Francesco Fiorentino

Pubblicazioni

Titolo Pubblicato in Anno
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity JOURNAL OF MEDICINAL CHEMISTRY 2024
Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2023
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence JOURNAL OF MEDICINAL CHEMISTRY 2023
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey JOURNAL OF MEDICINAL CHEMISTRY 2023
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2023
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection CELLS 2023
Native mass spectrometry-directed drug discovery: Recent advances in investigating protein function and modulation DRUG DISCOVERY TODAY 2023
Rationalizing the Optimization of Detergents for Membrane Protein Purification CHEMISTRY 2023
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8 JOURNAL OF MEDICINAL CHEMISTRY 2023
Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa. MICROBIOLOGICAL RESEARCH 2023
The role of structural biology in the design of sirtuin activators CURRENT OPINION IN STRUCTURAL BIOLOGY 2023
State of the art of carbonic anhydrase activators FUTURE MEDICINAL CHEMISTRY 2023
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription NUCLEIC ACIDS RESEARCH 2022
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2022
Sirtuin modulators: past, present, and future perspectives FUTURE MEDICINAL CHEMISTRY 2022
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5 JOURNAL OF MEDICINAL CHEMISTRY 2022
Mass Spectrometry Analysis of Dynamics and Interactions of the LPS Translocon LptDE Lipopolysaccharide Transport 2022
Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1 MICROORGANISMS 2022
The two-faced role of sirt6 in cancer CANCERS 2021

Keywords

medicinal chemistry
biophysical chemistry
epigenetics
antimicrobial resistance
high resolution mass spectrometry

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