Lucia Nencioni


Titolo Pubblicato in Anno
Influenza virus replication is affected by glutaredoxin1-mediated protein deglutathionylation THE FASEB JOURNAL 2023
Targeting SARS-CoV-2 by synthetic dual-acting thiol compounds that inhibit Spike/ACE2 interaction and viral protein production THE FASEB JOURNAL 2023
NRF2 Antioxidant Response and Interferon-Stimulated Genes Are Differentially Expressed in Respiratory-Syncytial-Virus- and Rhinovirus-Infected Hospitalized Children PATHOGENS 2023
Identification of anti-influenza A compounds inhibiting the NS-1 viral protein using a type I IFN-driven screening strategy INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Antimicrobial peptides for novel antiviral strategies in the current post-COVID-19 pandemic JOURNAL OF PEPTIDE SCIENCE 2023
Dysregulation of intracellular redox homeostasis by the SARS-CoV-2 ORF6 protein VIROLOGY JOURNAL 2023
ECHOPvir: A Mixture of Echinacea and Hop Extracts Endowed with Cytoprotective, Immunomodulatory and Antiviral Properties NUTRIENTS 2023
Influenza virus down-modulates G6PD expression and activity to induce oxidative stress and promote its replication FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY 2022
Broad-spectrum antiviral activity of the amphibian antimicrobial peptide temporin L and its analogs INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Ultrastructural damages to H1N1 influenza virus caused by vapor essential oils MOLECULES 2022
Antifungal activity of the frog skin peptide Temporin G and its effect on Candida albicans virulence factors INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
The inhibition of DNA viruses by the amphibian antimicrobial peptide temporin G. A virological study addressing HSV-1 and JPCyV INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Gut microbiota structure and metabolites, before and ater treatment in early rheumatoid arthritis patients. A pilot study FRONTIERS IN MEDICINE 2022
Multicomponent synthesis of diaminopurine and guanine PNA’s analogues active against influenza A virus from prebiotic compounds. ACS OMEGA 2022
Nitrostilbenes. Synthesis and biological evaluation as potential anti-influenza virus agents PHARMACEUTICALS 2022
Valorisation of an Italian mountain variety of Echinacea purpurea (L.) Moench: a sustainable strategy for medicinal plant production 41° Congresso Nazionale della Società Italiana di Farmacologia - Il valore scientifico e l'uso appropriato del farmaco 2022
Temporin G, an amphibian antimicrobial peptide against influenza and parainfluenza respiratory viruses: insights into biological activity and mechanism of action THE FASEB JOURNAL 2021
Laccase-Catalyzed 1,4-Dioxane-Mediated Synthesis of Belladine N-Oxides with Anti-Influenza A Virus Activity INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Intracellular redox-modulated pathways as targets for effective approaches in the treatment of viral infection INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021
Investigation of Commiphora myrrha (Nees) Engl. Oil and Its Main Components for Antiviral Activity PHARMACEUTICALS 2021


  • LS1
  • LS6_5
  • LS6_6
  • LS6_7
  • LS6_8

Interessi di ricerca

  • Study of the molecular mechanisms involved in regulation of respiratory virus replication and host cell response (death/survival; inflammatory and immune response);
  • Study of relationship between intra/extracellular redox state and viral infection and evaluation of antiviral effect of compounds with antioxidant activity in vitro and in vivo models.
  • Study of new antiviral strategies aimed at inhibiting host cell functions, rather than viral structure, that are essential for replication of different viruses. Identification and characterization of new synthesized or natural antiviral compounds.
  • Evaluation of antiviral activity of new synthesized or natural molecules in vitro and in vivo models.
  • Study of cooperation between different pathogens (bacteria and viruses) in the pathogenesis of acute and chronic diseases.


redox state
influenza virus
respiratory virus
antiviral activity

Laboratori di ricerca

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