Isotta Chimenti | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Early Impairment of Paracrine and Phenotypic Features in Resident Cardiac Mesenchymal Stromal Cells after Thoracic Radiotherapy	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2024
Recent advances in 3D cultures	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2024
Exposure to serum from exclusive heated tobacco product smokers induces mTOR activation and fibrotic features in human cardiac stromal cells	BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE	2024
3D Cultures for Modelling the Microenvironment: Current Research Trends and Applications	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2023
Editorial: The cardiac stroma in homeostasis and disease	FRONTIERS IN CARDIOVASCULAR MEDICINE	2023
A review of therapeutic strategies against cardiac fibrosis. From classical pharmacology to novel molecular, epigenetic, and biotechnological approaches	REVIEWS IN CARDIOVASCULAR MEDICINE	2023
Effect of traditional or heat-not-burn cigarette smoking on circulating miRNAs in healthy subjects	EUROPEAN JOURNAL OF CLINICAL INVESTIGATION	2023
The role of charme in the phenotype and function of resident cardiac mesenchymal stromal cells	EUROPEAN HEART JOURNAL	2023
Fibrosis and inflammation in tissue pathophysiology	FRONTIERS IN PHYSIOLOGY	2022
Cardiac stromal cells on stage. From dull filler to specialized actors	BIOCELL	2022
The dynamic facets of the cardiac stroma. Fom classical markers to omics and translational perspectives	AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH	2022
The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress	CELL DEATH DISCOVERY	2022
Aging-Related Decline of Autophagy in Patients with Atrial Fibrillation—A Post Hoc Analysis of the ATHERO-AF Study	ANTIOXIDANTS	2022
Progressive stages of dysmetabolism are associated with impaired biological features of human cardiac stromal cells mediated by the oxidative state and autophagy	JOURNAL OF PATHOLOGY	2022
Reduction of Cardiac Fibrosis by Interference With YAP-Dependent Transactivation	CIRCULATION RESEARCH	2022
Human platelet lysate‐derived extracellular vesicles enhance angiogenesis through miR‐126	CELL PROLIFERATION	2022
Modified risk tobacco products and cardiovascular repair: still very smoky	CURRENT STEM CELL RESEARCH & THERAPY	2022
Multicellular 3D models for the study of cardiac fibrosis	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
Fibrosis and inflammation in tissue pathophysiology		2022
Sex-Related Differences in Oxidative, Platelet, and Vascular Function in Chronic Users of Heat-not-Burn vs. Traditional Combustion Cigarettes	ANTIOXIDANTS	2022

ERC

LS3_2
LS3_12
LS4_1
LS4_10
LS7_4

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Cardiac stromal cells; repair and paracrine mechanisms; regenerative medicine; cardiac microenvironment; cardiac tissue engineering; cell therapy; oxidative and metabolic stress the cardiovascular system; mechano-sensing.

Keywords

cardiac stromal cells

cardiac fibrosis

2D/3D models

cardiac tissue engineering/regenerative medicine

paracrine signals

Progetti di Ricerca

Novel perspectives in cardio-oncology: Early MEchanisms of caRdiotoxicity and strateGiEs for adjuvaNt Therapy (EMERGENT)
Boosting cardiac regeneration through the interplay between cardiac stromal cells and the microenvironment.

Gruppi di ricerca

Autophagy and Cardiovascular Diseases

Gruppi di ricerca - Responsabile

Patologia e Riparazione Cardiovascolare

Laboratori di ricerca

Laboratorio di Patologia e Riparazione Cardiovascolare.