| Titolo |
Pubblicato in |
Anno |
| Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity |
JOURNAL OF MEDICINAL CHEMISTRY |
2024 |
| Detergents with Scalable Properties Identify Noncanonical Lipopolysaccharide Binding to Bacterial Inner Membrane Proteins |
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
2024 |
| Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells |
CHEMMEDCHEM |
2024 |
| A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection |
PLOS BIOLOGY |
2024 |
| (Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling |
ACS INFECTIOUS DISEASES |
2024 |
| m6A modification inhibits miRNAs’ intracellular function, favoring their extracellular export for intercellular communication |
CELL REPORTS |
2024 |
| STRUCTURE-BASED MECHANISM OF RIBOREGULATION OF THE METABOLIC ENZYME SHMT1 |
MOLECULAR CELL |
2024 |
| Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development |
PHARMACEUTICALS |
2024 |
| Activation and inhibition of sirtuins: From bench to bedside |
MEDICINAL RESEARCH REVIEWS |
2024 |
| GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis |
BRAIN, BEHAVIOR, AND IMMUNITY |
2024 |
| Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity |
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY |
2023 |
| Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence |
JOURNAL OF MEDICINAL CHEMISTRY |
2023 |
| METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey |
JOURNAL OF MEDICINAL CHEMISTRY |
2023 |
| Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII |
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY |
2023 |
| Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection |
CELLS |
2023 |
| Native mass spectrometry-directed drug discovery: Recent advances in investigating protein function and modulation |
DRUG DISCOVERY TODAY |
2023 |
| Rationalizing the Optimization of Detergents for Membrane Protein Purification |
CHEMISTRY |
2023 |
| First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8 |
JOURNAL OF MEDICINAL CHEMISTRY |
2023 |
| Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa. |
MICROBIOLOGICAL RESEARCH |
2023 |
| The role of structural biology in the design of sirtuin activators |
CURRENT OPINION IN STRUCTURAL BIOLOGY |
2023 |
