Paola Infante | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Potential of a natural compound as Hedgehog pathway inhibitor for the treatment of Intrahepatic Cholangiocarcinoma	30° CONGRESSO NAZIONALE DELLE MALATTIE DIGESTIVE	2024
Dissecting the hindrance of Hedgehog pathway in Intrahepatic Cholangiocarcinoma: a step towards targeted therapy	UNITED EUROPEAN GASTROENTEROLOGY JOURNALUNITED EUROPEAN GASTROENTEROLOGY JOURNAL	2024
Exploring the potential of anthraquinone-based hybrids for identifying a novel generation of antagonists for the Smoothened receptor in HH-dependent tumour	CHEMISTRY	2023
SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma	CELL DEATH AND DIFFERENTIATION	2023
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors?	FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY	2022
Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH	2022
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma	CANCER LETTERS	2021
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors	ONCOGENE	2021
Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors	CHEMISTRY-A EUROPEAN JOURNAL	2021
Harnessing the activation of RIG-I like receptors to inhibit glioblastoma tumorigenesis	FRONTIERS IN MOLECULAR NEUROSCIENCE	2021
SMA-miRs (MiR-181a- 5p, -324-5p, and -451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples	ELIFE	2021
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma	FRONTIERS IN CHEMISTRY	2021
Phenformin inhibits hedgehog-dependent tumor growth through a complex i-independent redox/corepressor module	CELL REPORTS	2020
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i	CANCERS	2020
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present)	EXPERT OPINION ON THERAPEUTIC PATENTS	2020
Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer	FRONTIERS IN ONCOLOGY	2020
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation	CELL DEATH & DISEASE	2020
Nutlin-3a enhances natural killer cell-mediated killing of neuroblastoma by restoring p53-dependent expression of ligands for NKG2D and DNAM-1 receptors	CANCER IMMUNOLOGY RESEARCH	2020
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma	EXPERT OPINION ON THERAPEUTIC TARGETS	2020
Dubs activating the hedgehog signaling pathway: a promising therapeutic target in cancer	CANCERS	2020