Isotta Chimenti


Titolo Pubblicato in Anno
3D Cultures for Modelling the Microenvironment: Current Research Trends and Applications INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Fibrosis and inflammation in tissue pathophysiology FRONTIERS IN PHYSIOLOGY 2022
Cardiac stromal cells on stage. From dull filler to specialized actors BIOCELL 2022
The dynamic facets of the cardiac stroma. Fom classical markers to omics and translational perspectives AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH 2022
The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress CELL DEATH DISCOVERY 2022
Aging-Related Decline of Autophagy in Patients with Atrial Fibrillation—A Post Hoc Analysis of the ATHERO-AF Study ANTIOXIDANTS 2022
Progressive stages of dysmetabolism are associated with impaired biological features of human cardiac stromal cells mediated by the oxidative state and autophagy JOURNAL OF PATHOLOGY 2022
Reduction of Cardiac Fibrosis by Interference With YAP-Dependent Transactivation CIRCULATION RESEARCH 2022
Human platelet lysate‐derived extracellular vesicles enhance angiogenesis through miR‐126 CELL PROLIFERATION 2022
Modified risk tobacco products and cardiovascular repair: still very smoky CURRENT STEM CELL RESEARCH & THERAPY 2022
Multicellular 3D models for the study of cardiac fibrosis INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Fibrosis and inflammation in tissue pathophysiology 2022
Sex-Related Differences in Oxidative, Platelet, and Vascular Function in Chronic Users of Heat-not-Burn vs. Traditional Combustion Cigarettes ANTIOXIDANTS 2022
Procedure cardiovascolari. Terapia cellulare cardiaca Malattie cardiovascolari. Approccio clinico e scientifico 2022
Impact of chronic use of heat-not-burn cigarettes on oxidative stress, endothelial dysfunction and platelet activation. The SUR-VAPES Chronic Study THORAX 2021
A snapshot global survey on side effects of COVID-19 vaccines among healthcare professionals and armed forces with a focus on headache PANMINERVA MEDICA 2021
Profiling the acute effects of modified risk products. Evidence from the SUR-VAPES (Sapienza University of Rome-Vascular Assessment of Proatherosclerotic Effects of Smoking) cluster study CURRENT ATHEROSCLEROSIS REPORTS 2020
Building an artificial cardiac microenvironment. A focus on the extracellular matrix FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2020
Open challenges and new perspectives in cardiac regenerative medicine CURRENT STEM CELL RESEARCH & THERAPY 2020
The microenvironment of decellularized extracellular matrix from heart failure myocardium alters the balance between angiogenic and fibrotic signals from stromal primitive cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020


  • LS3_2
  • LS3_12
  • LS4_1
  • LS4_10
  • LS7_4


  • Life-science technologies & biotechnologies

Interessi di ricerca

Primitive stromal cells; repair and paracrine mechanisms; regenerative medicine; cardiac microenvironment; cardiac tissue engineering; cell therapy; oxidative and metabolic stress the cardiovascular system; mechano-sensing.


2D/3D models
cardiac stromal cells
cardiac fibrosis
cardiac tissue engineering/regenerative medicine
paracrine signals

Gruppi di ricerca

Gruppi di ricerca - Responsabile

Laboratori di ricerca

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma