Paola Infante


Titolo Pubblicato in Anno
Potential of a natural compound as Hedgehog pathway inhibitor for the treatment of Intrahepatic Cholangiocarcinoma 30° CONGRESSO NAZIONALE DELLE MALATTIE DIGESTIVE 2024
Exploring the potential of anthraquinone-based hybrids for  identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour CHEMISTRY 2023
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma CELL DEATH AND DIFFERENTIATION 2023
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors? FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2022
Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 2022
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma CANCER LETTERS 2021
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors ONCOGENE 2021
Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors CHEMISTRY-A EUROPEAN JOURNAL 2021
Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis FRONTIERS IN MOLECULAR NEUROSCIENCE 2021
SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples ELIFE 2021
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma FRONTIERS IN CHEMISTRY 2021
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module CELL REPORTS 2020
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i CANCERS 2020
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present) EXPERT OPINION ON THERAPEUTIC PATENTS 2020
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer FRONTIERS IN ONCOLOGY 2020
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation CELL DEATH & DISEASE 2020
Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors CANCER IMMUNOLOGY RESEARCH 2020
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma EXPERT OPINION ON THERAPEUTIC TARGETS 2020
Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer CANCERS 2020
A simplified genomic profiling approach predicts outcome in metastatic colorectal cancer CANCERS 2019

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