Isotta Chimenti


Titolo Pubblicato in Anno
Open challenges and new perspectives in cardiac regenerative medicine CURRENT STEM CELL RESEARCH & THERAPY 2020
The microenvironment of decellularized extracellular matrix from heart failure myocardium alters the balance between angiogenic and fibrotic signals from stromal primitive cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Inhibition of miR-155 Attenuates Detrimental Vascular Effects of Tobacco Cigarette Smoking JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE 2020
Innovative In Vitro Models for the Study of Lung Diseases Cell Interaction - Regulation of Immune Responses, Disease Development and Management Strategies 2020
Oral plaque from Type 2 diabetic patients reduces the clonogenic capacity of dental pulp-derived mesenchymal stem cells STEM CELLS INTERNATIONAL 2019
Automated segmentation of fluorescence microscopy images for 3D cell detection in human-derived cardiospheres SCIENTIFIC REPORTS 2019
Acute Effects of Heat-Not-Burn, Electronic Vaping, and Traditional Tobacco Combustion Cigarettes: The Sapienza University of Rome-Vascular Assessment of Proatherosclerotic Effects of Smoking ( SUR - VAPES ) 2 Randomized Trial JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE 2019
Pharmacological restoration of autophagy reduces hypertension-related stroke occurrence AUTOPHAGY 2019
On the road to regeneration. “Tools” and “Routes” towards efficient cardiac cell therapy for ischemic cardiomyopathy CURRENT CARDIOLOGY REPORTS 2019
Cardiac progenitor cells. The matrix has you STEM CELLS TRANSLATIONAL MEDICINE 2018
β-adrenergic receptors and cardiac progenitor cell biology. What is the real connection? JOURNAL OF CELLULAR BIOCHEMISTRY 2018
Cell-derived exosomes for cardiovascular therapies: Y (not) RNAs? HYPERTENSION 2018
The biological mechanisms of action of cardiac progenitor cell therapy CURRENT CARDIOLOGY REPORTS 2018
Beta2-adrenergic signaling affects the phenotype of human cardiac progenitor cells through EMT modulation PHARMACOLOGICAL RESEARCH 2018
Predictors of oxidative stress and vascular function in an experimental study of tobacco versus electronic cigarettes. A post hoc analysis of the SUR-VAPES 1 study TOBACCO INDUCED DISEASES 2018
Cardiac mechano-perception. A life-long story from early beats to aging and failure STEM CELLS AND DEVELOPMENT 2017
Human lung spheroids as In vitro niches of lung progenitor cells with distinctive paracrine and plasticity properties STEM CELLS TRANSLATIONAL MEDICINE 2017
Stem cell spheroids and ex vivo niche modeling. Rationalization and scaling-up JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH 2017
Cardiac recovery during long-term LVAD. is there an interaction between beta-blockers and cardiac progenitor cells JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 2017
Cytoprotective and antioxidant effects of steen solution on human lung spheroids and human endothelial cells AMERICAN JOURNAL OF TRANSPLANTATION 2017


  • LS3_2
  • LS3_12
  • LS4_1
  • LS4_10
  • LS7_4


  • Life-science technologies & biotechnologies

Interessi di ricerca

Cardiac stromal cells; repair and paracrine mechanisms; regenerative medicine; cardiac microenvironment; cardiac tissue engineering; cell therapy; oxidative and metabolic stress the cardiovascular system; mechano-sensing.


cardiac stromal cells
cardiac fibrosis
2D/3D models
cardiac tissue engineering/regenerative medicine
paracrine signals

Gruppi di ricerca

Gruppi di ricerca - Responsabile

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