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f.fiorentino@uniroma1.it
Francesco Fiorentino
Assegnista di ricerca
Struttura:
DIPARTIMENTO DI CHIMICA E TECNOLOGIE DEL FARMACO
E-mail:
f.fiorentino@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2023
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence
JOURNAL OF MEDICINAL CHEMISTRY
2023
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey
JOURNAL OF MEDICINAL CHEMISTRY
2023
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2023
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection
CELLS
2023
Native mass spectrometry-directed drug discovery: Recent advances in investigating protein function and modulation
DRUG DISCOVERY TODAY
2023
Rationalizing the Optimization of Detergents for Membrane Protein Purification
CHEMISTRY
2023
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription
NUCLEIC ACIDS RESEARCH
2022
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2022
Sirtuin modulators: past, present, and future perspectives
FUTURE MEDICINAL CHEMISTRY
2022
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5
JOURNAL OF MEDICINAL CHEMISTRY
2022
Mass Spectrometry Analysis of Dynamics and Interactions of the LPS Translocon LptDE
Lipopolysaccharide Transport
2022
Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1
MICROORGANISMS
2022
The two-faced role of sirt6 in cancer
CANCERS
2021
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
2021
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions
CHEMICAL COMMUNICATIONS
2021
NaViA: A Program for the Visual Analysis of Complex Mass Spectra
BIOINFORMATICS
2021
Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide
NATURE CHEMICAL BIOLOGY
2021
Anionic Dendritic Polyglycerol for Protein Purification and Delipidation
ACS APPLIED POLYMER MATERIALS
2021
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Keywords
medicinal chemistry
biophysical chemistry
epigenetics
antimicrobial resistance
high resolution mass spectrometry
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