Lucia Nencioni

Pubblicazioni

Titolo Pubblicato in Anno
Antiviral and antioxidant activity of a hydroalcoholic extract from Humulus lupulus L. Atti del convegno 2017
Validation of a reversed-phase high performance liquid chromatography method for the simultaneous analysis of cysteine and reduced glutathione in mouse organs OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2016
MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: Role of Hsp90 acetylation FUTURE MEDICINAL CHEMISTRY 2016
Influenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS CELLULAR MICROBIOLOGY 2015
New 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides inhibit hepatitis C virus replication via suppression of cyclooxygenase-2 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2015
Influenza A virus infection of intestinal epithelial cells enhances the adhesion ability of Crohn's disease associated Escherichia coli strains PLOS ONE 2015
Redox proteomics of the inflammatory secretome identifies a common set of redoxins and other glutathionylated proteins released in inflammation, influenza virus infection and oxidative stress PLOS ONE 2015
LOW GLUCOSE IN THE HOST CELL IMPAIRS INFLUENZA VIRUS REPLICATION 2015
Temporin B, an amphibian antimicrobial peptide, is able to inhibit in vitro Herpes Simplex type 1 2015
Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses. BIOORGANIC & MEDICINAL CHEMISTRY 2015

ERC

  • LS1
  • LS6_5
  • LS6_6
  • LS6_7
  • LS6_8

Interessi di ricerca

  • Study of the molecular mechanisms involved in regulation of respiratory virus replication and host cell response (death/survival; inflammatory and immune response);
  • Study of relationship between intra/extracellular redox state and viral infection and evaluation of antiviral effect of compounds with antioxidant activity in vitro and in vivo models.
  • Study of new antiviral strategies aimed at inhibiting host cell functions, rather than viral structure, that are essential for replication of different viruses. Identification and characterization of new synthesized or natural antiviral compounds.
  • Evaluation of antiviral activity of new synthesized or natural molecules in vitro and in vivo models.
  • Study of cooperation between different pathogens (bacteria and viruses) in the pathogenesis of acute and chronic diseases.

Keywords

redox state
influenza virus
Coronavirus
Glutathione
respiratory virus
antiviral activity
inflammation

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma