Lucia Nencioni

Pubblicazioni

Titolo Pubblicato in Anno
Recurrent Herpes simplex virus type 1 (HSV-1) infection modulates neuronal aging marks in in vitro and In vivo models INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Aminomalononitrile inspired prebiotic chemistry as a novel multicomponent tool for the synthesis of imidazole and purine derivatives with anti-influenza A virus activity. RSC ADVANCES 2021
System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2021
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2021
Rapid inactivation of SARS-CoV-2 with LED irradiation of visible spectrum wavelengths JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY. B, BIOLOGY 2021
Protective Role of Combined Polyphenols and Micronutrients against Influenza A Virus and SARS-CoV-2 Infection in vitro. BIOMEDICINES 2021
Redox-Modulating Agents in the Treatment of Viral Infections INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Counteraction of HCV-induced oxidative stress concurs to establish chronic infection in liver cell cultures OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2019
Glutathione increase by the n-butanoyl glutathione derivative (GSH-C4) inhibits viral replication and induces a predominant Th1 immune profile in old mice infected with influenza virus FASEB BIOADVANCES 2019
Role of glutathionylation in infection and inflammation NUTRIENTS 2019
Synthesis of stilbene and chalcone inhibitors of influenza A virus by SBA-15 Supported Hoveyda-Grubbs metathesis CATALYSTS 2019
The amphibian antimicrobial peptide temporin B inhibits in vitro herpes simplex virus type 1 infection ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2018
Antiviral and antioxidant activity of a hydroalcoholic extract from Humulus lupulus L. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2018
A polyphenol rich extract from Solanum melongena L. DR2 peel exhibits antioxidant properties and anti-herpes simplex virus type 1 activity in vitro MOLECULES 2018
Differential redox state contributes to sex disparities in the response to influenza virus infection in male and female mice FRONTIERS IN IMMUNOLOGY 2018
Redox alteration in patients infected by different HCV genotypes LE INFEZIONI IN MEDICINA 2018
Regioselective IBX-Mediated Synthesis of Coumarin Derivatives with Anti-oxidant and Anti-influenza Activities JOURNAL OF NATURAL PRODUCTS 2017
Antiviral and antioxidant activity of a hydroalcoholic extract from Humulus lupulus L. Atti del Convegno 2017
Validation of a reversed-phase high performance liquid chromatography method for the simultaneous analysis of cysteine and reduced glutathione in mouse organs OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2016
MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: Role of Hsp90 acetylation FUTURE MEDICINAL CHEMISTRY 2016

ERC

  • LS1
  • LS6_5
  • LS6_6
  • LS6_7
  • LS6_8

Interessi di ricerca

  • Study of the molecular mechanisms involved in regulation of respiratory virus replication and host cell response (death/survival; inflammatory and immune response);
  • Study of relationship between intra/extracellular redox state and viral infection and evaluation of antiviral effect of compounds with antioxidant activity in vitro and in vivo models.
  • Study of new antiviral strategies aimed at inhibiting host cell functions, rather than viral structure, that are essential for replication of different viruses. Identification and characterization of new synthesized or natural antiviral compounds.
  • Evaluation of antiviral activity of new synthesized or natural molecules in vitro and in vivo models.
  • Study of cooperation between different pathogens (bacteria and viruses) in the pathogenesis of acute and chronic diseases.

Keywords

redox state
influenza virus
Coronavirus
Glutathione
respiratory virus
antiviral activity
inflammation

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