Francesco Fiorentino | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2023
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence	JOURNAL OF MEDICINAL CHEMISTRY	2023
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey	JOURNAL OF MEDICINAL CHEMISTRY	2023
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII	JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY	2023
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection	CELLS	2023
Native mass spectrometry-directed drug discovery: Recent advances in investigating protein function and modulation	DRUG DISCOVERY TODAY	2023
Rationalizing the Optimization of Detergents for Membrane Protein Purification	CHEMISTRY	2023
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription	NUCLEIC ACIDS RESEARCH	2022
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2022
Sirtuin modulators: past, present, and future perspectives	FUTURE MEDICINAL CHEMISTRY	2022
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5	JOURNAL OF MEDICINAL CHEMISTRY	2022
Mass Spectrometry Analysis of Dynamics and Interactions of the LPS Translocon LptDE	Lipopolysaccharide Transport	2022
Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1	MICROORGANISMS	2022
The two-faced role of sirt6 in cancer	CANCERS	2021
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives	JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY	2021
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions	CHEMICAL COMMUNICATIONS	2021
NaViA: A Program for the Visual Analysis of Complex Mass Spectra	BIOINFORMATICS	2021
Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide	NATURE CHEMICAL BIOLOGY	2021
Anionic Dendritic Polyglycerol for Protein Purification and Delipidation	ACS APPLIED POLYMER MATERIALS	2021

Keywords

medicinal chemistry

biophysical chemistry

epigenetics

antimicrobial resistance

high resolution mass spectrometry