Giampiero Ferraguti

Pubblicazioni

Titolo Pubblicato in Anno
Serum Lipocalin-2 Levels as a Biomarker in Pre- and Post-Pubertal Klinefelter Syndrome Patients: A Pilot Study INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2024
The RNA-binding protein SMN as a novel player in laryngeal squamous cell carcinoma INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
SMN deficiency destabilizes ABCA1 expression in human fibroblasts: novel insights in pathophysiology of spinal muscular atrophy INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
COVID-19 affects serum brain-derived neurotrophic factor and neurofilament light chain in aged men. Implications for morbidity and mortality CELLS 2023
Urine Dipstick Analysis on Automated Platforms: Is a Reliable Screening Tool for Proteinuria? An Experience from Umberto I Hospital in Rome BIOMEDICINES 2023
Autoimmune Polyendocrine Syndromes in the Pediatric Age CHILDREN 2023
Blood Biomarkers from the Emergency Department Disclose Severe Omicron COVID-19-Associated Outcomes MICROORGANISMS 2023
The Impact of ROS and NGF in the Gliomagenesis and their Emerging Implications in the Glioma Treatment CNS & NEUROLOGICAL DISORDERS. DRUG TARGETS 2023
Neuroimmune dysregulation in prepubertal and adolescent individuals affected by Klinefelter syndrome ENDOCRINE, METABOLIC & IMMUNE DISORDERS. DRUG TARGETS 2023
The Impact of Alcohol Consumption and Oral Microbiota on Upper Aerodigestive Tract Carcinomas: A Pilot Study ANTIOXIDANTS 2023
Oxidative stress in a mother consuming alcohol during pregnancy and in her newborn. a case report ANTIOXIDANTS 2023
Perinatal S-Adenosylmethionine Supplementation Represses PSEN1 Expression by the Cellular Epigenetic Memory of CpG and Non-CpG Methylation in Adult TgCRD8 Mice INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Quantitative evaluation of CFTR gene expression: a comparison between relative quantification by real-time PCR and absolute quantification by droplet digital PCR GENES 2023
Investigating biomarkers for COVID-19 morbidity and mortality CURRENT TOPICS IN MEDICINAL CHEMISTRY 2023
The Impact of Alcohol-Induced Epigenetic Modifications in the Treatment of Alcohol Use Disorders CURRENT MEDICINAL CHEMISTRY 2023
Nerve growth factor and autoimmune diseases CURRENT ISSUES IN MOLECULAR BIOLOGY 2023
Early routine biomarkers of SARS-CoV-2 morbidity and mortality: outcomes from an emergency section DIAGNOSTICS 2022
Safety of multiple vaccinations and durability of vaccine‐induced antibodies in an Italian military cohort 5 years after immunization BIOMEDICINES 2022
Alcohol and head and neck cancer: updates on the role of oxidative stress, genetic, epigenetics, oral microbiota, antioxidants, and alkylating agents ANTIOXIDANTS 2022
Exploring mitochondrial localization of SARS-CoV-2 RNA by padlock assay: a pilot study in human placenta INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022

ERC

  • LS2_1
  • LS5

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Studia la dipendenza da alcool, con particolare riguardo all’aspetto molecolare e alle sue basi genetiche, il rischio e l’effetto dell’esposizione fetale all’alcool (sindrome feto-alcolica). Ricerca nuovi marcatori di abuso alcolico e analizza geni relativi alla neurotrasmissione coinvolti nel fenomeno della dipendenza, con particolare attenzione ai recettori oppioidi e al trasportatore della serotonina (5-HTT). Le sue ricerche si focalizzano sulla regolazione trascrizionale in relazione alla presenza di modificazioni epigenetiche e di polimorfismi a singolo nucleotide (SNP).

Object of its studies is alcohol dependence, with particular regard to the molecular aspect and its genetic basis, the risk and effect of fetal exposure to alcohol (fetal alcoholic syndrome). He searches for new markers of alcohol abuse and analyzes genes related to neurotransmission involved in the phenomenon of addiction, with particular attention to opioid receptors and the serotonin transporter (5-HTT). His research focuses on transcriptional regulation in relation to the presence of epigenetic modifications and single nucleotide polymorphisms (SNPs).

Keywords

addiction
biochemistry genetics and molecular biology
alcohol
FASD

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