Maria Elena Miranda Banos


Titolo Pubblicato in Anno
Glucocorticoids rescue cell surface trafficking of R451C Neuroligin3 and enhance synapse formation TRAFFIC 2024
Probing of the reactive center loop region of alpha-1-antitrypsin by mutagenesis predicts new type-2 dysfunctional variants CELLULAR AND MOLECULAR LIFE SCIENCES 2024
Thymol-functionalized hyaluronic acid as promising preservative biomaterial for the Inhibition of Candida albicans biofilm formation ACS MACRO LETTERS 2023
Targeting the Antifungal Activity of Carbon Dots against Candida albicans Biofilm Formation by Tailoring Their Surface Functional Groups CHEMISTRY-A EUROPEAN JOURNAL 2023
Novel Insights into the Link Between Myeloperoxidase Modified LDL, LOX-1, and Neuroserpin in Stroke REVIEWS IN CARDIOVASCULAR MEDICINE 2023
Polymerogenic neuroserpin causes mitochondrial alterations and activates NFκB but not the UPR in a neuronal model of neurodegeneration FENIB CELLULAR AND MOLECULAR LIFE SCIENCES 2022
Elucidating the pathological mechanisms of neurodegeneration in the lethal serpinopathy FENIB NEURAL REGENERATION RESEARCH 2022
Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD BRAIN PATHOLOGY 2021
The Importance of N186 in the Alpha-1-Antitrypsin Shutter Region Is Revealed by the Novel Bologna Deficiency Variant INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic SCIENTIFIC REPORTS 2021
Neuroserpin Inclusion Bodies in a FENIB Yeast Model MICROORGANISMS 2021
Neuroserpin: structure, function, physiology and pathology CELLULAR AND MOLECULAR LIFE SCIENCES 2021
Association between circulating alpha-1 antitrypsin polymers and lung and liver disease RESPIRATORY RESEARCH 2021
Glycosylation tunes neuroserpin physiological and pathological properties INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Embelin as lead compound for new neuroserpin polymerization inhibitors LIFE 2020
The alpha-1 antitrypsin polymer load correlates with hepatocyte senescence, fibrosis stage and liver-related mortality CHRONIC OBSTRUCTIVE PULMONARY DISEASES 2020
Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin JCI INSIGHT 2020
The structural basis for Z α1-antitrypsin polymerization in the liver SCIENCE ADVANCES 2020
The molecular species responsible for α1-antitrypsin deficiency are suppressed by a small molecule chaperone THE FEBS JOURNAL 2020
Yeast response to the expression of human proteins involved in proteinopathies 7th conference of Physiology of yeast and filamentous fungi 2019


  • LS1_4
  • LS3_6
  • LS5_11

Interessi di ricerca

Cell responses to protein aggregation; endoplasmic reticulum stress; neuronal toxicity of neuroserpin polymers that accumulate within the endoplasmic reticulum; mechanism of polymer formation in the serpinopathies; conformation-specific monoclonal antibodies against alpha-1 antitrypsin


Endoplasmic reticulum
Alpha 1 antitrypsin
Neuronal death
Familial encephalopathy with neuroserpin inclusion bodies

Laboratori di ricerca

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