Giovanna Simonetti

Pubblicazioni

Titolo Pubblicato in Anno
Valorization of Kiwi Peels. Fractionation, bioactives analyses and hypotheses on complete peels recycle FOODS 2022
Epigenetic cell memory Rethinking Orality I 2022
A novel approach to control Botrytis cinerea fungal infections: uptake and biological activity of antifungals encapsulated in nanoparticle based vectors SCIENTIFIC REPORTS 2022
Poly-(lactic-co-glycolic) acid nanoparticles entrapping pterostilbene for targeting aspergillus section nigri MOLECULES 2022
Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1 MICROORGANISMS 2022
Azole-based compounds that are active against Candida biofilm. In vitro, in vivo and In Silico studies ANTIBIOTICS 2022
Design, synthesis and biological evaluation of a series of iron and copper chelating deferiprone derivatives as new agents active against Candida albicans BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2021
Health potential of clery strawberries. Enzymatic Inhibition and anti-Candida activity evaluation MOLECULES 2021
Microfluidic synthesis of PLGA nanocarriers for the controlled delivery of bioactive compounds in plants of agronomic interest Applied Nanotechnology and Nanoscience International Conference 2021 2021
JQ1, inibitore delle proteine BET, riduce i fattori di virulenza e la patogenicità di Aspergillus fumigatus. 13° Congresso Nazionale della Società Italiana di Microbiologia Farmaceutica Obiettivi e Sfide della Microbiologia Moderna per la Difesa della Salute 2021
Microbiologia Farmaceutica 3. edizione 2021
Circular economy. Valorization of waste plant biomass to produce active ingredients with antimicrobial activity against human and plant pathogens An introduction to the circular economy 2021
Antifungal activity of Mongolian medicinal plant extracts NATURAL PRODUCT RESEARCH 2020
Phytochemical and biological characterization of Italian “sedano bianco di Sperlonga” protected geographical indication celery ecotype. A multimethodological approach FOOD CHEMISTRY 2020
In vitro antimicrobial activity of plant extracts against Pseudomonas syringae pv. actinidiae causal agent of bacterial canker in kiwifruit PLANT BIOSYSTEMS 2020
Anti-Candida albicans biofilm activity of extracts from two selected indigenous Algerian plants. Clematis flammula and Fraxinus angustifolia JOURNAL OF HERBAL MEDICINE 2020
Chemico-biological characterization of Torpedino Di Fondi® tomato fruits. A comparison with San Marzano cultivar at two ripeness stages ANTIOXIDANTS 2020
Antifungal activity of phenolic and polyphenolic compounds from different matrices of Vitis vinifera L. against human pathogens MOLECULES 2020
Phenolic content and in vitro antifungal activity of unripe grape extracts from agro-industrial wastes NATURAL PRODUCT RESEARCH 2019
Searching for new agents active against candida albicans biofilm: a series of indole derivatives, design, synthesis and biological evaluation EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2019

ERC

  • LS2_3
  • LS4_6
  • LS6_5
  • LS6_6
  • LS6_7
  • LS6_8
  • LS6_9

KET

  • Life-science technologies & biotechnologies
  • Sustainable technologies & development

Interessi di ricerca

La ricerca, incentrata su funghi patogeni e commensali dell'uomo, quali in particolare Candida spp, Aspergillus spp, Malassezia spp e dermatofiti,  riguarda:

lo studio dei meccanismi coinvolti nella virulenza, formazione di biofilm e nella acquisizione di resistenza ai farmaci antifungini;

lo studio dell’attività antimicrobica di nuove molecole naturali e di sintesi.

lo studio di modulatori epigenetici sull’inibizione della crescita e sui fattori di virulenza .

lo studio delle proteine extracellulari.

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Keywords

antimicrobial activity
antifungal activity assay
antifungal activity
virulence factors
Yeast
Aspergillus spp
Candida species
malassezia
dermatophytes

Progetti di Ricerca

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