Isotta Chimenti | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
An overview of the inflammatory signalling mechanisms in the myocardium underlying the development of diabetic cardiomyopathy	CARDIOVASCULAR RESEARCH	2017
The Impact of Environmental Factors in Influencing Epigenetics Related to Oxidative States in the Cardiovascular System	OXIDATIVE MEDICINE AND CELLULAR LONGEVITY	2017
Histone acetylation favours the cardiovascular commitment of adipose tissue-derived stromal cells	INTERNATIONAL JOURNAL OF CARDIOLOGY	2017
A review of the molecular mechanisms underlying the development and progression of cardiac remodeling	OXIDATIVE MEDICINE AND CELLULAR LONGEVITY	2017
Normal versus pathological cardiac fibroblast-derived extracellular matrix differentially modulates cardiosphere-derived cell paracrine properties and commitment	STEM CELLS INTERNATIONAL	2017
EMT/MET at the crossroad of stemness, regeneration and oncogenesis. The Ying-Yang equilibrium recapitulated in cell spheroids	CANCERS	2017
Getting old through the blood. Circulating molecules in aging and senescence of cardiovascular regenerative cells	FRONTIERS IN CARDIOVASCULAR MEDICINE	2017
Sex differences of human cardiac progenitor cells in the biological response to TNF-α treatment	STEM CELLS INTERNATIONAL	2017
Exosomes isolation protocols. Facts and artifacts for cardiac regeneration	FRONTIERS IN BIOSCIENCE	2016
The adipose tissue of origin influences the biological potential of human adipose stromal cells isolated from mediastinal and subcutaneous fat depots	STEM CELL RESEARCH	2016
Β-blockers treatment of cardiac surgery patients enhances isolation and improves phenotype of cardiosphere-derived cells	SCIENTIFIC REPORTS	2016
Acute impact of tobacco vs electronic cigarette smoking on oxidative stress and vascular function	CHEST	2016
Role of NOX2 in mediating doxorubicin-induced senescence in human endothelial progenitor cells	MECHANISMS OF AGEING AND DEVELOPMENT	2016
Beta-blocker treatment impacts on resident cardiac progenitors isolation and therapeutic features in cardiac surgery patients.	ESC CONGRESS 2016	2016
Cardiosphere conditioned media influence the plasticity of human mediastinal adipose tissue-derived mesenchymal stem cells	CELL TRANSPLANTATION	2015
State of the art on the evidence base in cardiac regenerative therapy. Overview of 41 systematic reviews	BIOMED RESEARCH INTERNATIONAL	2015
An international survey on taking up a career in cardiovascular research. opportunities and biases toward would-be physician-scientists	PLOS ONE	2015
The potential of GMP-compliant platelet lysate to induce a permissive state for cardiovascular transdifferentiation in human mediastinal adipose tissue-derived mesenchymal stem cells	BIOMED RESEARCH INTERNATIONAL	2015
Bridging regenerative medicine based therapies into the 21st century. solo or symphony	INTERNATIONAL ARCHIVES OF MEDICINE	2015

ERC

LS3_2
LS3_12
LS4_1
LS4_10
LS7_4

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Cardiac stromal cells; repair and paracrine mechanisms; regenerative medicine; cardiac microenvironment; cardiac tissue engineering; cell therapy; oxidative and metabolic stress the cardiovascular system; mechano-sensing.

Keywords

cardiac stromal cells

cardiac fibrosis

2D/3D models

cardiac tissue engineering/regenerative medicine

paracrine signals

Progetti di Ricerca

Novel perspectives in cardio-oncology: Early MEchanisms of caRdiotoxicity and strateGiEs for adjuvaNt Therapy (EMERGENT)
Boosting cardiac regeneration through the interplay between cardiac stromal cells and the microenvironment.

Gruppi di ricerca

Autophagy and Cardiovascular Diseases

Gruppi di ricerca - Responsabile

Patologia e Riparazione Cardiovascolare