Mariano Bizzarri


Titolo Pubblicato in Anno
When one size does not fit all: Reconsidering PCOS etiology, diagnosis, clinical subgroups, and subgroup-specific treatments ENDOCRINE AND METABOLIC SCIENCE 2024
Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery CELLS 2023
The Role of Inositols in the Hyperandrogenic Phenotypes of PCOS: A Re-Reading of Larner’s Results INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Myo-Inositol Reverses TGF-β1-Induced EMT in MCF-10A Non-Tumorigenic Breast Cells CANCERS 2023
Effects of Simulated Microgravity In Vitro on Human Metaphase II Oocytes: An Electron Microscopy-Based Study CELLS 2023
Is Cancer Reversible? Rethinking Carcinogenesis Models-A New Epistemological Tool BIOMOLECULES 2023
Impact of Oocyte Extract Supplement on Quality of Life after Hepatectomy for Liver Tumours: A Prospective, Multicentre, Double-Blind Randomized Clinical Trial CANCERS 2023
Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review NUTRIENTS 2023
A Critical Perspective on the Supplementation of Akkermansia muciniphila: Benefits and Harms LIFE 2023
ERK Signaling Pathway Is Constitutively Active in NT2D1 Non-Seminoma Cells and Its Inhibition Impairs Basal and HGF-Activated Cell Proliferation BIOMEDICINES 2023
Synchronization between Attractors: Genomic Mechanism of Cell-Fate Change INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Stereoselective Voltammetric Biosensor for Myo-Inositol and D-Chiro-Inositol Recognition SENSORS 2023
Systems biology and inborn error of metabolism: analytical strategy in investigating different biochemical/ genetic parameters Systems biology 2023
System Biology Approach in Investigating Epithelial-Mesenchymal Transition (EMT) Systems Biology, second edition 2023
Microgravity modifies the phenotype of fibroblast and promotes remodeling of the fibroblast–keratinocyte interaction in a 3D co-culture model INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Does Alpha-lipoic acid improve effects on polycystic ovary syndrome? EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES 2022
Microenvironment promotes cytoskeleton remodeling and adaptive phenotypic transition BIOCELL 2022
Space Biomedicine: A Unique Opportunity to Rethink the Relationships between Physics and Biology BIOMEDICINES 2022
Positive Effects of α-Lactalbumin in the Management of Symptoms of Polycystic Ovary Syndrome NUTRIENTS 2022
Allethrin Promotes Apoptosis and Autophagy Associated with the Oxidative Stress-Related PI3K/AKT/mTOR Signaling Pathway in Developing Rat Ovaries INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022


  • LS1_7
  • LS2
  • LS2_13
  • LS3_4
  • LS3_8


  • Life-science technologies & biotechnologies

Interessi di ricerca

Main research fields can be summarized as follows:

  • Systems Biology approach in the integrative understanding of cell and tumor biology, namely by focusing on cell phenotypic transition, tumor reversion and cell-microenvironment crosstalk
  • Biophysical constraints in carcinogenesis and cell fate commitment
  • Inositol in physiology and pathology
  • Metabolism and pharmacodynamics of network pharmacology
  • Cytoskeleton and fractal shape analysis

Space Biomedicine


simulated microgravity
cell fate transition

Laboratori di ricerca

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma