class II-selective histone deacetylase inhibitor on neuromuscular function and disease progression in SOD1-ALS mice

pubblicato su: NEUROSCIENCE - 2018

Buonvicino Daniela, Felici Roberta, Ranieri Giuseppe, Caramelli Riccardo, Lapucci Andrea, Cavone Leonardo, Muzzi Mirko, Di Pietro Lorena, Bernardini Camilla, Zwergel Clemens, Valente Sergio, Mai Antonello, Chiarugi Alberto

Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications

pubblicato su: FUTURE MEDICINAL CHEMISTRY - 2018

Fiorentino Francesco, Mai Antonello, Rotili Dante

Trends of LSD1 inhibitors in viral infections

pubblicato su: FUTURE MEDICINAL CHEMISTRY - 2018

Zwergel Clemens, Stazi Giulia, Mai Antonello, Valente Sergio

Combined HAT/EZH2 modulation leads to cancer-selective cell death

pubblicato su: ONCOTARGET - 2018

Petraglia Francesca, Singh Abhishek A., Carafa Vincenzo, Nebbioso Angela, Conte Mariarosaria, Scisciola Lucia, Valente Sergio, Baldi Alfonso, Mandoli Amit, Petrizzi Valeria Belsito, Ingenito Concetta, De Falco Sandro, Cicatiello Valeria, Apicella Ivana, Janssen-Megens Eva M., Kim Bowon, Yi Guoqiang, Logie Colin, Heath Simon, Ruvo Menotti, Wierenga Albertus T. J., Flicek Paul, Yaspo Marie Laure, Della Valle Veronique, Bernard Olivier, Tomassi Stefano, Novellino Ettore, Feoli Alessandra, Sbardella Gianluca, Gut Ivo, Vellenga Edo, Stunnenberg Hendrik G., Mai Antonello, Martens Joost H. A., Altucci Lucia

Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia

pubblicato su: ONCOTARGET - 2018

Singh Abhishek A., Petraglia Francesca, Nebbioso Angela, Yi Guoqiang, Conte Mariarosaria, Valente Sergio, Mandoli Amit, Scisciola Lucia, Lindeboom Rik, Kerstens Hinri, Janssen-Megens Eva M., Pourfarzad Farzin, Habibi Ehsan, Berentsen Kim, Kim Bowon, Logie Colin, Heath Simon, Wierenga Albertus T. J., Clarke Laura, Flicek Paul, Jansen Joop H., Kuijpers Taco, Yaspo Marie Laure, Della Valle Veronique, Bernard Olivier, Gut Ivo, Vellenga Edo, Stunnenberg Hendrik G., Mai Antonello, Altucci Lucia, Martens Joost H. A.

Epigenetic metalloenzymes

pubblicato su: CURRENT MEDICINAL CHEMISTRY - 2018

Blanquart Christophe, Linot Camille, Cartron Pierre-Francois, Tomaselli Daniela, Mai Antonello, Bertrand Philippe

Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers

pubblicato su: PSYCHOPHARMACOLOGY - 2018

Muñoz-Cobo I., Erburu M. M., Zwergel C., Cirilli R., Mai A., Valente S., Puerta E., Tordera Rosa M.

Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS

pubblicato su: AGING CELL - 2018

Mattioli Elisabetta, Andrenacci Davide, Garofalo Cecilia, Prencipe Sabino, Scotlandi Katia, Remondini Daniel, Gentilini Davide, Di Blasio Anna Maria, Valente Sergio, Scarano Emanuela, Cicchilitti Lucia, Piaggio Giulia, Mai Antonello, Lattanzi Giovanna

A quinoline-based DNA methyltransferase inhibitor as a possible adjuvant in osteosarcoma therapy

pubblicato su: MOLECULAR CANCER THERAPEUTICS - 2018

Manara Maria Cristina, Valente Sergio, Cristalli Camilla, Nicoletti Giordano, Landuzzi Lorena, Zwergel Clemens, Mazzone Roberta, Stazi Giulia, Arimondo Paola B., Pasello Michela, Guerzoni Clara, Picci Piero, Nanni Patrizia, Lollini Pier-Luigi, Mai Antonello, Scotlandi Katia

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

pubblicato su: CELL DEATH & DISEASE - 2018

Iachettini Sara, Trisciuoglio Daniela, Rotili Dante, Lucidi Alessia, Salvati Erica, Zizza Pasquale, Di Leo Luca, Del Bufalo Donatella, Rosa Ciriolo Maria, Leonetti Carlo, Steegborn Clemens, Mai Antonello, Rizzo Angela, Annamaria Biroccio And

Tetra-2,3-pyrazinoporphyrazines with peripherally appended pyridine rings. 19. Pentanuclear octa(2-pyridyl)tetrapyrazinoporphyrazines carrying externally carboranthiolate groups: physicochemical properties and potentialities as anticancer drugs

pubblicato su: INORGANIC CHEMISTRY - 2019

Viola Elisa, Donzello Maria Pia, Testani Silvia, Luccisano Giulia, Astolfi Maria Luisa, Rizzoli Corrado, Cong Lei, Mannina Luisa, Ercolani Claudio, Kadish Karl. M.

Metabolite characterization of powdered fruits and leaves from Adansonia digitata L. (baobab): a multi-methodological approach

pubblicato su: FOOD CHEMISTRY - 2019

Tsetegho Sokeng Arold Jorel, Sobolev Anatoly P., Di Lorenzo Arianna, Xiao Jianbo, Mannina Luisa, Capitani Donatella, Daglia Maria

Multiple Assignment Recovered Analysis (MARA) NMR for a Direct Food Labeling: the Case Study of Olive Oils

pubblicato su: FOOD ANALYTICAL METHODS - 2019

Rotondo Archimede, Mannina Luisa, Salvo Andrea

Evolution of physicochemical properties of pear during drying by conventional techniques, portable-NMR, and modelling

pubblicato su: JOURNAL OF FOOD ENGINEERING - 2018

Proietti Noemi, Adiletta Giuseppina, Russo Paola, Buonocore Renato, Mannina Luisa, Crescitelli Alessio, Capitani Donatella

Combining amplicon sequencing and metabolomics in cirrhotic patients highlights distinctive microbiota features involved in bacterial translocation, systemic inflammation and hepatic encephalopathy

pubblicato su: SCIENTIFIC REPORTS - 2018

Iebba Valerio, Guerrieri Francesca, Di Gregorio Vincenza, Levrero Massimo, Gagliardi Antonella, Santangelo Floriana, Sobolev Anatoly P, Circi Simone, Giannelli Valerio, Mannina Luisa, Schippa Serena, Merli Manuela

Polyphenols fingerprinting in olive oils through maximum-quantum NMR spectroscopy

pubblicato su: FOOD ANALYTICAL METHODS - 2018

Manjunatha Reddy G. N., Mannina Luisa, Sobolev Anatoly P., Caldarelli Stefano

Age-dependent changes in metabolic profile of turkey spermatozoa as assessed by NMR analysis

pubblicato su: PLOS ONE - 2018

Iaffaldano Nicolaia, Di Iorio Michele, Mannina Luisa, Paventi Gianluca, Pina Rosato Maria, Cerolini Silvia, Sobolev Anatoly P.

A proteometabolomic study of Actinidia deliciosa fruit development

pubblicato su: JOURNAL OF PROTEOMICS - 2018

Maria Salzano Anna, Sobolev Anatoly, Carbone Virginia, Petriccione Milena, Renzone Giovanni, Capitani Donatella, Vitale Monica, Minasi Paola, Silvia Pasquariello Maria, Novi Gianfranco, Zambrano Nicola, Scortichini Marco, Mannina Luisa, Scaloni Andrea

Caratterizzazione chemiometrica di composti bioattivi nelle nuove cultivars di pomodori del Lazio: Bamano, Dolce Miele e Confettino Rosso.

pubblicato su: Atti del Congresso AISME 2018 - 2018

Rapa M., Ciano S., Mannina L., Vinci G.

Caratterizzazione della faina di canapa (Cannabis sativa L.): profilo metabolomico e composti bioattivi

pubblicato su: Atti dell'11° Convegno AISTEC - I cereali per un sistema agroalimentare di qualità - 2018

Rapa Mattia, Circi Simone, Sobolev Anatoly, Mannina Luisa, Vinci Giuliana

Supramolecular gels of cholesterol-modified gellan gum with disc-like and worm-like micelles

pubblicato su: JOURNAL OF COLLOID AND INTERFACE SCIENCE - 2019

Zoratto N., Grillo I., Matricardi P., Dreiss C. A.

Nanodesign of new self-assembling core-shell gellan-transfersomes loading baicalin and in vivo evaluation of repair response in skin

pubblicato su: NANOMEDICINE - 2018

Manconi Maria, Manca Maria Letizia, Caddeo Carla, Valenti Donatella, Cencetti Claudia, Diez-Sales Octavio, Nacher Amparo, Mir-Palomo Silvia, Terencio Maria Carmen, Demurtas Davide, Gomez-Fernandez Juan Carmelo, Aranda Francisco JosÃ©, Fadda Anna Maria, Matricardi Pietro

Polyphenolic extract from tarocco (citrus sinensis L. Osbeck) clone "Lempso" exerts anti-inflammatory and antioxidant effects via NF-kB and Nrf-2 activation in murine macrophages.

pubblicato su: NUTRIENTS - 2018

Pepe Giacomo, Sommella Eduardo, Cianciarulo Donato, Ostacolo Carmine, Manfra Michele, Di Sarno Veronica, Musella Simona, Russo Mariateresa, Messore Antonella, Parrino Barbara, Bertamino Alessia, Autore Giuseppina, Marzocco Stefania, Campiglia Pietro

Antioxidant properties of buffalo-milk dairy products: A β-Lg peptide released after gastrointestinal digestion of buffalo ricotta cheese reduces oxidative stress in intestinal epithelial cells

pubblicato su: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2018

Basilicata M. G., Pepe G., Adesso S., Ostacolo C., Sala M., Sommella E., Scala M. C., Messore A., Autore G., Marzocco S., Campiglia P.

Proof-of-concept of electrical activation of liposome nanocarriers: from dry to wet experiments

pubblicato su: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY - 2020

Caramazza Laura, Nardoni Martina, De Angelis Annalisa, Paolicelli Patrizia, Liberti Micaela, Apollonio Francesca, Petralito Stefania

Feasibility of drug delivery mediated by ultra-short and intense pulsed electric fields

pubblicato su: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - 2019

Caramazza Laura, Petralito Stefania, Nardoni Martina, De Angelis Annalisa, della Valle Elena, Denzi Agnese, Paolicelli Patrizia, Merla Caterina, Liberti Micaela, Apollonio Francesca

Numerical investigations of CW electric fields on lipid vesicles for controlled drug delivery

pubblicato su: 2019 49th European Microwave Conference, EuMC 2019 - 2019

Caramazza L., De Angelis A., Della Valle E., Denzi A., Nardoni M., Paolicelli P., Petralito S., Apollonio F., Liberti M.

Real-time CARS microspectroscopy to follow changes of membrane associated water molecules induced by the electropulsation of liposomes

pubblicato su: Proceeding of the 3rd World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine, and Food & Environmental Technologies - 2019

Merla C., Nardoni M., Scherman M., Petralito S., Apollonio F., Liberti M., Paolicelli P., Mir L. M., Attal-Tretout. B.

From vacuum to atmospheric pressure: A review of ambient ion soft landing

pubblicato su: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY - 2020

Tata A., Salvitti C., Pepi F.

A versatile magnetic exposure system for in-vitro, ex-vivo, and in-vivo experiments ifnalized to therapeutic applications in the IF range

pubblicato su: IEEE JOURNAL OF ELECTROMAGNETICS, RF AND MICROWAVES IN MEDICINE AND BIOLOGY. - 2019

Della Valle E., Liberti M., Camera F., Paffi A., Petralito S., Roncace V., Burattini C., Aicardi G., Apollonio F.

Phenyl(thio)phosphon(amid)ate benzenesulfonamides as potent and selective inhibitors of human carbonic anhydrases II and VII counteract allodynia in a mouse model of oxaliplatin-induced neuropathy

pubblicato su: JOURNAL OF MEDICINAL CHEMISTRY - 2020

Nocentini A., Alterio V., Bua S., Micheli L., Esposito D., Buonanno M., Bartolucci G., Osman S. M., ALOthman Z. A., Cirilli R., Pierini M., Monti S. M., Di Cesare Mannelli L., Gratteri P., Ghelardini C., De Simone G., Supuran C. T.

Chiral (cyclopentadienone)iron complexes with a stereogenic plane as pre-catalysts for the asymmetric hydrogenation of polar double bonds

pubblicato su: TETRAHEDRON - 2019

Bai Xishan, Cettolin Mattia, Mazzoccanti Giulia, Pierini Marco, Piarulli Umberto, Colombo Valentina, Dal Corso Alberto, Pignataro Luca, Gennari Cesare

TetraPh-Tol-BITIOPO: a new atropisomeric 3,3’-bithiophene based phosphine oxide as organocatalyst in Lewis Base-catalyzed Lewis Acid mediated reactions

pubblicato su: ORGANIC & BIOMOLECULAR CHEMISTRY - 2019

Mirco Abbinante Vincenzo, Benaglia Maurizio, Rossi Sergio, Benincori Tiziana, Cirilli Roberto, Pierini Marco

Ionic Liquids as "Masking" solvents of the relative strength of bases in proton transfer reactions

pubblicato su: CHEMPLUSCHEM - 2018

Zappacosta Romina, Di Crescenzo Antonello, Ettorre Valeria, Fontana Antonella, Pierini Marco, Siani Gabriella